N/A N=30 Headgear Accessory for Exercise-Induced Laryngeal Obstruction Studies
Exercise-Induced Laryngeal Obstruction
Primary: Percentage of Participants With Continuous Laryngoscopy During Exercise Tests — 100 percentage of participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=15 Inspiratory Muscle Training on The Severity of Exercise-Induced Bronchoconstriction and Time-Trial Performance (IMT_EIB)
Exercise Induced Bronchospasm · Exercise Induced Asthma
Primary: Exercise-Induced Bronchoconstriction (EIB) Severity — 19.84; 10.94 Percentage (%) — p=0.339
Phase 3 N=51 Montelukast in Exercise-Induced Bronchospasm - 2003 (0476-270)
Asthma, Exercise-Induced
Primary: Maximum Percent Fall in FEV1 After Exercise Challenge at 2 Hours Postdose Compared With Pre-exercise Baseline in Patients With Exercise-induced Bronchospasm (EIB)…
Phase 3 N=62 Montelukast in Exercise-Induced Bronchospasm - 2004 (0476-275)
Asthma, Exercise-Induced
Primary: Maximum Percent Fall in FEV1 After Exercise Challenge at 2 Hours Post-dose Compared With Pre-exercise Baseline in Patients With Exercise-induced Bronchospasm (EIB)…
Phase 3 N=47 Montelukast Compared With Placebo and Salmeterol in Exercise-Induced Bronchoconstriction (0476-316)
Asthma, Exercise-Induced
Primary: Maximum Percent Fall in Forced Expiratory Volume in 1 Second (FEV1) After Exercise Challenge at 2 Hours Post-dose in Patients With Exercise-Induced Bronchoconstriction…
N/A N=100 No Post Intubation Laryngeal Symptoms
Sore-throat · Dysphonia · Dysphagia
Primary: Sore Throat on a Scale From 0 (no Sore Throat) to 10 (Worst Possible Sore Throat) — 1.85; 1.9; 1.1; 1.62 score on a scale — p=0.03
Phase 4 N=20 Effectiveness of Ipratropium Bromide in Preventing Exercise-induced Bronchoconstriction in Athletes
Bronchospasm, Exercise-Induced
Primary: Spirometry and Specific Airway Conductance Measured by Body Plethysmography Before and After Exercise Challenge After Randomized Administration of Either Inhaled…
N/A N=133 Mechanisms of Upper Airway Obstruction
Obstructive Sleep Apnea
Primary: Pharyngeal Critical Pressure (Pcrit) — 1.26; -1.42; -1.06 cm H2O — p=.80
Phase 2 N=30 A Pilot Study of the Treatment of Eosinophilic Esophagitis With Omalizumab
Esophagitis
Primary: Change in Eosinophil Numbers Per High Power Field Proximally and Distally Between Baseline and Post-treatment and Between Both Groups — 0.6; -7.5 perecentage of eos per…
N/A N=34 The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients With Interstitial Lung Disease
Interstitial Lung Disease · Idiopathic Pulmonary Fibrosis · Interstitial Pneumonitis
Primary: Change in 6-minute Walk Test Distance (6MWD) — 46.5; 23.2 Meters
N/A N=130 Impulse Oscillometry Measurements in Severe Eosinophilic Asthmatics Before and After Anti-IL-5 Factor Initiation
Severe Asthma
Primary: Airway Resistance at 5 Hz (R5) at Baseline (Pre-mepolizumab Initiation) — 0.51; 0.39; 0.43 kPa/L/s
N/A N=450 A New Insertion Technique for Laryngeal Mask Airway
Airway Morbidity
Primary: Number of Subjects Who Present With Postoperative Sore Throat — 71; 71; 67 Participants
Phase 2 N=119 OBS in Adolescent and Adults With EOE: A Phase II, Randomized, Double-Blind, Placebo Controlled, Study With an Open Label Extension
Eosinophilic Esophagitis (EoE)
Primary: Percent of Participants Who Were Histologic Responders — 2.6; 38.8 percent of participants — p=<0.0001
Phase 3 N=38 Efficacy of Albuterol SPIROMAX® in Adult and Adolescent Patients With Exercise-Induced Bronchoconstriction (EIB)
