30 closest matches · ranked by relevance
Impulse Control Disorder · Parkinson Disease
Primary: Percentage of Participants Assessed as Very Much Improved or Much Improved Based on the Clinical Global Impression-Improvement (CGI-I) Scale — 54.4; 33.1 percentage of…
Impulsivity · Compulsive Overeating · Obesity
Primary: Change in NIH Examiner Flanker Task Reaction Time — -0.03; -0.12 seconds
Obsessive Compulsive Disorder · Trichotillomania
Primary: Composite Score of Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) and National Institute of Mental Health (NIMH) — -.38; .46; -.89; -.52 z scores — p== 0.56
Attention Deficit Hyperactivity Disorder
Primary: Number of Participants That Tested High (6 or More Symptoms) for ADHD by Type Determined by Adult ADHD DSM IV-TR Checklist — 2; 5; 2 Participants
Impulsive Behavior
Primary: Stop Signal Task (SST) — 255; 215; 297 milliseconds
Attention Deficit Hyperactivity Disorder
Primary: Change From Baseline in Total Score of Barratt Impulsiveness Questionnaire v.11 (BIS-11) After Single Dose (at Day 1) — -0.8; -0.4 Score on a scale
Internet Gaming Disorder
Primary: Percentage of Participants Who Completed All 6 Sessions — 40.6 percentage of participants
Mild Traumatic Brain Injury
Primary: Blood Oxygen Level Dependent (BOLD) Brain Signal Measured Using Functional MRI. — 270; 111 voxels — p=<0.0001
Tourette Syndrome
Primary: Stop Signal Reaction Time (SSRT) — 249; 245 milliseconds — p=0.49
Gambling
Primary: Yale-Brown Obsessive Compulsive Scale for Pathological Gambling (PG-YBOCS) — 16.9; 18.6; 9.7; 12.9 units on a scale
Internet Gaming Disorder
Primary: Percentage of Participants Who Complete All 6 Sessions — 78.9 percentage of participants
Attention Deficit Hyperactivity Disorder
Primary: Area Under the Receiver Operating Characteristic (ROC) Curve- Groundskeeper Game — 0.78 Proportion of accurate ADHD Diagnoses
Schizophrenia With Impulsivity
Primary: Change From Baseline Brain Activation in the Ventrolateral Prefrontal Cortex (VLPFC) Based on Change From Baseline to Week 6 in fMRI Blood Oxygen-level Dependent (BOLD)…
ADHD
Primary: ADHD Symptoms — 71.2; 78.4; 47.4; 55.5 Percent of item endorsement — p=<0.025
Attention Deficit Hyperactivity Disorder (ADHD)
Primary: Efficacy and Safety of SPN-810 on the Frequency of Impulsive Aggression (IA) Measured by the Impulsive Aggression Diary — -48.16; -47.88; -58.56 percent change of IA…
Hoarding Disorder
Primary: Number of Patients Who Met and Exceeded Response Criteria of Attention Deficit Hyperactivity Disorder Symptom Scale — 4 participants
Gambling · Tobacco Use Disorder
Primary: Yale-Brown Obsessive Compulsive Scale Modified for Pathological Gambling Total Score — 23.5; 20.4 units on a scale
Intermittent Explosive Disorder · Childhood Aggression · Oppositional Defiant Disorder
Primary: Number of Participants That Were Responders — 0; 5 Participants
ADHD
Primary: The Effects of ADHD Medication Versus Placebo on Cotinine Levels — 180.7; 274.0 ng/ml — p=<0.05
OCD · Decision-Making · tDCS
Primary: Strength of Behaving Model-based (Goal-directed) — 0.09; 0.07; -0.08; 0.06 units on a scale
Compulsive Buying
Primary: Yale Brown Obsessive Compulsive Scale Modified for CB (CB-YBOCS) — 22 units on a scale
Obsessive-Compulsive Disorder · Generalized Anxiety Disorder · Major Depressive Disorder
Primary: Transdiagnostic Repetitive Negative Thinking (Measured by the Perseverative Thinking Questionnaire [PTQ]) Assessed in Phase I (Pilot Trial) and Group Differences…
Pathological Gambling
Primary: Statistically Significant (p<0.05) Decrease From Baseline in Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling — 13.9 YBOCS score
Self-Injurious Behavior · Self Harm · Self-injury
Primary: Social Processing (Cyberball) fMRI Task: fMRI Responses — -621.4739585; -519.1597701; -63.33972338; -396.4460666 beta-weight
Attention Deficit Hyperactivity Disorder (ADHD)
Primary: Efficacy and Safety of SPN-810 on the Frequency of Impulsive Aggression (IA) Measured by the Impulsive Aggression Diary — -54.12; -51.64 Percent Change of IA behaviors…
Obsessive-Compulsive Disorder
Primary: Yale Brown Obsessive Compulsive Scale — 19.14; 21.24 Scores on a scale — p=<0.05
Mood Disorder · Disruptive Behavior Disorders
Primary: Change in Affective Reactivity Index - Youth (ARI-Y) — -2.9; -0.8 score on a scale
Pathological Gambling
Primary: Subjective Reinforcement Self-report Scales — 4.8; 4.8; 9.5; 9.3 units on a scale
Opioid-use Disorder · Tobacco Use Disorder
Primary: Attentional Bias for Smoking Stimuli — 501.53; 406.70 milliseconds
Intermittent Explosive Disorder
Primary: Overt Aggression Scale-Modified for Outpatient Use (OAS-M) — 7.86; 15.73; 8.88 units on a scale — p=0.622