N/A N=63 Idiopathic Hypertensive Anal Canal: a Place of Internal Sphincterotomy
Hypertensive Anal Canal
Primary: Effect of Closed Lateral Sphincterotomy and Chemical Sphincterotomy on Hypertensive Anal Canal
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=300 War-Drill Model Guided Treatment of Hemorrhoids With Nimsai Herbal (NAJ)
Hemorrhoids · Hemorrhoidal Disease
Primary: Hemorrhoid Regression Rate — 117; 33 Participants — p=<0.001
Phase 3 N=465 Diltiazem Hydrochloride Cream for Anal Fissure
Chronic Anal Fissure
Primary: Change From Baseline in Average of Worst Anal Pain Associated With or Following Defaecation for Week 4 (for the 7 Treatment Days Immediately Preceding the Week 4 Visit)…
Early Phase 1 N=40 Anal Resting Pressure After Bidet, Compared to Sitz Bath
Anorectal Disorders
Primary: Anal Resting Pressure Change — 90.2; 71.3; 88.1; 69.6 mmHg
N/A N=10 A Safety and Tolerability of Circumferential Anal Canal Radiofrequency Ablation For Anal Intraepithelial Neoplasia
Anal Intraepithelial Neoplasia (AIN) · High-grade Squamous Intraepithelial Lesions (HSIL)
Primary: Related Adverse Events — 1; 1 number of participants
N/A N=20 Safety and Efficacy Study of HET Bipolar System for Treatment of Stage I and Stage II Hemorrhoids
Hemorrhoids, Internal
Primary: Number of Participants With Resolution of Symptoms — 18 participants
N/A N=31 Correlation of Anal Acoustic Reflectometry Parameters With Degree of Rectal Intussusception and Prolapse
Pelvic Floor Disorders
Primary: Opening Pressure — 56.35; 39.01; 23.42 cmH20
Phase 1 N=20 Gut Butyrate and Blood Pressure in African Americans
Hypertension
Primary: Mean Daytime Blood Pressure — 137.5; 132.9; 128.2 mmHg
Phase 3 N=248 A Study to Determine the Effect of Nitroglycerin Ointment 0.4% (Cellegesic) on the Pain Associated With Chronic Anal Fissures
Fissure in Ano · Pain
Primary: Change From Baseline in Pain Intensity at Days 14-18 — -40.4; -34.9 Units on a scale
N/A N=40 Evaluation of the Rectal Reflex Using Anal Acoustic Reflectometry
Pelvic Floor Dysfunction
Primary: Opening Pressure — 34.44; 15.41 cmH2O
N/A N=12 Proof of Concept: "Bottom's Up" Seat to Treat Constipation
Constipation Aggravated · Pelvic Floor; Incompetency
Primary: Adverse Events — 0 Participants
Phase 2 N=103 Evaluate Safety and Efficacy of 25 mg Hydrocortisone Acetate Suppositories in Treatment of Internal Hemorrhoids
Internal Hemorrhoids
Primary: Reduction in Swelling — 2.3; 2.0 scores on a scale — p=0.8918
N/A N=1 Treatment of Hemorrhagic Radiation Proctitis Using the Halo System
Pelvic Neoplasms
Primary: Number of Participants With Adverse Events — 0 partipants
Phase 2 N=74 Effects of Alpha-1 Antagonist, Stress and Relaxation on Anorectal Functions
Constipation
Primary: Weekly Rate of Spontaneous Bowel Movements at 4 Weeks — 1.6; 1.3; 1.6; 1.3 spontaneous bowel movements per week — p=0.78
Phase 4 N=13 Bowel Care and Cardiovascular Function After Spinal Cord Injury
Spinal Cord Injury
Primary: Blood Pressure Change During Bowel Care — 90.5; 80 mmHg
N/A N=50 Open Hemorrohoidectomy Vs Transanal Hemorrhoidal Desarterialization in Hemorrhoids Grade III: The Effect on Symptoms
Hemorrhoids Third Degree
Primary: Hemorrhoidal Disease Symptom Score — 1; 7 units on a scale
Phase 3 N=300 Controlling Anal Incontinence by Performing Anal Exercises With Biofeedback or Loperamide (CAPABLe)
Fecal Incontinence
Primary: Change From Baseline St. Mark's (Vaizey) Score — -5.5; -4.4; -4.5; -3.4 units on a scale — p=0.092
N/A N=49 Pudendal Nerve Block for Hemorrhoidectomy
Hemorrhoids · Postoperative Pain
Primary: Postoperative Pain on the Visual Analogue Scale (VAS) — 1.4; 3.1 units on a scale
N/A N=80 Video-assisted Anal Fistula Treatment Versus Seton in the Management of High Peri Anal Fistula
Post Operative Pain · Recurrence
Primary: Number of Participants With Recurrence of Disease or Fistula — 5; 10 Participants
Phase 2 N=44 A Placebo-Controlled Study of Clonidine for Fecal Incontinence.
