Phase 4 N=25 Treating Hearing Loss to Improve Mood and Cognition in Older Adults
Hearing Loss · Depression
Primary: Hamilton Rating Score for Depression (HRSD) — 12.04; 13.86 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=34 Longitudinal Outcomes of Hearing Aids
Presbycusis
Primary: Hearing Aid Benefit as Measured by the Glasgow Hearing Aid Benefit Profile (GHABP) — 3.68; 3.55; 3.63 score on a scale
N/A N=129 Hearing Loss Prevention for Veterans
Hearing Loss, Noise-Induced
Primary: Percentage of Time Spent at Sound Levels >80 Decibels — 4.4; 5.0; 6.3 percentage of time — p=0.289
Phase 2 N=23 FX-322 in Sensorineural Hearing Loss
Sensorineural Hearing Loss
Primary: Number of Participants With Treatment-emergent Adverse Event(s) (TEAEs) — 2; 3; 5; 6 Participants
Phase 2 N=72 Micronutrients to Prevent Noise-induced Hearing Loss
Noise-Induced Hearing Loss
Primary: Average Threshold Shift at 4 kHz in Both Ears — 3.94; 3.4; 2.77; 2.03 decibels — p=0.58
N/A N=38 Age-related Hearing Loss and Lexical Disorders
Alzheimer Disease · Presbycusis · Lexical Syntactic Disorder
Primary: Link Between Lack of Word and Presbycusis — 38; 38.5; 23; 21.5 score on a scale
N/A N=24 Benefits of the HiResolution Bionic Ear System in Adults With Asymmetric Hearing Loss
Hearing Loss · Ear Diseases · Hearing Disorders
Primary: Change in Consonant Nucleus-Consonant (CNC) Word Recognition Test (Implanted Ear Only) — 2.13; 61.14 percentage of recognized words
N/A N=151 Baltimore HEARS: Hearing Health Equity Through Accessible Research & Solutions
Age-related Hearing Impairment 1 · Personal Communication
Primary: Change From Baseline in Hearing Handicap Inventory for the Elderly (HHIE-S) — -13.2; .06 score on a scale
N/A N=27 Audiobooks for Hearing Loss App as Auditory Training
Hearing Loss · Hearing Impaired Children · Hearing Impairment
Primary: Audiobooks Efficacy: Change in Slope of Curve for SNR Loss Scores on a Scale/Week for Partial BKB-SIN Hearing Test — 5.978; 5.889; 5.757; 5.600 units on a scale/week…
N/A N=65 Feasibility and Acceptability of Using Low-Gain Hearing Aids for Bothersome Tinnitus
Tinnitus · Hearing Aids · Normal Hearing
Primary: Tinnitus Functional Index Change — 53.31; 44.10; 64.93 units on a scale
N/A N=320 Wide Frequency Band Test of Hearing in Veterans
Hearing Loss, Sensorineural · Hearing Loss, Conductive · Hearing Loss, Mixed Conductive-Sensorineural
Primary: Experimental Middle Ear Test: Ambient Wideband Absorbance — 0.39; 0.38; 0.32 Ratio
N/A N=40 Cochlear Implantation in Adults With Asymmetric Hearing Loss Clinical Trial
Hearing Loss
Primary: Change in Poor Ear Alone CNC Monosyllabic Word Understanding in Quiet — 0.09; 0.53; 0.44 percentage of words correct — p=<0.001
N/A N=45 Interaural Frequency and Loudness Mismatch in SSD CI Users
Outcomes
Primary: Speech Understanding in Noise, Measured With the R-Space Test Environment. The R-Space Test Environment Simulates Speech Understanding in a Noisy Restaurant. — -3.0…
N/A N=290 Impact of Hearing Aid Service-delivery Model and Technology on Patient Outcomes
Presbycusis
Primary: Hearing Aid Use Measured Using In-situ Glasgow Hearing Aid Benefit Profile (EMA-GHABP-Use) — 4.4; 4.1; 3.8; 4.5 score on a scale
Phase 2 N=142 FX-322 in Adults With Acquired Sensorineural Hearing Loss
