N/A N=249 Hyperopia Treatment Study 1 (HTS1) - Glasses vs Observation
Hyperopia
Primary: Number of Participants With Confirmation of Failure Criteria — 5; 4; 11; 18 Participants — p=0.72
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=35 Enhancement of Emmetropization in Highly Hyperopic Infants
Hyperopia
Primary: Central Cycloplegic Refractive Error With Retinoscopy — 1.6; 1.2; 2.8 Diopters
N/A N=69 Safety and Effectiveness of Wavefront-Guided LASIK Correction of Hyperopic Refractive Errors
Hyperopia
Primary: Number of Eyes With a Loss of >2 Lines for Best Spectacle Corrected Visual Acuity (BSCVA) — 2 eyes
N/A N=80 A Study to Evaluate the Safety and Effectiveness of the Technols 217z Zyoptix System for Hyperopia
Hyperopia · Astigmatism
Primary: Percentage of Eyes With Uncorrected Visual Acuity (UCVA) of 20/40 or Better at 12 Months and 24 Months — 147; 140 eyes
N/A N=58 Correction of Farsightedness in Children Study
Hyperopia · Farsightedness
Primary: Change in Kaufman Test of Educational Achievement (K-TEA) Reading Comprehension Score as Measured From Baseline to After 6 Weeks of Assigned Treatment (Hyperopic or…
N/A N=24 Extended Depth of Focus Contact Lenses for Presbyopia
Presbyopia
Primary: LogMAR Visual Acuity — -0.07 logMAR
N/A N=78 Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Hyperopic Population
Visual Acuity
Primary: Binocular Visual Acuity (logMAR) — -0.07; -0.05; -0.05; -0.04 logMAR
N/A N=30 Marketed Contact Lens Real World Through Focus Curve
Visual Acuity
Primary: Distance Binocular LogMAR Visual Acuity — -1.072; -0.904; 0.9017; 0.557 -10*LogMAR
Phase 4 N=218 Visual Function After Implantation of Bilateral AcrySof ReSTOR Aspheric +3
Cataract
Primary: Uncorrected Visual Acuity (UCVA) — 0.05; -0.07; 0.15; 0.20 logMAR
N/A N=33 Vivity IOL: Emmetropia Compared to Monovision.
Presbyopia
Primary: Binocular Uncorrected Near (40 cm) Visual Acuity — 0.21; 0.39 logMAR
N/A N=35 Evaluation of Vision After Vivity IOL Implantation With a Target of Slight Myopia in the Non-dominant Eye
Cataract
Primary: Binocular Near Visual Acuity — 0.14 logMAR
N/A N=84 Accommodative Relief for Uncomfortable Non-Presbyopes
Asthenopia
Primary: Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) Score — 14.3; 12.8; 19.0 scores on a scale — p=<0.001
N/A N=139 Evaluation of a Daily Disposable Silicone Hydrogel Multifocal Contact Lens in Myopes and Hyperopes
Visual Acuity
Primary: Binocular logMAR Visual Acuity — -0.098; -0.043; 0.0797 LogMAR
N/A N=70 Clinical Evaluation of a Reusable Multifocal Optical Design in a Presbyopic Population Phase 2
Visual Acuity
Primary: Vision Scores — 42.2; 55.3; 52.4; 41.8 units on a scale
N/A N=16 Multifocal Contact Lens Use in Previous Contact Lens Wearers With Near Vision Demands
Presbyopia
Primary: Overall Satisfaction With the Lenses — 82.5; 64.4 Units on a Scale
N/A N=108 Acceptance & Tolerance Study of Multifocal Contact Lenses by Functional Emmetropes
Vision Correction
Primary: Proportion of Successful Contact Lens Wearers — 0.71 Proportion of Subjects
Phase 2 N=75 A Study to Evaluate the Safety and Efficacy of EV06 Ophthalmic Solution in Improving Vision in Subjects With Presbyopia
Presbyopia
Primary: Ocular Comfort Assessment Following Instillation at Baseline and the Day Prior to Each Study Visit — 3.2; 3.3; 2.4; 2.2 units on a scale
Phase 4 N=132 Presbyopia-Correcting Intraocular Lenses (IOLs)
Cataract
Primary: Best Corrected Visual Acuity — -0.075; -0.080; -0.081; 0.227 logMAR
Phase 2 N=65 Safety and Efficacy of AGN-199201 and AGN-190584 in Patients With Presbyopia
Presbyopia
Primary: Percentage of Participants With at Least a 2 Line Improvement From Baseline in Uncorrected Near Visual Acuity (UNVA) in the Non-Dominant Eye — 46.7; 70.6; 56.3; 68.8…
N/A N=20 Visual Outcomes of Vivity in Patients With High Axial Length
Cataract
Primary: Binocular Uncorrected Distance Visual Acuity (logMAR) — -0.1 logMAR
Phase 3 N=182 Safety and Efficacy Study BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic or Pseudophakic Presbyopia
Presbyopia
Primary: Proportion of Subjects With >=15 Letter Gain Without >=5 Letter Loss in Near Visual Acuity — 49.4; 35.0; 22.7 Percentage of participants — p=<.001
Phase 2 N=42 Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome
Down Syndrome · Refractive Errors
Primary: Distance Visual Acuity — 0.41; 0.41; 0.40; 0.43 logMAR — p=0.92
N/A N=39 Performance of a Multifocal Contact Lens - Presbyopia Study
Presbyopia
Primary: The Total Grade of Conjunctival Hyperemia — 4.25; 3.72; 3.51; 3.42 units on a scale
N/A N=171 Evaluation of the Clinical Performance of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses
Visual Acuity
Primary: HLHC Binocular logMAR Visual Acuities — -0.088; -0.018; 0.087 logMAR
N/A N=9 Early Feasibility Study Using IOPCL MAG to Improve Near Vision in ARMD Subjects
Low Vision · Age Related Macular Degeneration
Primary: Tilt of the PCIOL and IOPCL MAG Complex — 9; 9 Eyes
N/A N=121 OPTI-FREE® PureMoist® for Presbyopic Contact Lens Wearers
Presbyopia
Primary: Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) Score at Day 30 — 13.4; 15.8 units on a scale — p==0.0030
N/A N=39 Multifocal Lens Design Evaluation
Refractive Error · Presbyopia
Primary: Mean Binocular HC/HI Visual Acuity at Near (40 cm) — 0.08; 0.06; 0.05; 0.05 logMAR
N/A N=109 Multifocal High ADD Contact Lens Proof of Concept Trial
Presbyopia
Primary: High Contrast Visual Acuity (HCVA) Near Monocular — 0.18; 0.32 logMAR
N/A N=20 Accommodative Behaviors in Multifocal Contact Lenses
Accommodation Disorder
Primary: Objective Accommodative Response (in Diopters) on the Grand Seiko Autorefractor at 2.5 Diopters (40 cm) — 1.20; 1.03 Diopters
N/A N=49 Clinical Evaluation of a Multifocal Contact Lens on Symptomatic Patients
Presbyopia
Primary: Subject Reported Overall Vision Quality Using (CLUE)TM Questionnaire — 41.0; 39.0 units on a scale