Fecal Incontinence
Primary: Mean Fecal Incontinence and Constipation Assessment (FICA) Score — 8.1; 9.1; 6.5; 7.6 units on a scale
Phase 1 N=16 Does Single Dose Imipramine Affect the Opening Pressure of the Urethral and Anal Sphincter?
Urinary Incontinence, Stress · Fecal Incontinence
Primary: Urethral Opening Pressure (UOP) — 2.90411; -3.623431 cmH2O — p=0.07
N/A N=50 Post-Marketing Clinical Follow-Up Trial to Evaluate the Performance and Safety of PROCTOeze® PLUS
Haemorrhoidal Disease
Primary: Assessment of Performance by the Improvement in the Quality of Life Measured Through the Score on The Short Health Scale for Haemorrhoidal Disease (SHSHD) — 14.04; 7.80…
N/A N=32 Randomized Clinical Trial on Transanal Irrigation
Low Anterior Resection Syndrome
Primary: LARS Score — 21.3; 32.2 score on a scale
N/A N=408 The Safety of Proctofoam-HC in the Third Trimester of Pregnancy
Hemorrhoids · Pregnancy
Primary: Birth-weight — 3406.9; 3487.7 grams — p=0.17
N/A N=52 Stapled TransAnal Rectal Resection (STARR) With Contour® TranstarTM
Obstructed Defecation Syndrome · Rectocele · Intussusception
Primary: Quality of Life — 3.2; 3.7; 2.8; 3.3 units on a scale — p=0.1340
N/A N=36 Evaluation of the Fast Fill Technique for Anal Acoustic Reflectometry (AAR) in the Incontinent Anal Sphincter
Faecal Incontinence
Primary: Opening Pressure — 35.13; 37.5 cmH2O
N/A N=22 A Trial of Radiofrequency Ablation for Anal Intraepithelial Neoplasia Using the HALO Ablation System
HIV-negative Subjects With Intra-anal Intraepithelial Neoplasia Containing High-Grade Squamous Intraepithelial Lesions
Primary: Clearance of Anal HSIL (High Grade Squamous Intraepithelial Lesion (HSIL) — 19 participants w histological clearance
Phase 2 N=10 Effect of Intrathecal Clonidine in Hypertensive Subjects With Poorly Controlled Blood Pressure
Hypertension
Primary: Change in Blood Pressure After Intrathecal Injection of Clonidine. — 79; 37 mm Hg
Phase 3 N=204 Study to Evaluate Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy
Hemorrhoids
Primary: Area Under the Curve (AUC) of the Numeric Rating Scale at Rest (NRS-R) Pain Intensity Scores — 359; 396 Units on a scale*hours
N/A N=20 The Use of an "Anal-Tape" in Patients With Fecal Incontinence
Fecal Incontinence
Primary: Any Improvment in the Fecal Incontince Quality of Life Scale (FIQoLs) — 2.8; 3.3; 1.9; 2.5 score on a scale