N/A N=23 Skeletal Muscle Atrophy and Dysfunction Following Total Knee Arthroplasty
Knee Osteoarthristis
Primary: Cross-sectional Area (CSA) of Muscle Fibers — 2680; 2377; 2028; 1882 micron squared
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=179 Persistent Postoperative Pain and Joint Stiffness After Total Knee Arthroplasty Performed for Osteoarthritis
Pain · Joint Stiffness
Primary: Presence of Persistent Postoperative Pain Using the Numeric Rating Scale (NRS) — 10 Participants
N/A N=26 Transcutaneous Electrical Nerve Stimulation After Total Knee Arthroplasty.
Transcutaneous Electric Nerve Stimulation · Pain
Primary: Change in Pain Level From Baseline to 90 Minutes — 3.1; 3.3 Units on a scale
N/A N=120 Postoperatory Analgesia After Total Knee Arthroplasty
PAIN
Primary: Postoperatory Analgesia After Total Knee Arthroplasty Comparing Femoral and Sciatic-femoral Block — 2; 2.8; 1.5 units on a scale
N/A N=76 Home Rehabilitation in Patients After Primary Total Knee Arthroplasty
Osteoarthritis · Rehabilitation
Primary: Total WOMAC Score — 51.64285714; 52.47619048; 39.60714286; 40.38095238 score on a scale
Phase 4 N=160 Management of Postoperative Pain After Total Knee Replacement.
Postoperative Pain · Knee Replacement Arthroplasty
Primary: Post-Operative Pain — 2.9; 3.0 units on a scale — p=0.76
Phase 2 N=120 Effects of Pregabalin on Pain After Total Knee Arthroplasty
Primary Total Knee Arthroplasty
Primary: Postoperative Pain — 4; 4.8; 4.5; 4.0 units on a scale
N/A N=48 Total Knee Arthroplasty: Functional and Clinical Outcomes
Knee Osteoarthritis
Primary: Change in Lower Quarter Y-Balance Test (YBT-LQ) (Dynamic Balance) From Baseline to 6 Weeks Following Total Knee Replacement — 69.98; 67.52; 73.25; 73.32 % of limb length…
Phase 4 N=40 Genicular Nerve Block for Total Knee Arthroplasty
Post-operative Pain
Primary: Opioid Consumption at 24 Hours Post-op — 22.9; 58.1 milligrams of oral morphine equivalents
N/A N=311 Risk Factors and Mechanisms for Persistent Postsurgical Pain After Total Knee Replacement
Persistent Postsurgical Pain
Primary: Number of Subjects With Post-Operative Persistent Pain (PPP) — 211; 34 Participants
Phase 4 N=99 Efficacy of Ipack Block and Surgeon's Joint Infiltration in Total Knee Arthroplasty
Osteo Arthritis Knee
Primary: Narcotic Consumption — 15.87; 13.67 morphine equivalents, mg
N/A N=165 Tourniquet on Total Knee Arthroplasty
Arthritis Knee
Primary: Pain After TKA Measured by VAS Pain Survey on Focusmotion App — 2.8; 2.6 score on a scale
N/A N=116 Evaluation of Electrical Nerve Stimulation (TENS) Therapy for Pain Relief Following Total Knee Arthroplasty (TKA)
Osteoarthritis, Knee · Arthritis · Pain
Primary: Narcotic Usage — 997.7; 1025.8 morphine equivalents
Phase 4 N=5 Open-label Milnacipran for Persistent Knee Pain One Year After Total Knee Arthroplasty (TKA)
Knee Pain After Total Knee Arthroplasty · Osteoarthritis Pain
Primary: Change in Pain Visual Analogue Scale(VAS). — 44 units on a scale
N/A N=60 Adductor Canal Block for Total Knee Arthroplasty
Arthroplasty, Replacement, Knee · Pain, Postoperative
Primary: 10 Meter Walk Test — 38.6; 49.8; 43.3 Seconds
N/A N=10 Home Monitoring After Primary Total Knee Arthroplasty
Osteoarthritis, Knee
Primary: Overall Reliability of Monitoring Technology, Measured as Proportion of Actual Data Received From the Patient's Home Compared to the Amount of Data Expected (Based on…
