Phase 2 N=120 Addressing Heavy Alcohol Use Consumption With Kudzu
Alcohol Use Disorder · Sexually Transmitted Diseases
Primary: Number of Binge Drinking Days — 2.15; 2.15; 1.94; 2.21 number of days
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=591 Using Counter Attitudinal Advocacy to Change Drinking Behavior
Alcohol Drinking · Alcohol Abuse
Primary: Drinks Per Week as Assessed by the Daily Drinking Questionnaire — 6.8; 6.0; 7.1 drinks per week — p=.646
Phase 2 N=212 Residual Effects of Intoxication on Student Performance
Alcoholic Intoxication · Neurobehavioral Manifestations
Primary: Self-reported Residual Effects of Heavy Drinking — 4.3; 1.93 scores on a scale
Phase 2 N=130 Levetiracetam XR in Very Heavy Drinkers
Alcoholism
Primary: The Percentage of Subjects With no Heavy Drinking Days During Study Weeks 5 Through 14. — 18.2; 14.1 percentage of subjects
Phase 2 N=236 Improving Smoking Cessation Outcomes in Heavy Drinkers - 1
Tobacco Use Disorder
Primary: Smoking Abstinence at 26 Weeks — 21; 22 participants — p=>.05
N/A N=99 Alcohol Intervention for First Year College Students
Underage Alcohol Use
Primary: Acceptability-Number of Participants Who Found the Study Overall Favorable — 38; 0 Participants
Phase 2 N=46 Varenicline to Reduce Alcohol Consumption in Heavy Drinkers
Alcohol Drinking
Primary: Alcohol Consumption — 92.0; 77.3 mg/%
N/A N=30 Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) Signaling
Alcohol Consumption
Primary: Change in Bile Salt Metabolism (C4 )Levels to Determine Effect of FXR
N/A N=365 Protective Behavioral Strategies and Brief Alcohol Interventions
Alcohol Consumption
Primary: Drinks Per Week — 12.55; 9.57; 13.74 drinks per week
Phase 1 N=537 Alcohol Health Education Among College Drinkers
College Student Drinking
Primary: Alcohol Consumption — 16.929; 17.988; 18.039 drinks
N/A N=37 Biobehavioral Pathways Underlying Alcohol Use and Health
Alcohol Use Disorder · Liver Diseases
Primary: Percentage of Screen Eligible Who Enroll — 28; 5 Participants
N/A N=31 Understanding and Intervening With Heavy Drinking Among Patients With HIV and HCV
Alcohol Use Disorder · HIV/AIDS · Hepatitis C
Primary: Mean Drinks Per Drinking Day Measured Using Timeline Follow Back (TLFB) at 60 Days. — 2.61; 5.49 Drinks per drinking day
N/A N=148 Brief Therapy Intervention for Heavy/Hazardous Drinking in HIV-Positive Women
HIV Infections · Alcoholism
Primary: Number of Drinking Days Out of the Past 90 Days — 34.03; 30.45; 13.58; 20.22 days — p=<0.005
N/A N=16 Pilot Study on Training Emerging Adults Skills in Navigating College
Alcohol Abuse · Cognitive Deficit in Attention
Primary: Participant Retention — 85.71; 88.89 percentage of participants
Phase 4 N=140 Naltrexone for Heavy Drinking in Young Adults
Alcohol Consumption · Alcoholic Intoxication · Alcoholism
Primary: Frequency of Heavy Episodic Drinking — 34.3; 33.4 percentage of heavy drinking days
Phase 2 N=150 ABT-436 for Alcohol Dependence
Alcohol Dependence · Alcohol Abuse · Alcohol Use Disorders
Primary: Weekly Percentage of Heaving Drinking Days — 37.6; 31.3 weekly percentage of heavy drinking days
Phase 2 N=200 Varenicline for Alcohol Dependence
Alcoholism
Primary: Weekly Percentage of Heavy Drinking Days — 37.9; 48.4 percentage of heavy drinking days
N/A N=200 Feasibility and Effectiveness of a Specialized Brief Intervention for Hazardous Drinkers in an Emergency Department.
Alcohol Drinking
Primary: Proportion of Risky Drinkers Measured by AUDIT-C — 20; 39 Participants
N/A N=134 Records for Alcohol Care Enhancement
Alcohol Use Disorder (AUD)
Primary: Percent of New Alcohol Use Disorder (AUD) Diagnosis Episodes That Meet Criteria for AUD Treatment Engagement Among Patients With a New AUD Diagnosis Who Are Empaneled to…
N/A N=38 Alcohol and Neural Cardiovascular Control in Binge Drinkers
Binge Drinking
Primary: Sympathetic Nerve Activity Burst Frequency — 18; 20 Burst/Min — p=0.283
Phase 4 N=142 Dutasteride Treatment for the Reduction of Heavy Drinking in Men
Alcoholism · Alcohol Abuse · Alcohol Dependence
Primary: Heavy Drinking Days Per Week — 1.75; 2.67 heavy drinking days/week — p=0.002
Phase 3 N=155 Dutasteride Treatment for Reducing Heavy Drinking in AUD: Predictors of Efficacy
Alcohol Use Disorder
Primary: Change in Heavy Drinking Days Per Week for Dutasteride vs. Placebo Groups — -2.24; -1.41 Heavy Drinking Days per week — p=0.012
N/A N=240 Interventions for Unemployed Hazardous Drinkers
Unemployment · Hazardous Drinking
Primary: Longest Duration of Alcohol Abstinence (Samples) (Physiological Measure) — 6.0; 11.0; 7.0; 7.5 number of alcohol negative breath tests — p=.028
Phase 4 N=120 High Dose Vitamin B1 to Reduce Abusive Alcohol Use
Alcoholism
Primary: Change in Average Daily Alcohol Consumption — -3.4; -3.0 alcoholic drinks per day
N/A N=120 Coping Skills for Alcohol Use
Alcohol Drinking · Coping Skills
Primary: Alcohol Use-Peak Drinks — 4.71; 4.79 number of drinks — p=>.05
Phase 2 N=64 Examining Alcohol Consumption, Perceptions, and User Experience of Alcohol Moderation Strategies
Alcohol Abuse · Alcohol Use Disorder · Alcohol Abuse, Episodic
Primary: The Young Adult Alcohol Consequences Questionnaire — -4.48; -4.63 outcome score minus baseline score
N/A N=119 Development and Pilot Testing of a Multimodal Web-based Program to Address Heavy Drinking During Smoking Cessation
Smoking Cessation · Alcohol Drinking
Primary: Number of Participants Who Reported 7-day Point-prevalence Smoking Abstinence at 1 Month — 10; 10 Participants — p=.90
Phase 2 N=60 Do Treatments for Smoking Cessation Affect Alcohol Drinking?
Alcohol Drinking
Primary: Number of Drinks Consumed — 2.1; 2.05; 1.5; 1.7 number of drinks
Phase 2 N=156 Seroquel for Frequent, Heavy Drinkers
Alcoholism
Primary: TimeLine Follow Back (TLFB) to Measure Percent Heavy Drinking Days During the Medication/Placebo Phase — 20; 24 percent days of heavy drinking — p=.388
N/A N=27 Digital Interventions to Treat Hazardous Drinking
Hazardous Drinking · Stress
Primary: Change in Alcohol Use (Quantity) — 15.4; 8.5; 7.5 drinks per week — p=<0.001