Clinical Trial Search

Primary: Numbers of Circulating Total EVs in Platelet-free Plasma (PFP) Detected by Nanoparticle Tracking Analysis (NTA) — -2.9*10^10; 7.5*10^9 vesicles per ml blood — p=<0.001

Primary: Concentration of Platelet Extracellular Vesicles/ml — 2690000; 4310000 Platelet Extracellular Vesicles/mL

Primary: miR-1 Abundance — 226; 110; 286 percent change

Primary: Evaluation of 60-day Mortality Rate — 10; 14; 16 Participants — p=0.1343

Primary: Number of Participants With Adverse Reaction (AE) and Severe Adverse Reaction (SAE) — 1; 0; 0; 0 Participants

Primary: In Vitro Lipoprotein Functions — 20.8; 26.5 Percentage of cholesterol content

Primary: Mitochondrial Function in Circulating Cells and Muscle Tissue in Young Women — 26.48; 30.46; 120.04; 140.43 pmol O2/min per 400K cells

Primary: Cholesterol Efflux Capacity (CEC) — 1.30; 0.65 Ratio

Primary: In Hospital Mortality — 0; 4 participants — p=0.142

Primary: Pulmonary Vascular Resistance — 153.8; 213.0; 174.6; 123.5 dyne*second/centimeter˄5 — p=<0.05

Primary: Total Number of Inflammatory Cells Recovered in Sputum — 2.3; 2.1; 1.9; 5.2 10^6 cells/ml — p=0.1

Primary: Myocardial Perfusion at Rest — 55; 135 IU/s

Primary: Change in Late Outgrowth Endothelial Progenitor Colonies — 0.3; 0.2; 3.1; 0.1 LOEPC colonies — p=<0.05

Primary: Percentage Flow-Mediated Dilation (FMD) — 5.64; 5.32; 6.29; 7.21 percentage of change in FMD

Primary: Change in Inflammation Surface Area. — 100; 100; 43; 135 percentage of the baseline surface

Primary: Coronary Endothelial Function as Assessed by Percent Coronary Artery Area Change With Isometric Handgrip Exercise — 5.6 percent change in coronary artery area

Primary: Change in Mitochondrial Network Complexity of Endothelial Cells as Measured by Mitochondrial Network Fragment Ratio