Phase 2 N=97 Low-dose Atropine for the Prevention of Myopia Progression in Danish Children
Myopia
Primary: Axial Length at 36 Months — 25.28; 25.25; 25.33 mm
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=86 Bifocal Soft Contact Lenses and Their Effect on Myopia Progression in Children and Adolescents.
Myopia · Esophoria · Fixation Disparity
Primary: Changes in Cycloplegic Autorefraction in One Year. — -0.22; -0.78 Diopters
N/A N=100 Myopia Assessment of Two Manufacturing Processes
Juvenile Myopia
Primary: Change in Axial Length Progression From Baseline — 0.046; 0.047 mm
N/A N=45 Effectiveness of Orthokeratology in Myopia Control
Myopia
Primary: Axial Length — 25.32; 26.08 mm
N/A N=53 Investigation of Wearing Compliance of Spectacles for Myopia Control
Myopia
Primary: Overall Wearing Pattern of Myopia Control Spectacles — 12.8 Hours in a day
N/A N=49 Bifocal & Atropine in Myopia (BAM) Study
Refractive Errors
Primary: Refractive Error Progression — -3.50 Diopter — p=0.70
Phase 3 N=118 Correction of Myopia Evaluation Trial 2
Myopia
Primary: Distribution of Change in Spherical Equivalent Refractive Error From Baseline to 3 Years — 6; 3; 11; 8 participants
N/A N=71 Topical Application of Low-concentration (0.01%) Atropine on the Human Eye With Fast and Slow Myopia Progression Rate
Myopia
Primary: Annualized Changes in Refractive Error (SER) — -0.70; -0.66 Dioptre/year
N/A N=144 An Evaluation of the Effectiveness of Dual Focus Soft Contact Lenses in Slowing Mypoia Progression
Myopia
Primary: Change in Refractive Error Relative to Baseline — -0.18; -0.58 Diopters
Phase 3 N=187 Low-Dose Atropine for Treatment of Myopia
Myopia
Primary: Treatment Group Comparison of Change in Spherical Equivalent Refractive Error. — 0; 0; 1; 0 Participants
N/A N=152 Controlling Myopia Progression With Soft Contact Lenses
Myopia
Primary: Axial Length (Axial Elongation) — 0.158; 0.144; 0.121; 0.242 millimeter (mm)
N/A N=137 Controlling Myopia Progression With Soft Contact Lenses
Myopia
Primary: Spherical Equivalent Refraction — -0.326; -0.460; -0.430; -0.898 diopter (D)
N/A N=294 Bifocal Lenses In Nearsighted Kids
Refractive Errors
Primary: Refractive Error Progression — -3.46; -3.32; -2.84 Diopters — p=<0.01
N/A N=102 Retardation of Myopia in Orthokeratology
Myopia
Primary: Axial Elongation in the Study and Control Subjects Who Completed the Two Years Study — 0.36; 0.63 mm
N/A N=35 Enhancement of Emmetropization in Highly Hyperopic Infants
Hyperopia
Primary: Central Cycloplegic Refractive Error With Retinoscopy — 1.6; 1.2; 2.8 Diopters
N/A N=127 Controlling Myopia Progression With Soft Contact Lenses (Contact Lens Control)
Myopia
Primary: Spherical Equivalent Refractive Error — -0.386; -0.185; -0.679; -0.548 diopter (D)
Phase 3 N=576 CHAMP: Study of NVK-002 in Children With Myopia
Myopia
Primary: Number of Subjects' Eyes That Show < 0.50 D Myopia Progression (SER, Spherical Equivalent Refraction) at the Month 36 Visit — 79; 106; 61 participants' eyes
N/A N=92 Evaluation of the Efficacy in Decreasing Myopia Progression of the Proposed Ophthalmic Lens Prototypes
Myopia
Primary: Axial Lenght Increase — 0.27; 0.37 mm
N/A N=183 Myopia Control With the Multi-segment Lens
Myopia
Primary: Cycloplegic Refraction Change in SER — -0.93; -0.38 Diopters (D)
N/A N=248 Examination of Myopia Progression and Soft Bifocal Contact Lens Myopia Control
Myopia
Primary: The Statistical Correlation Between Three-year Change in Choroidal Thickness and Three-year Change in Axial Length — 0.18 mm axial length — p=<0.001
N/A N=146 Observational Study of Optical Correction for Strabismic Amblyopia in Children 3 to <7 Years Old
Amblyopia
Primary: Mean Amblyopic Eye Visual Acuity Improvement With Spectacles — 2.3; 3.2 logMAR units
N/A N=249 Hyperopia Treatment Study 1 (HTS1) - Glasses vs Observation
Hyperopia
Primary: Number of Participants With Confirmation of Failure Criteria — 5; 4; 11; 18 Participants — p=0.72
N/A N=100 Evaluation of a Night Spectacle Correction Concerning an Improvement of Mesopic Vision Quality
Myopia-Night Blindness
Primary: Night Myopia — -0.30; -0.32 D
N/A N=31 The Safety and Effectiveness of Breath-O Lenses
Myopia · Safety Issues
Primary: Corneal Biomechanics in Terms of Corneal Hysteresis and Resistance Factor — 11.12; 11.10; 10.37; 11.20 mmHg
N/A N=82 Myopia Progression After Ceasing Myopia Control Contact Lens Wear
Myopia
Primary: Axial Length of the Eye — 0.080; 0.073; 0.229; 0.231 millimeter (mm)
N/A N=53 Discontinuation of Orthokeratology on Eyeball Elongation in Myopic Children
Myopia
Primary: Change in Axial Length — 0.153; 0.087; 0.082; 0.059 mm
N/A N=58 A Pilot Clinical Trial of Overminus Spectacle Therapy for Intermittent Exotropia
Intermittent Exotropia
Primary: Mean Distance Exotropia Control Score — 2.0; 2.8 points on control score scale — p=0.01
N/A N=75 Visual Performance of Soft Contact Lenses With Myopia Control Optics
Visual Acuity
Primary: Binocular Visual Performance (LogMAR) — -0.10; -0.10; -0.07; -0.11 logMAR
N/A N=21 Evaluation of The Clinical Acceptance of Soft Contact Lenses for Myopia Control
Myopia
Primary: Overall Vision Satisfaction — 87.7; 79.7; 71.8 units on a scale
N/A N=114 VisuMax Femtosecond Laser Small Incision Lenticule Extraction for the Correction of High Myopia
Myopia · Refractive Errors
Primary: Variability of the Refractive Predicatibility — -0.22 Diopters