Clinical Trial Search

Primary: Number of Responders Based on the Average Investigator Evaluation of Change From Baseline for All Treated Areas on the Global Ordinal Rating Scale (GORS) — 10 participants

Primary: Peri-Implant Mucosal Zenith Distance (in Millimeters) at the Concave/Divergent Abutment Sites — 9.860; 9.770; 9.684; 9.618 millimeters

Primary: Vertical Recession — 3.35; 3.20; 0.38; 0.65 mm — p=0.259

Primary: Percentage of Subjects With at Least 2 mm Keratinized Tissue (KT) at 6 Months at the Gintuit Treated Site. — 95.3 percentage of participants — p=<0.0001

Primary: Changes in Soft Tissues Around Implant — 243.89 root mean square in µm

Primary: Gingival Thickness — 1.97; 1.95; 1.39 millimeter

Primary: Recession Height — 1.0; 0.9 mm

Primary: Gingival Index (GI) — 1.04; 1.01 units on a scale — p=<0.05

Primary: Change in Absent in Melanoma 2 (AIM2) mRNA Expression Levels — 0.37; 0.65 fold change — p=0.3

Primary: Bleeding on Probing (BOP) — 14.5; 12.3 percentage of sites

Primary: Change in Interproximal Plaque by Modification of the Quigley-Hein Plaque Index at 14 Days — 0.03; -0.07 score on a scale

Primary: Recession Depth — 2; 2; 0; 0 length in millimeters

Primary: Percentage of Defect Coverage — 15; 14 Gingival recessions

Primary: Serum Concentrations of Interleukin (IL)-1 Beta — 1100.00; 896.21; 65559; 45734 pg/ml

Primary: Change From Baseline Gingivitis at Day 14 as Measured by Non-invasive Microimaging and Gingival Index. — 0.6; 0.15 units on a scale

Primary: Change in Total Bacterial Load on the Exposed Implant Surface — 2.77; 4.21 log (colony forming units/ml)

Primary: Change in Clinical Attachment Level (CAL) — 1.21; 1.03 mm

Primary: Pink Esthetic Score (PES) at Temporary Crown Delivery. — 1; 1; 1; 1 score on a scale — p=0.0007

Primary: Change From Baseline in Patient Comfort for as Assessed by Numerical Scale. — 0.99; 1.16 units on a scale

Primary: Mean Probing Pocket Depth — 4.62; 4.45 millimeters

Primary: Periodontal Pocket Depth-PPD — 3.735; 3.696 mm — p=0.429

Primary: Clinical Attachment Level — 6.42; 6.15; 3.52; 3.6 mm

Primary: Mombelli Plaque Index (mPI) for Natural Teeth — 1.96; 1.82 units on a scale — p=0.05

Primary: Clinical Outcome Based on Success After Intervention on MIH Affected Molar at 6 Months — 17; 18; 17 number of Successful MIH affected molars

Primary: Gingival Recession at Sites With Preexisting Recessions ≥2mm — 2.09; 2.08 mm

Primary: Percentage of Participants With Tooth Loss Over 16 Year Period — 16.4; 13.8; 22.1; 16.9 percentage of participants

Primary: Vitality of Teeth (Units) Using Thermal and Percussion Sensitivity Trend Observed During Study Duration (3-11 Months) — .559; .592; .065; .040 Teeth

Primary: Mean Mid-facial Recession Coverage (mRC) — 60.7; 91.8 percentage

Primary: Percentage of Root Coverage — 66; 73 percentage of area covered

Primary: Change in Buccal Peri-implant Mucosa Thickness Between Baseline and 16 Weeks After Surgery — 0.44; 0.05 millimeters