Hearing Loss, Sensorineural · Noise Induced Hearing Loss · Sudden Hearing Loss
Primary: Word Recognition in Quiet — 14.7; 11.1 Percent of subjects — p=0.525
Phase 2 N=95 FX-322 in Adults With Stable Sensorineural Hearing Loss
Sensorineural Hearing Loss · Noise Induced Hearing Loss · Sudden Sensorineural Hearing Loss
Primary: Word Recognition in Quiet — 23.8; 16.7; 15.8; 18.8 Percent — p=0.068
N/A N=19 Hearing Aid Quality and Reliability Study
Hearing Loss
Primary: Electroacoustic Evaluation of Hearing Aids in Accordance With Manufacturer Specifications, Day 1 — 38; 0 hearing aid devices
N/A N=107 Sensory Integration of Auditory and Visual Cues in Diverse Contexts
Vestibular Disorder · Hearing Loss, Sensorineural
Primary: Root Mean Square Velocity Anterior-posterior [AP] in cm/s (RMSV) — 3.59; 3.30; 3.07 cm/s — p=0.005
N/A N=18 PC-Based Rehabilitation of Auditory Function
Hearing Loss, Sensorineural
Primary: .Speech Discrimination Ability — 9.43; 0.46 signal to noise ratio in dB SNR
Phase 1 N=30 Auditory Training and Hearing Aid Satisfaction
Hearing Impairment, Sensorineural
Primary: Change in Hearing Aid Satisfaction After Auditory Training — 1.9; 1.7 units on a scale — p==0.269
N/A N=226 Blast Exposed Veterans With Auditory Complaints
Hearing Impairment · Hearing Aid Fitting
Primary: Hearing Handicap Inventory for Adults (HHIA) — 26.20; 37.34; 19.21 Scale score — p=.05
N/A N=18 Noise Reduction Preferences in Teenagers and Pre-teens
Hearing Loss
Primary: Subjective Rating of Listening Effort Questionnaire — 44.73; 44.5; 41.53; 35.86 units on a scale — p=0.007
Phase 2 N=135 Clinical Trial of the "Living Well With Hearing Loss Workshop"
Hearing Loss · Stress
Primary: Communication Profile for Hearing Impaired: Maladaptive Strategies Subscale — 0.33; 0.37 score on a scale — p=0.69
Phase 1 N=16 Wide-Bandwidth Open Canal Hearing Aid For Better Multitalker Speech Understanding
Hearing Impairment
Primary: Maximum Effective Sound Pressure Level (MEPO) — 95 decibels (dB) Sound Pressure Level (SPL)
N/A N=68 Clinical Validation of the Lexie Lumen Hearing Aid
Hearing Loss
Primary: Abbreviated Profile of Hearing Aid Benefit (APHAB) — 30.1; 21.4 score on a scale (1-99)
N/A N=36 Optimizing Soft Speech Recognition in Children With Hearing Loss
Hearing Loss, Sensorineural · Hearing Loss, Bilateral
Primary: Speech Recognition in Quiet Using CNC (Consonant-Nucleus-Consonant) Word Lists — 6.06; 53.7; 66.61; 69.7 percentage of correctly repeated words — p=.005
Phase 2 N=28 Phase I/IIa Study Evaluating Safety and Efficacy of an Intratympanic Dose of PIPE-505 in Subjects With Hearing Loss
Sensorineural Hearing Loss
Primary: Safety: Treatment-Emergent Adverse Events (TEAE) — 13; 5 Participants
N/A N=106 Promoting Early Diagnosis of Congenital Hearing Loss With Patient Navigators
Congenital Hearing Loss
Primary: Number of Participants Who do Not Receive Diagnostic Audiological Testing (Aim 1) — 15; 8 Participants
N/A N=1,098 Communities Helping the Hearing of Infants by Reaching Parents
Congenital Hearing Loss
Primary: Number of Participants Who do Not Receive Diagnostic Audiological Testing (Aim 1) — 378; 336 Participants
N/A N=37 Use of Amplification in Children With Unilateral Hearing Loss
Unilateral Hearing Loss
Primary: HEAR-QL 26 Questionnaire — 69.61; 74.05; 71.04; 80.21 score on a scale