N/A N=10 FDG PET/MRI Evaluation of Facet Joint Pain
Low Back Pain
Primary: Facet Joint High Grade FDG Activity Concordance to Pain — 0.10 concordance correlation coefficient
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=39 A Prospective Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves Versus Facet Joint Injection of Corticosteroid for the Treatment of Lumbar Facet Syndrome
Lumbar Facet Syndrome
Primary: Numeric Pain Rating Scale (NPRS) — 14; 3 Participants
N/A N=120 Effectiveness of Lumbar Facet Joint Nerve Blocks
Low Back Pain
Primary: Average Numeric Rating Scale — 8.2; 7.9; 3.8; 3.5 units on a scale — p=>0.05
Phase 2 N=75 Safety and Efficacy of XT-150 for Facet Joint Osteoarthritis Pain
Facet Joint Pain · Back Pain · Inflammation
Primary: Number of Participants Reporting Serious Adverse Events (SAEs) and Non-SAEs — 11; 12; 14; 14 Participants
N/A N=151 Efficacy and Cost: Benefit Ratio of 0, 1, and 2 Medial Branch Blocks for Lumbar Facet Joint Radiofrequency Denervation
Low Back Pain
Primary: Cost Per Successful Procedure — 15,241; 17,142; 6286 U.S. dollars
N/A N=120 Effectiveness of Cervical Facet Joint Nerve Blocks
Neck Pain
Primary: Numeric Rating Scale (NRS) — 8.2; 8.2; 3.5; 3.2 units on a scale — p=<0.05
N/A N=100 Effectiveness of Thoracic Facet Joint Nerve Blocks
Low Back Pain
Primary: Numeric Rating Scale — 7.9; 7.8; 3.1; 3.1 units on a scale — p=0.964
N/A N=30 Cryoneurolysis for Facet Mediated Chronic Low Back Pain
Low Back Pain · Facet Joint Pain
Primary: Safety of Cryoneurolysis as Compared to Radiofrequency Ablation (RFA) — 0; 0 Participants
N/A N=390 A Pivotal Study of a Facet Replacement System to Treat Spinal Stenosis
Lumbar Spinal Stenosis
Primary: Measure of Pain/Disability Using the Zurich Claudication Questionnaire (ZCQ) Physical Function Score — 1.7; 1.6; 1.7 score on a scale
N/A N=6 Safety of Spine Radiofrequency Procedures
Radiofrequency Ablation in Patients With Spinal Hardware
Primary: Number of Procedures in Which Temperature of Screws Increased — 4; 2 procedures
Phase 4 N=23 Lazanda Fentanyl Nasal Spray Pre Radiofrequency Nerve Ablations(RFA) of Lumbar Facet Joints
Minor Procedural Pain
Primary: Safety and Tolerability as Measured by the Number of Adverse Events — 0 adverse events
N/A N=188 Efficacy of DBM Fasciatherapy for Patients Suffering From Chronic Low Back Pain
Low Back Pain
Primary: Pain Intensity — 4.2; 4.1; 4.0 score on a scale
Phase 4 N=122 Fascia Iliaca Blocks for Pain Control After Total Hip Arthroplasty
Arthritis of Hip
Primary: Averaged Pain Score — 3.75; 4.11 score on a scale
N/A N=8 Technical Efficacy of a Direction Specific Radiofrequency Device in the Performance of Lumbar Medial Branch Neurotomies
Low Back Pain
Primary: Percentage of Patients With Magnetic Resonance Imaging (MRI) Evidence of Tissue Ablation/Edema at Targeted Lumbar Medial Branches — 100 percentage of participants
Phase 4 N=60 Ultrasound Guided Trigeminal Nerve Block for Typical or Atypical Facial Pain
Typical Facial Pain · Atypical Facial Pain
Primary: The Proportion of Subjects Reporting at Least 50% Overall Pain Relief — 19; 14; 10; 16 Participants — p=.196
N/A N=25 MONOVISC for Hip Joint Pain Relief Due to Osteoarthritis
Osteoarthritis, Hip
Primary: Numerical Rating Scale (NRS) Pain on Walking — -3.68 score on a scale — p=<0.0001
N/A N=2 Focal Pain Outcomes Using Configurations Applied for Lateral Stimulation
Chronic Pain
Primary: Change in Pain Intensity — 5; 4.5; 4.5; 1 units on a scale
N/A N=200 Prevalence of Femoroacetabular Impingement in Asymptomatic Patients
Femoroacetabular Hip Impingement Syndrome
Primary: Prevalence of Femoroacetabular Impingement (FAI) — 28; 172 Participants
N/A N=80 Knee Bracing for People With Patellofemoral Osteoarthritis
Knee Osteoarthritis
Primary: Change in Pain on the VIsual Analog Scale (VAS) — -.068 change in units on a scale from baseline
Phase 2 N=222 PF-06372865 In Subjects With Chronic Low Back Pain
Chronic Low Back Pain
Primary: Change From Baseline in Daily Low Back Pain Intensity (LBPI) Score as Measured by an 11-point Numeric Rating Scale (NRS) at Week 4 — -1.19; -1.03; -1.45 units on a scale
Phase 4 N=84 Hip Scope Fascia-iliaca (FI) Block Study
Hip Dysplasia · Femoroacetabular Impingement · Acetabular Labrum Tear
Primary: Visual Analog Scale — 2.65; 2.50 units on a scale
Phase 2 N=436 Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee
Knee Osteoarthritis
Primary: Change in WOMAC A — -91.8; -110.0; -109.8; -93.7 units on a scale — p=<0.05
N/A N=71 Molecular Pathways Involved in Knee Pain
Knee Osteoarthritis · Knee Pain Chronic
Primary: Pain Sensitivity: Pressure Pain Detection Threshold (PPT) — 252.58; 266.17 kPa
Phase 3 N=5,331 Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip
Osteoarthritis of the Knee or Hip
Primary: Number of Participants With Any Treatment-Emergent Adverse Event (TEAE) — 1055; 840; 885; 185 Participants
N/A N=416 Flares of Low Back Pain With Activity Research Study
Low Back Pain
Primary: Participant-reported "Flares" of Low Back Pain (Aim 1) — 7.3 Mean flares per year
N/A N=25 MONOVISC for Shoulder Joint Pain Relief Due to Osteoarthritis
Osteo Arthritis Shoulders
Primary: Numerical Rating Scale (NRS) Pain — -4.12 score on a scale — p=<0.0001
N/A N=100 Associated Joint Pain With Controlled Ankle Movement (CAM) Walker Boot Wear
Pain · Ankle Injuries
Primary: The Presence and Severity of Secondary Site Pain — 31 Participants
Phase 3 N=82 A Trial of Corticosteroids for Low Back Pain
Radicular Low Back Pain
Primary: Numerical Rating Scale (0-10), an Interval Pain Scale, on Which 0 Indicates no Pain and 10 Indicates the Worst Pain Imaginable — 7.1; 5.8 units on a scale
Phase 4 N=421 Pain Increases After Shoulder Injection
Shoulder Pain
Primary: Incidence of a Flare Reaction — 44; 8; 149; 191 Person-visits
N/A N=148 Investigation of Sacroiliac Fusion Treatment (INSITE)
Degenerative Sacroiliitis · Sacroiliac Joint Disruption
Primary: Subject Success — 84; 12 Participants