N/A N=159 Decreasing Delirium Through Music in Critically Ill Older Adults
Intensive Care Unit Delirium · Pain · Anxiety
Primary: Days Free of Delirium and Coma — 2.5; 3 Delirium/coma-free days by day 7 — p=0.775
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=551 Pharmacological Management of Delirium
Delirium · Cognitive Impairment
Primary: Days Free of Delirium and Coma — 4; 5; 4; 5 days
N/A N=219 Nursing Assistant Intervention to Prevent Delirium in Nursing Homes
Delirium
Primary: Number of Participants With Delirium — 41; 33 Participants
Phase 2 N=53 Randomized Controlled Trial of Dexmedetomidine for the Treatment of Intensive Care Unit (ICU) Delirium
Delirium · Agitation
Primary: Resolution of Delirium — 21; 14 Participants
N/A N=283 Early Cognitive Intervention in Delirium
Delirium · Cognitive Decline · Dementia
Primary: Global Cognition as Measured by the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) — 67; 67 score on a scale
Phase 3 N=100 The Effect of Guanfacine on Delirium in Critically Ill Patients
Delirium
Primary: Days Without Delirium — 2.54; 3.38 delirium free days — p=0.22
N/A N=498 Delirium in the Emergency Department: Novel Screening
Delirium
Primary: Delirium — 98.0; 56.2; 56.2; 54.8 percent
N/A N=100 Effects of Scenario-based Education Initiative and OSCE for Recognition and Management of Delirium
Delirium
Primary: Delirium Knowledge — 12.40; 13.26; 13.08; 12.71 point
N/A N=234 A Study to Evaluate ICU Simulation Experience in the Cardiothoracic Surgical Population to Reduce Post-operative Delirium
Post-Operative Delirium
Primary: Confusion Assessment Method for the ICU (CAM-ICU) — 4; 1 Participants
Phase 3 N=168 Effects of Dexmedetomidine on Delirium Duration of Non-intubated ICU Patients (4D Trial)
Delirium · Agitation
Primary: Duration of Agitation (in Hours), Defined by a RASS ≥ +1 — 1; 2 hours
N/A N=178 Family Automated Voice Reorientation Study
Delirium · Cognitive Impairment · Health, Subjective
Primary: Delirium-free Days — 8.4; 7.2 days
Phase 3 N=566 The Modifying the Impact of ICU-Associated Neurological Dysfunction-USA (MIND-USA) Study
Delirium · Impaired Cognition · Long Term Psychologic Disorders
Primary: Delirium/Coma-free Days (DCFDs) — 8; 8; 7 days
N/A N=232 Vanderbilt ICU Recovery Program Pilot Trial
Intensive Care Unit Syndrome · Intensive Care Neurological Disorder · Intensive Care (ICU) Myopathy
Primary: Number of Components of the ICU Recovery Program Received — 2; 1 interventions
Phase 3 N=672 The Prevention of Delirium and Complications Associated With Surgical Treatments Multi Center Clinical Trial
Delirium
Primary: Number of Patients With Incidence of Delirium Across All Patients at Baseline and Over Post-operative Days 1-3 — 85; 43 Participants — p=0.912
N/A N=91 Postoperative Delirium: Brain Vulnerability and Recovery
Delirium · Postoperative Complications
Primary: EEG During Delirium and After Recovery and in Patient Controls.
N/A N=49 Feasibility and Acceptability of Using Weighted Blankets to Prevent and /or Mitigate Delirium
Delirium
Primary: Study Participants Experience Survey — 3.61 Scores on a likert scale (1-5)
Phase 3 N=469 Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep
Postoperative Delirium · Sleep · Anesthesia
Primary: Incidence of Delirium — 5; 16 Participants — p=0.029
Phase 4 N=60 Dexmedetomidine Versus Morphine and Midazolam in Prevention and Treatment of Delirium After Adult Cardiac Surgery
Delirium
Primary: The Incidence of Delirium (Number of Patients (in Digits)) — 1; 2 participants
N/A N=1,609 24 Hour Intensivist Coverage in the Medical Intensive Care Unit
Critically Ill
Primary: MICU Length of Stay — 52.8; 52.6 hours
N/A N=9 Neurosciences-Intensive Care Unit Electrical Stimulation
Intensive Care (ICU) Myopathy
Primary: Duration of Intubation — 10.22 days
N/A N=16 Feasibility Pilot of Bright Light in the Intensive Care Unit
Circadian Rhythm Sleep Disorder, Unspecified
Primary: Tolerance (Time): Percent of Intended Treatment Hours That Patient Continues With the Delivery of Bright Light — 59; 61 percentage of intended treatment hours
Phase 4 N=135 Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy
Delirium · Cognitive Impairment · Post-traumatic Stress Disorder
Primary: Efficacy of Low-dose Haloperidol in Reducing Delirium Incidence — 15; 19 Participants
N/A N=81 Delirium Treatment With Acupuncture in Internal Medicine Departments
Delirium in Old Age
Primary: Number of Delirium-free Days During the 7 Days of Evaluation — 5.5; 0 days — p=<0.001
Phase 4 N=100 Suvorexant and Sleep/Delirium in ICU Patients
Insomnia · Sleep Fragmentation · Sleep Initiation and Maintenance Disorders
Primary: Nighttime Wakefulness After Persistent Sleep Onset (WASO) — 200.7; 184.2 minutes
N/A N=80 Mobile Mindfulness to Improve Psychological Distress After Critical Illness
Psychological Distress · Depression · Anxiety
Primary: Percent of Eligible Participants Who Provided Consent — 90 Participants
N/A N=737 Determining the Preliminary Efficacy of the Emergency Department Delirium Screening and Detection Program
Delirium
Primary: Proportion of Positive Delirium Screens Among Those With Delirium — 0; 10; 0; 1 Participants
N/A N=18 Implementation Outcome Assessments of the Emergency Department Delirium Screening and Detection Program
Delirium
Primary: Accurate Delirium Screening by Emergency Department (ED) Nurses (RE-AIM: Efficacy) — 4; 1; 8 Site nurses who received Spot Check Form
Phase 4 N=285 Dexmedetomidine and Delirium in Patients After Cardiac Surgery
Delirium · C.Surgical Procedure; Cardiac · Postoperative Complications
Primary: Incidence of Postoperative Delirium — 7; 11 Participants — p=0.341
N/A N=252 Impact on Mental, Physical, And Cognitive Functioning of a Critical Care sTay During the COVID-19 Pandemic
Covid19 · Critical Care · Postintensive Care Syndrome
Primary: World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) — 5; 13.5 units on a scale
N/A N=153 Improving the Recovery and Outcome Every Day After the ICU
Delirium · Alzheimer Disease
Primary: Cognitive Status Outcome at 6 Months — 0.24; 0.36; 0.21; 0.35 Z-score — p=0.747