N/A N=60 Manual Lymphatic Drainage Following Total Knee Arthroplasty Surgery
Knee Arthroplasty, Total
Primary: Bioimpedance Percentage Difference Healthy/Operated — 1.8; 0.2; 12.9; 13.7 percentage difference between limbs — p=0.51
N/A N=26 Improving Function After Knee Arthroplasty With Weight-Bearing Biofeedback
Arthropathy of Knee Joint
Primary: Weight-bearing Ratio During Five Times Sit-to-Stand Test (FTSST) — 0.77; 0.8 ratio — p==0.329
N/A N=36 Defining Normal Postoperative Magnetic Resonance Imaging After Total Knee Arthroplasty
Local Anesthetic Complication · Local Anesthetic Drug Adverse Reaction
Primary: Number of Participants With Edema — 12 participants
N/A N=240 Comparison of Treatments Following Total Knee Replacement
Degeneration; Articular Cartilage, Knee · Rheumatoid Arthritis · Osteoarthritis, Knee
Primary: The Western Ontario and McMaster Universities Osteoarthritis Index Physical Function (WOMAC-PF). — 20.9; 20.4; 20.2; 10.1 units on a scale — p=0.071
N/A N=60 Postoperative Knee Strength Following Total Knee Replacement: A Double-Blinded Randomized Comparison Study
Total Knee Replacement · Primary Knee Arthroplasty
Primary: Comparison of Postoperative Strength (Extension) — .08; .03; .05 Nm/kg
Phase 4 N=38 Patellar Resurfacing Versus Patellar Retention in Total Knee Arthroplasty - A Randomized Clinical Trial
Total Knee Replacement
Primary: Change in Western Ontario MacMaster (WOMAC) Osteoarthritis Index Pain Score From Preoperative to 5 Years Postoperative — 34.7; 39.2 units on a scale — p=0.59
N/A N=50 Knee Kinematics for Subjects With Zimmer-Biomet Posterior Cruciate Retaining or Posterior Stabilizing Total Knee Arthroplasty
Arthroplasty, Replacement, Knee · Osteoarthritis, Knee
Primary: Lateral Condyle Kinematic Translations - Step up — 1.15; 2.28 mm
N/A N=1,250 Evaluation of Patellar Crepitus Following Total Knee Arthroplasty
Total Knee Replacement
Primary: Evaluate for the Incidence of Patellar Crepitus Requiring Non-operative vs. Operative Treatment of Both the Study and Control Groups at a Minimum of 12 Months Following…
N/A N=40 Early Postoperative Compex Rehab NMES Use for Total Knee Arthroplasty Patients
Knee Osteoarthritis
Primary: Change in Quadriceps Force — 49.0; 28.4 Newtons (N)
N/A N=455 Safety of Total Knee Replacement Surgery Before and After the Implementation of Enhanced Recovery Program
Arthroplasty Complications
Primary: Number of Patients With Early Complication — 9; 16; 4 Participants
Phase 2 N=44 Effectiveness of Minimally Invasive Total Knee Replacement in Improving Rehabilitation and Function
Osteoarthritis
Primary: Quadriceps Muscle Force — 1.27; 1.37; 0.79; 0.66 Nm/kg — p=0.07
N/A N=92 Optimizing Physical Activity Outcomes After Total Knee Arthroplasty
Total Knee Arthroplasty · Osteoarthritis
Primary: Free-living Daily Step Count — 6947; 6339 step count — p=0.024
Phase 2 N=54 Safety and Efficacy of Botulinum Toxin A Injection in Patients With Painful Artificial Knee Arthroplasty (TKA)
Knee Pain
Primary: Participants With Clinically Meaningful Improvement in Pain Severity (0-10 cm; Higher Score on Pain Scale is Worse) — 15; 9 participants
Phase 4 N=111 The Combination of Adductor Canal Block and Periarticular Injection. A Novel Technique for Patients Undergoing Total Knee Replacement (ACB PAI)
Osteoarthritis
Primary: Time to Meet Physical Therapy Discharge Criteria — 2109.3; 1883.1 Minutes