N/A N=20 A Novel Parent Education Program for Early Intervention
Preterm Infant · Full-term Infant
Primary: Alberta Infant Motor Scale - Change in Total Percentile Score — 10; 0 change in percentile rank — p=0.016
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=72 Evaluation of a Novel Intervention for Infants At Risk for Neurodevelopmental Disorders
Autism Spectrum Disorder · Neurodevelopmental Disorders
Primary: Change in Mean Percent of Parent Child Dyadic Engagement Over Time From Baseline to Posttest 1 — 22.01; 16.91; 26.55; 27.09 percent time in dyadic engagement — p=0.028
N/A N=64 A Family Centered Intervention to Promote Optimal Child Development
Developmental Delays
Primary: Difference in the Number of Participants Who Completed Early Intervention Intake and Evaluation Visits Between Treatment Groups — 20; 21; 17; 17 participants
N/A N=12 Movement-based Infant Intervention
Infant Development · Infant,Premature · Infant, Very Low Birth Weight
Primary: Movement Rate — 1278 average leg movements per hour awake
N/A N=36 SmarToyGym: Smart Detection of Atypical Toy-oriented Actions in At-risk Infants
Cerebral Palsy · Developmental Delay · Stroke
Primary: Center of Pressure, Path Length Per Second - No Toy (Birth Status) — 0.0282; 0.0428 centimeters per second (cm/sec) — p=0.0054
N/A N=26 Effectiveness of Telerehabilitation in High Risk of Infants
Early Intervention
Primary: Bayley III - Cognitive — 77.69; 78.46 score on a scale
N/A N=198 Feeding and Transition to Home for Preterms at Social Risk
Premature Birth
Primary: Infant Behavioral Organization — 33.2; 51.8 Orally directed behavioral cues per week
N/A N=7 Resident Surveillance of Pediatric Patient Developmental Status at the Two Month Preventive Care Visit
Growth & Development · Child Development · Internship and Residency
Primary: Presence of Resident Surveillance Behaviors of Specific Aspects of Developmental Status at the Two Month Preventive Care Visit — 3 Participants
N/A N=30 Movement Enhancing Device for Children
Upper Extremity Dysfunction
Primary: Change in Time Contacting Objects — 40.75 percentage of time — p=<.05
N/A N=134 Efficacy of the START-Play Program for Infants With Neuromotor Disorders
Cerebral Palsy · Developmental Delay · Infant Development
Primary: Bayley Scales of Infant Development III — 35.9; 33.6; 31.7; 29.4 score on a scale — p=<0.05
N/A N=56 Evaluation of an Interdisciplinary Decision Guide for Infant Feeding Assessment
Premature Birth · Feeding and Eating Disorders of Childhood
Primary: Number of Participants That Recommend Feeding Therapy — 27; 27; 1; 1 Participants
N/A N=70 NEO Rehab Program for Premature Infants at Risk for Cerebral Palsy
Cerebral Palsy · Prematurity · Early Intervention
Primary: Acceptability — 70 Participants
N/A N=97 Working on Rapid Language Development in Toddlers
Language Developmental Disorders
Primary: Language Skills at 4 Months After Baseline as Measured by the Pre-school Language Scale - 4th Edition — 84; 80.2 units on a scale
N/A N=63 Prospective Research in Infants With Mild Encephalopathy
Hypoxic-Ischemic Encephalopathy · Brain Injury · Neonatal Seizure
Primary: Percentage of Infants With Evidence of Neurological Dysfunction, Brain Injury and/or Abnormality. — 28 Participants
Phase 2 N=256 Effects of Delayed Cord Clamp and/or Indomethacin on Preterm Infant Brain Injury
Intraventricular Hemorrhage · Periventricular Leukomalacia · Brain Injury
Primary: Percent of Survivors With no Severe IVH (Grades 3 or 4) or PVL — 22.2; 14.9; 17.1; 10.9 percent of participants
N/A N=19 Translating Peer-to-Peer Support Into a Clinical Setting
Development Delay · Neurodevelopmental Disorders · Autism
Primary: Parenting Stress — 14.4; 12.2 score on a scale
N/A N=360 The CHICA Developmental Screening Study
Developmental Delay
Primary: Number of Children Screened for Developmental Delay — 153; 44 Participants
N/A N=152 Testing the Effectiveness of Telephone-based Early Childhood Developmental Screening
Child Development · Developmental Disabilities · Ambulatory Care
Primary: Number of Participants Screened With a Validated Tool — 57; 0 Participants
N/A N=17 Use of Partial Body Weight Support Play Environment to Encourage Mobility and Exploration in Infants With Down Syndrome
Down Syndrome · Trisomy 21
Primary: Change in Movement Counts Per 15 Seconds From Baseline (Week 1) to Mid Study (Week 5) — -34.46; -88.62 movement counts per 15 seconds
N/A N=248 Trial to Improve Multisensory Neural Processing, Language & Motor Outcomes in Preterm Infants
Preterm Infant
Primary: Index of Multisensory Processing (IMP) — 31.4; 49.0; 35.6; 18.8 percentage of time
Phase 3 N=144 Effect of Early L-Carnitine Supplementation on Neurodevelopmental Outcomes in Very Preterm Infants
Prematurity · Neurodevelopmental Disorder · Carnitine Deficiency
Primary: Time to Regain Birthweight in Infants Who Receive L-carnitine Supplementation Compared to Controls — 8.12; 8.4 days — p=<0.05
N/A N=81 Screening for Autism Spectrum Disorders Using Auditory Brainstem Responses
Autism Spectrum Disorder
Primary: ABR Peak V Latency — 6; 5.8; 6.29; 5.99 ms
N/A N=28 Pattern - Reach Aim 2
Obesity
Primary: Number of Participants Satisfied or Very Satisfied With Information Given to Them, as Measured by Follow up Questionnaire — 4; 2 Participants
N/A N=11 Therapeutic Intervention Supporting Development From NICU to 6 Months for Infants Post Hypoxic-Ischemic Encephalopathy
Cerebral Palsy · Hypoxic-Ischemic Encephalopathy
Primary: Feasibility of the Neonatal Intensive Care Unit Component of the Intervention. — 0; 1 Participants
Phase 2 N=100 Brief Intervention in At-Risk First-time Mothers
Substance Use
Primary: Alcohol Use — 1.37; 0.92 units on a scale
N/A N=127 Iron Treatment for Young Children With Non-anemic Iron Deficiency
Non-anemic Iron Deficiency
Primary: Early Learning Composite (ELC) From the Mullen Scales of Early Learning — 113.0; 113.5; 110.48; 107.94 units on a scale
Phase 2 N=28 Mild Encephalopathy in the Newborn Treated With Darbepoetin
Neonatal Encephalopathy · Hypoxic-Ischemic Encephalopathy Mild
Primary: Normal Neurodevelopment — 13; 14 Participants
N/A N=10 Using the LENA System in Early Intervention - b
Depression
Primary: LENA Adult Word Count Score at 6 Weeks — 18391.25 number of words
N/A N=14 Initial Efficacy Study of Supporting Play, Exploration, & Early Development Intervention
Infant, Premature, Diseases · Brain White Matter Disease Periventricular
Primary: Reaching (Toy Contact Duration) — 20.2; 28.02 Seconds
N/A N=959 The Pro-Parenting Study: Helping Parents Reduce Behavior Problems in Preschool Children With Developmental Delay
Development Delay · Behavior Problem
Primary: Change From Baseline in Child Behavior Problems (Parent Report) — 73.60; 77.95; 71.49; 71.69 score on a scale — p=.361