N/A N=214 Hypotension Prediction Index for Blood Pressure Management
Intraoperative Hypotension
Primary: Time- Weighted Average (TWA) MAP Under a Threshold of 65 mmHg. — 0.14; 0.14 mmHg — p=0.757
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=150 Fluid Responsiveness Evaluation in Sepsis-associated Hypotension
Sepsis · Hypotension
Primary: Fluid Balance — 0.65; 2.02 Liters — p=0.021
Phase 1 N=20 Intravenous AII for the Treatment of Severe Hypotension in High Output Shock: A Pilot Study
Septic Shock
Primary: Standing Dose of Norepinephrine Which is Required to Maintain a Mean Arterial Pressure (MAP) of 65 mmHg - Hour 1 — 7.4; 27.6 mcg/min
Phase 4 N=337 Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation
Acute Respiratory Failure · Intubation Complication
Primary: Number of Participants With Cardiovascular Collapse — 33; 31 Participants
N/A N=71 Hemodynamically Guided Home Self-Therapy in Severe Heart Failure Patients (HOMEOSTASIS)
Heart Failure
Primary: Number of Patients Free From Major Adverse Cardiac and Neurological Events (MACNE) at 6 Weeks. — 51 Participants
Phase 2 N=47 Efficacy Study of a Facemask Device to Treat Hypotension
Hypotension
Primary: Rise in Systolic Blood Pressure Over the First 10 Minutes of Use Compared to Baseline — 5.9; 12.9 mm Hg
Phase 4 N=24 Atrial Fibrillation Without Hemodynamic Instability in the Intensive Care Unit
Atrial Fibrillation
Primary: Conversion From Atrial Fibrillation to Sinus Rhythm — 8; 5 participants
N/A N=20 A Net Ultrafiltration Challenge to Predict Preload-dependence (UF CHALLENGE)
Acute Kidney Injury
Primary: Diagnostic Performance of the Net Ultrafiltration (UF NET) Challenge to Detect de Novo Preload Dependence — 0.74 Proportion probability (0 to 1) — p=0.02
N/A N=139 Trial of Dialysate Sodium in Chronic Hospitalized Hemodialysis Patients
Intra-dialytic Hypotension
Primary: Change in Intra-dialytic Decline in Systolic Blood Pressure — 26; 23 mm Hg
N/A N=65 Does Heart Rate Variablity (HRV) Predict Hypotension in Patients Undergoing Cervical Myelopathy Surgery ?
Heart Rate Variability
Primary: Heart Rate Variability (HRV) — 1439; 2191 ms2
Phase 2 N=191 Field Trial of Hypotensive Versus Standard Resuscitation for Hemorrhagic Shock After Trauma
Blunt Trauma · Penetrating Wound · Hemorrhagic Shock
Primary: Total Volume of All Crystalloid Given for Early Resuscitation (Feasibility) — 2.04; 1.04; 1 liters
N/A N=34 Hypotension Prediction Index to Predict Epidural-labor Analgesia Induced Hypotension
Anesthesia, Epidural · Hypotension
Primary: Time-to-treatment of Hypotension (Minutes) — 21.8; 23.1 minutes
Phase 3 N=100 Analyzing the Relationship Between Speed Propofol is Given and Low Blood Pressure
Hypotension on Induction
Primary: Patients Administered Propofol at a Slower Rate of Infusion Will Have Lower Incidence of Post Induction Hypotension Than Patients Administered Propofol at FDA Approved…
N/A N=40 Closed-Loop Fluid Administration System Using Hemodynamic Monitors
Intraoperative Volume Status · Postoperative Complications
Primary: Fluid Status During Surgery — 95 percentage of case time
N/A N=48 Hemodynamic Effects of Standard Cardiopulmonary Resuscitation (CPR), Active Compression Decompression CPR With an Inspiratory Impedance Device, and Standard CPR With an Intrathoracic Pressure Regulator During Out-of-hospital Cardiac Arrest
Cardiac Arrest · Sudden Cardiac Death
Primary: Mean Systolic and Diastolic Blood Pressures — 80.38; 121.21; 61.37; 15.52 mmHg
N/A N=429 Predict Fluid Responsiveness in Spinal Anesthesia
Hypotension and Shock · Excessive Amount of Blood / Fluid Infusion
Primary: Percentage of Participants With Systemic Hypotensions — 68; 46; 65 Participants
N/A N=17,463 Decision Support for Intraoperative Low Blood Pressure
Hypotension
Primary: Postoperative Acute Kidney Injury — 1333; 372; 9670; 2785 Participants
N/A N=15 Clinical Hemodynamic Study of Balloon Counterpulsation in Advanced Heart Failure
Heart Failure
Primary: Impact of Intra-aortic Balloon Pump Activation on Left Ventricular Stroke Work. — 939; 5628; 667; NA mmHg-mL
Phase 2 N=2 Washington Study of Hemofiltration After Out-of-Hospital Cardiac Arrest
Cardiac Arrest
Primary: Intervention Compliance — 1 participants
N/A N=95 Heart Rate Variability in Trauma Patients
Trauma
Primary: Base Deficit </= -6 — 12 participants
Phase 4 N=32 Angiotensin II in General Anesthesia
Hypertension
Primary: Median Dose Required to Increase the Systolic Blood Pressure (SBP) — 35; 43; 45 ng/kg/min
N/A N=406 National Cardiogenic Shock Initiative
Cardiogenic Shock · Acute Myocardial Infarction · STEMI - ST Elevation Myocardial Infarction
Primary: Number of Participants Who Survived at Discharge — 287 Participants
N/A N=14 Blood Volume Analysis of Total Hip Arthroplasty Patients Under Hypotensive Anesthesia
Blood Volume Analysis
Primary: Change in Total Blood Volume — 487 ml
Phase 3 N=321 A Phase 3 Study of LJPC-501 in Patients With Catecholamine-Resistant Hypotension
Catecholamine-resistant Hypotension (CRH) · Distributive Shock · High Output Shock
Primary: An Increased MAP, Defined as Achievement of a Day 1 MAP at 3 Hours Following the Initiation of Study Drug, of ≥ 75 mmHg OR a 10 mmHg Increase in Baseline MAP — 114; 37…
N/A N=68 Clinical Stabilization of Hypercapnia: NIPPV v HVNI
Hypercapnic Respiratory Failure · Chronic Obstructive Pulmonary Disease · Dyspnea
Primary: Rated Perceived Dyspnea [RPD] — 5.4; 5.6; 3.97; 4.54 units on a scale (0-10)
N/A N=10 Blood Volume and Fluid Kinetics in Patients Undergoing Extracorporal Circulation
Blood Volume, Extravasation
Primary: Blood Volume — 4.61 Litre
N/A N=14 Effects of Exercise Training on Fluid Instability in Heart Failure Patients
Heart Failure
Primary: Bioelectrical Impedance Change — 47.52; 47.1; 41.27; 46.8 Percentage of Extra Cellular Fluid
Phase 3 N=12 Hydrocortisone for Term Hypotension
Infant, Newborn, Diseases · Cardiovascular Insufficiency
Primary: Death — 6; 6; 0; 0 Participants
Phase 2 N=74 Glycemic Control and Variability for Congestive Heart Failure Exacerbation
Congestive Heart Failure · Diabetes Mellitus
Primary: Hospital Length of Stay — 7; 8 days
N/A N=356 Orthostatic Hypotension Treatment on Rehab Unit
Orthostatic Hypotension · Falls
Primary: Orthostatic Hypotension at Discharge — 39; 44 Participants — p=0.6