N/A N=172 Durability of Adherence in Self-Management of HIV
HIV Infections
Primary: Mean Self-reported Adherence Score (%) Over a One-month Recall — 97.5; 98.2 percentage of adherence score — p=0.52
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=594 Improving Treatment Adherence in HIV-Infected Individuals
HIV Antiretroviral Therapy (ART) Adherence · Health Behavior
Primary: AIDS Clinical Trials Group (ACTG) 3-day Recall Measure of Doses Taken — 72.89; 75.46; 74.86; 77.33 percent with 100% adherence — p=0.12
N/A N=51 SteadyRx: Smartphone ART Adherence Intervention for Drug Users
HIV · Medication Adherence
Primary: Medication Adherence as Assessed by the Medication Event Monitoring System (MEMS) Cap — 52.2; 27.2 percentage of participants
N/A N=130 Measuring and Monitoring Adherence to ART With Pill Ingestible Sensor System
HIV/AIDS · Medication Adherence
Primary: Adherence Measured by Sensor by Percentage of Prescribed Medications Taken — 87.5 percentage of prescribed medication
N/A N=63 HIV Adherence Bottle Intervention Trial
HIV-1-infection · Adherence, Medication
Primary: Change in Tenofovir Diphosphate (TFV-DP) Drug Levels — 1230; 1108; 1887; 1084 fmol/punch — p=0.070
N/A N=60 Care4Today v2.0 Application for Improving Adherence to HIV Medications
HIV · AIDS
Primary: Number of Participants ≥90% Adherent to Antiretroviral Medication Based on MEMS Cap Openings — 9; 5 Participants — p=0.32
N/A N=512 Adherence Support Intervention for Persons Living With HIV/AIDS (PLWHA) on Antiretroviral Therapy (ART) in Estonia
HIV · AIDS · Medication Adherence
Primary: Antiretroviral Therapy (ART) Adherence (Self-reported 3-day Recall Measure) — 142; 139; 6; 12 participants
N/A N=40 Depression and ART Adherence in HIV+ Latinos
Depressive Symptoms · HIV Infections
Primary: Depression From (1) Clinician-Administered MADRS Measure, and (2) Participant Self-Report Ratings With BDI-1a — 17.8; 19.2; 19.7; 17.7 Units on a scale
N/A N=257 Determining the Effects of Observed and Self-Administered Drug Regimens in HIV Infected Adults
HIV Infections
Primary: Confirmed Virologic Failure at or Prior to Week 48 — 95; 105; 34; 23 participants — p=0.133
N/A N=106 Secondary HIV Prevention and Adherence Among HIV-infected Drug Users
Risk Behavior · Medication Adherence · HIV
Primary: Number of Participants in Each Condition With Optimal ART Adherence — 27; 29 participants
N/A N=68 China Antiretroviral Treatment Adherence for Life
HIV Infections
Primary: Mean Adherence, as Measured by Electronic Drug Monitors (EDM) — 96.5; 84.5; 96.4; 84.1 percentage of doses taken on time
N/A N=89 Triggered Escalating Real-time Adherence (TERA) Intervention
HIV Infections
Primary: Percentage of Participants With Plasma Human Immunodeficiency Virus - Type I Ribonucleic Acid (HIV-1 RNA) Levels Less Than (<) 50 Copies/mL at Week 12 — 24.4; 20.9…
N/A N=200 Urine Tenofovir Point-of-care Test to Identify Patients in Need of ART Adherence Support (UTRA Study)
Risk Reduction
Primary: Proportion of Participants in Each Arm Achieving Viral Suppression to <50 Copies/ml — 59; 48 Participants
N/A N=7 Automated Medication Platform With Video Observation and Facial Recognition to Improve Adherence to Antiretroviral Therapy in Patients With HIV/AIDS
HIV Infections
Primary: Rate of Medication Adherence — 2; 1 Participants
