Phase 2 N=175 Preventing Diabetic Foot Ulcers Through Cleaner Feet
Diabetic Foot Ulcer
Primary: Time to New Foot Complication Among All Randomized Participants — 12; 14 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=60 Metatarsal Phalangeal Joint Deformity Progression - R01
Diabetes Mellitus (DM)
Primary: Change in Metatarsal Phalangeal Joint Angle (Degrees) in People With Diabetes From Baseline and at a 3-year Period — 0.8; -0.1 degrees
Phase 2 N=30 Micro-mobile Foot Compression and Diabetic Foot
Diabetes · PAD · Lower Extremity Edema
Primary: Change in Balance From Baseline to 4 Weeks — 0.94; 0.76 cm
N/A N=99 Enhancing Diabetic Foot Education by Viewing Personal Plantar Pressures
Diabetes Mellitus · Diabetic Neuropathies · Foot Complications
Primary: Foot Care Behavior Score — 29; 36; 33; 42 Participants — p=0.0770
N/A N=84 Plantar Heel Pain: Multisegment Foot Motion and Muscle Function, FFI Translation, and Evaluation of Treatments
Plantar Fasciitis
Primary: Worst Pain — 5.96; 5.74; 3.91; 4.08 score — p=0.660
N/A N=182 Less Infections for the Diabetic Foot
Diabetic Foot
Primary: Number of Participants Experiencing Clinical Failure — 26; 30 Participants
Phase 2 N=16 Novel Offloading for Diabetic Foot Ulcers With PulseFlow: A Prospective Study
Diabetic Foot Ulcer · Offloading
Primary: Lower Extremity Perfusion Change From Baseline to 4 Weeks — 167; 75 percentage of baseline perfusion
N/A N=20 Improving DFU Outcomes: Early Detection of Foot Ulcers Using Novel Technology
Diabetic Foot Ulcer
Primary: Adherence to Use of SmartMat — 6.4 number of foot scans/week
Phase 3 N=68 Efficacy of the Combination of Isosorbide Dinitrate Spray and Chitosan in Diabetic Foot Ulcers
Diabetic Foot Ulcers
Primary: Biopsies — 2.46; 2.64; 2.56; 2.07 UI/dL
N/A N=28 Ankle-foot Orthoses for Peripheral Artery Disease
Peripheral Artery Disease
Primary: Change in WIQ Distance Subscore — 22.7; -7.2 Scale units
N/A N=30 Patient Specific 3D Printed Diabetic Insoles to Reduce Plantar Pressure
Diabetes
Primary: Plantar Pressure - Standard of Care — 202.71 kPa
N/A N=77 A Trial of Custom Foot Orthoses for the Treatment of Plantar Heel Pain
Plantar Fasciitis
Primary: Heel Pain — 26.3; 27.9; 26.6; 23.9 score on a survey — p=0.78
N/A N=974 Abnormal Plantar Pressure in Patients With Diabetes
Diabetes Complications
Primary: Abnormal Plantar Pressure Distribution — 80; 894 Participants
Phase 2 N=20 Nitric Oxide Releasing Solution (NORS) Footbath to Treat Athlete's Foot
Tinea Pedis
Primary: Number of Participants With Complete Cure: Post Treatment (Day 17) — 0; 4 Participants
Phase 3 N=707 Multicenter Study of the Safety and Efficacy of NAFT-500 in Tinea Pedis
Tinea Pedis · Athlete's Foot
Primary: Percentage of Subjects With Complete Cure at Week 6. — 17.7; 7.1; 16.1; 3.1 percentage of subjects with complete cur — p=0.010
N/A N=27 Multi-layer Insoles for a Patient-specific Approach to Shear and Pressure Reduction in Diabetes-related Foot Ulcer
Diabetic Foot Ulcer · Diabetic Foot
Primary: Plantar Foot Temperature Changes in Regions-of-interest in Response to Walking — 0.758; 0.272 Absolute change in temperature degrees
N/A N=82 Development and Testing of a New Generation of Diabetic Footwear
Diabetes Complications · Diabetic Neuropathies
Primary: Postural Sway During Shod Standing — 4.3; 3.1 cm^2
Phase 3 N=290 Efficacy and Safety of Terbinafine Film Forming Solution in Patients With Tinea Pedis
Tinea Pedis
Primary: Effective Treatment Outcome (Direct Microscopy and Culture Negative and Total Signs and Symptom Score Less or Equal to 2) — 73; 10 participants
N/A N=20 Pressure Alternating Shoes
Foot Ulcer, Diabetic
Primary: Maximum Average Pressure at Baseline With Pressure Alternating Shoes, Right Foot (Before Any Cells Were Offloaded) — 118.5; 113.7; 96.6; 54.9 kPa
N/A N=3 Peak Plantar Pressures While Wearing a Carbon Fiber Off Loading Orthoses
Diabetes Mellitus · Peripheral Neuropathy · Orthotic Device
Primary: Peak Plantar Pressure — 75.3; 14.2; 14.5; 22.8 Newtons per squared centimeters
N/A N=41 Neurogenic Inflammation in Diabetes
Diabetes Mellitus · Polyneuropathies · Arthropathy, Neurogenic
Primary: Induration Size as a Response to Intracutaneous Candida Albicans. — 4; 6; 5; 4 millimeters — p=0.84
N/A N=10 Improving Walking in Peripheral Artery Disease
Peripheral Artery Disease
Primary: Changes in Walking Distance After Three-months Intervention — 289.68; 262.95 meters
N/A N=604 Diagnostic Tools to Establish the Presence and Severity of Peripheral Arterial Disease in People With Diabetes
Diabetic Foot · Peripheral Arterial Disease · Diabetic Foot Ulcer
Primary: Diagnostic Accuracy — 36; 42; 55; 41 percentage
N/A N=381 Therapeutic Stockings to Prevent Foot Ulcers
Diabetes
Primary: Number of Participants Who Developed Foot Ulcer During Study Time Frame — 76; 82 Participants
Phase 3 N=40 Efficacy and Safety of Efinaconazole 10% Solution in the Treatment of Onychomycosis in Diabetic Patients
Onychomycosis
Primary: Primary Endpoint - Efficacy — 4 Participants
N/A N=80 Polyurethane Foam on the Heel for Prevention in Children
Flat Foot · Pressure Ulcer
Primary: Heel Pressure Sores (Numbers of Participants With Heel Pressure Sores) — 17; 21 Participants
Phase 3 N=860 Evaluation of the Efficacy and Safety of NAFT-600 in Subjects With Tinea Pedis
Tinea Pedis
Primary: Complete Cure of Interdigital Tinea Pedis — 26.0; 3.3 percentage of subjects — p=<0.025
N/A N=225 Instant Total Contact Cast to Heal Diabetic Foot Ulcers
Diabetic Foot Ulcers
Primary: Number of Participants Who Achieve Full Wound Healing. — 35; 63; 37 Participants
Phase 3 N=139 PinPointe FootLaser for the Treatment of Onychomycosis
Infected Toenails · Onychomycosis
Primary: Nail Bed Clearing
Phase 2 N=38 Safety and Efficacy Study of TG-873870 (Nemonoxacin) in Diabetic Foot Infections
Diabetic Foot Infections
Primary: Clinical Success (in ITT Population) — 95.7 percentage of participants