Phase 4 N=114 Dronabinol in Total Knee Arthroplasty (TKA)
Total Knee Arthroplasty · Opioid Use
Primary: Cumulative Opioid Consumption 24-48 Hours Post-operatively — 8; 15 morphine milligram equivalents — p=0.27
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=60 Effect of Low Dose Corticosteroids on Perioperative Markers of Thrombosis and Fibrinolysis in Total Knee Arthroplasty
Total Knee Arthroplasty
Primary: Prothrombin Fragment (PF1.2), a Marker of Thrombin Generation — 263.6; 266.5; 935.8; 615.9 pMol/L
N/A N=71 Molecular Pathways Involved in Knee Pain
Knee Osteoarthritis · Knee Pain Chronic
Primary: Pain Sensitivity: Pressure Pain Detection Threshold (PPT) — 252.58; 266.17 kPa
Phase 2 N=11 Trigger Point Injection in Reducing Pain Following Total Knee Arthroplasty
Trigger Point Pain, Myofascial
Primary: Pain Scores on the Visual Analog Scale — 51; 55; 40; 42 Pain Scores on the Visual Analog Scale
Phase 3 N=3,307 A Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Naproxen for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip
Osteoarthritis, Knee · Osteoarthritis, Hip
Primary: Change in the WOMAC Pain Subscale Scores From Baseline to Week 16 in Participants Treated With Fasinumab 1mg SC Q4W Compared With That of Participants Treated With…
N/A N=70 Does Radiofrequency Ablation of the Articular Nerves of the Knee Prior to Total Knee Replacement Improve Pain Outcomes
Arthroplasty, Replacement, Knee
Primary: Opioid Consumption After Surgery — 192; 144 Morphine Equivalents (ME) — p=.978
N/A N=140 Opioid Consumption and Disposal After Shoulder Arthroplasty
Opioid Use
Primary: Difference in Proportion of Participants With > 10 Pills Left Unused. — 49; 47 Participants
Phase 2 N=54 Safety and Efficacy of Botulinum Toxin A Injection in Patients With Painful Artificial Knee Arthroplasty (TKA)
Knee Pain
Primary: Participants With Clinically Meaningful Improvement in Pain Severity (0-10 cm; Higher Score on Pain Scale is Worse) — 15; 9 participants
N/A N=240 Comparison of A Mobile-Bearing Total Knee System With A Fixed-Bearing Total Knee System In Cemented Total Knee Arthroplasty
Degenerative Joint Disease
Primary: Maximum Knee Flexion — 110; 111; 111; 109.0 degrees — p=0.64
Phase 4 N=80 Femoral Versus Adductor Canal Continuous Peripheral Nerve Blocks for Knee Arthroplasty
Postoperative Pain Following Knee Arthroplasty
Primary: Hours Until Discharge Readiness — 61; 55 hours
Phase 2 N=120 Effects of Pregabalin on Pain After Total Knee Arthroplasty
Primary Total Knee Arthroplasty
Primary: Postoperative Pain — 4; 4.8; 4.5; 4.0 units on a scale
N/A N=100 Ketamine Administration for Postoperative Pain Management in Patients Undergoing Knee Arthroplasty
Knee Arthroplasty · Postoperative Pain · Pain Management
Primary: Total Opioid Consumption in Morphine Equivalents Within 24 Hours After Surgery — 0; 10 mg morphine equivalents (MME)
N/A N=45 Yoga as an Intervention for Women With Knee Osteoarthritis
Osteoarthritis
Primary: Change in Knee Extensor Torque — 130.1 Nm
N/A N=28 Combined Application of Electrical Stimulated Antagonist Contraction During Walking (Walking Study)
Knee Osteoarthritis
Primary: Change in Knee Extensor Strength Assessed by Isokinetic Dynamometer. — 9.6; 3.8 Newton-meters (Nm)
N/A N=148 Pending Failure in Hard-hard Total Hip Arthroplasty
Infection and Inflammatory Reaction
Primary: Number of Participants With Chromium and Cobalt Ion Levels Above 7ug/l — 14; 0 participants above limit