N/A N=78 Project SMART Automated Pillbox Study
HIV/AIDS · Cocaine Use
Primary: Adherence to Anti-Retroviral Therapy (ART) at the End of 12-Week Intervention Period — 91.07; 96.00; 99.82; 94.81 percentage of times pills taken
N/A N=63 Real-Time Antiretroviral Therapy Adherence Intervention in Uganda
HIV/AIDS · Adherence
Primary: Antiretroviral Therapy (ART) Adherence Levels — 91; 79; 79 Percent adherence — p=<0.05
N/A N=58 Texting to Improve Adherence in HIV+ With Bipolar Disorder
HIV Disease · Bipolar Disorder
Primary: Proportion Adherent to ARV and Psychotropic Medication by Electronic Monitoring System (MEMS) — 90.3; 90.0; 83.9; 90.0 percentage of taken doses — p=0.95
N/A N=75 Personalized Text Messages to Improve Antiretroviral Treatment (ART) Adherence in HIV+ Methamphetamine Users
HIV · AIDS
Primary: Overall MEMS Adherence to Antiretroviral Medication — 68.0; 70.4 percentage of taken doses — p=0.68
N/A N=43 Adherence to HIV Treatment Postpartum: The Implications of Transitions Among Women Living With HIV in South Africa
HIV · Pregnancy Related
Primary: Feasibility of the Intervention - Number of Counseling Sessions — 2.92; 1 sessions
N/A N=28 Youth Ending the HIV Epidemic
HIV/AIDS · Mobile Health · Young Adults
Primary: Feasibility: Rate of Participant Retention — 22 Participants
N/A N=60 Use of Antiretroviral (ARV) Drug Levels in Dried Blood Spots (DBS) to Assess and Manage ART Adherence in South Africa
Therapeutic Adherence and Compliance
Primary: TFV-diphosphate (TFV-DP) Drug Level — 1377.82; 1156.79 fentomole/punch — p=.014
N/A N=158 Improving Adherence to Smoking Cessation Medication Among PLWHA
Tobacco Use Cessation
Primary: End-of-intervention Varenicline Adherence — 18; 16; 15 participants
N/A N=212 The Effectiveness of SMS in Improving Antiretroviral Medication Adherence Among Adolescents Living With HIV in Nigeria
HIV Infections
Primary: ART Adherence at 20 Weeks as Determined by VAS, Viral Load — 57; 47; 63; 46 Participants
N/A N=60 Adherence Connection for Counseling, Education, and Support (ACCESS) II
HIV Infections
Primary: Self-Reported ART Adherence — 56.67; 58.7 Percentage of successful doses
N/A N=216 Treatment Advocacy Intervention for HIV-Positive African Americans
HIV
Primary: Medication Adherence — 77.96; 80.13; 64.87; 76.13 Percentage of doses taken — p=.005
N/A N=16,660 Home Assessment and Initiation of Antiretroviral Therapy for HIV in Malawi
HIV
Primary: ART Initiation — 181; 63 participants
N/A N=32 mHealth Intervention Supporting HIV Treatment Adherence and Retention
HIV · Adherence · Retention
Primary: Number of Particpatns Who Considered the Intervention Feasible and Acceptable — 20 participants
Early Phase 1 N=14 Project ADHERE: Clinical Proof-of-Concept of a Tenofovir (TFV) Aptamer-Based Biosensor
HIV/AIDS · Adherence, Medication · Drug Use
Primary: Baseline TFV (Tenofovir) Levels in Plasma
N/A N=149 Music for Health Project
Human Immunodeficiency Virus
Primary: Change in Antiretroviral Therapy (ART) Adherence Rates — 27.04; 26.25; 26.14; 26.48 score on a scale
N/A N=83 Adherence Interventions for HIV Youth Via Text & Cell Phone - Sequential Multiple Assignment Randomized Trial (SMART)
HIV Infections
Primary: Undetectable Viral Load — 58.8; 62.9; 89.5; 87.5 percentage of participants