Exercise-Induced Bronchoconstriction (EIB)
Primary: Maximum Percentage Fall From Baseline in Forced Expiratory Volume in 1 Second (FEV1) up to 60 Minutes After the Exercise Challenge — 6.21; 22.38 percentage change from…
N/A N=24 Novel by Upper Airway Respiratory Muscle Training to Treat OSA in Chronic SCI
OSA · SCI/D · Upper Airway Exercise
Primary: Feasibility-Number of Participants Who Complete the Three-month Protocol — 8; 10 Participants
Phase 2 N=18 PEEP as Rescue Therapy for Asthmatics With Elevated BMI
Asthma
Primary: Central and Peripheral Elastance — 391; 461; 587; 334 cmH2O/L
N/A N=134 Longitudinal Follow-up of High School Athletes
Elite Athlete · Healthy
Primary: Maximal Fall in Forced Expiratory Volume in One-second (FEV1) After Eucapnic Voluntary Hyperventilation (EVH) Test — -4; -9; -9; -5 percentage of change in FEV1 after…
Phase 4 N=74 Crossover Study Comparing Fluticasone Furoate (FF)/Vilanterol (VI) Once Daily Versus Fluticasone Propionate (FP) Twice Daily in Subjects With Asthma and Exercise-Induced Bronchoconstriction (EIB)
Asthma
Primary: Maximal Percent Decrease in Forced Expiratory Volume in One Second (FEV1) Following Exercise Challenge at 12 Hours (Hrs) Post Evening Dose From Pre-exercise FEV1…
N/A N=20 Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Laser Laryngeal Surgery
Otorhinolaryngologic Surgical Procedures · Laser Therapy
Primary: Lowest Intraoperative Peripheral Oxygen Saturation (SpO2) — 97; 97 percentage of oxygen — p=0.7934
N/A N=58 Voice Therapy With a Semi-occluded Vocal Tract
Voice Disorders
Primary: (Supra)Glottic Activity: Amplitude of Vibration — 37.7; 32.5; 28.8; 37.1 percentage
N/A N=15 Upper Airway Physical Therapy for the Treatment of Obstructive Sleep Apnea
Obstructive Sleep Apnea Syndrome
Primary: Delta of Apnea Hypopnea Index (AHI) as Measured by Polysomnography (PSG) — 4.27 events per hour
N/A N=20 Respiratory Muscle Strength Training in Presbyphonia
Presbylarynx
Primary: Post-Treatment Mean in Voice Handicap Index Score — 15.00; 15.75; 18.50 score on a scale — p=0.041
N/A N=24 The Effects of Respiratory Training on Voice
Muscle Tension Dysphonia
Primary: Post Training Lung Volume Initiation — 21.07; 27.04 % vital capacity relative to rest level — p=<0.0005
N/A N=55 Progression of Airway Obstruction in Childhood Asthma
Asthma
Primary: Airway Wall Thickness — 1.5; 1.5; 1.4; 1.6 mm — p=0.2
N/A N=20 Assessing the Impacts of a UESAD on Laryngeal Symptoms and Salivary Pepsin
Laryngopharyngeal Reflux
Primary: Salivary Pepsin Concentration — 158.4 ng/mL — p=0.61
N/A N=42 Fluticasone Versus Esomeprazole to Treat Eosinophilic Esophagitis
Eosinophilic Esophagitis
Primary: Number of Participants Who Responded — 7; 4 participants
Phase 2 N=42 Topical Steroid Treatment for Eosinophilic Esophagitis
Eosinophilic Esophagitis
Primary: Number of Participants With Complete Response to Dysphagia — 9; 6 participants — p=0.74
N/A N=84 Endotracheal Tube Versus Laryngeal Mask Airway for Esophagogastroduodenoscopy
Airway Morbidity
Primary: Endoscopist Satisfaction — 1.0; 1.1 units on a scale
N/A N=13 Effectiveness of Expiratory Muscle Strength Training for Improving Communication in ALS
Amyotrophic Lateral Sclerosis
Primary: Change From Baseline to Post-treatment for Maximum Expiratory Pressure — 66.10; 83.75 cmH2O — p=.001
N/A N=131 Use of Laryngeal Mask Airway in Pediatric Adenotonsillectomy
Laryngeal Mask Airway · Tonsillectomy
Primary: Number of Participants With Laryngospasm — 8; 6 Participants