Phase 4 N=350 A Trial of Oral Misoprostol for Labor Augmentation
Labor Augmentation
Primary: Uterine Tachysystole — 50; 41 participants
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Phase 4 N=1,003 Comparison of Low-dose and High-dose Oxytocin Regimens for Labor Augmentation
Dystocia
Primary: Number of Participants Delivered by Cesarean — 73; 72 Participants
N/A N=102 Comparison of Pre-Induction Cervical Ripening
Failed Labour
Primary: Vaginal Delivery — 20; 21; 20 participants
N/A N=2,227 Foley Bulb With Oral Misoprostol for Induction of Labor
Pregnancy · Labor, Induced
Primary: Number of Participants With Vaginal Delivery — 869; 860 Participants — p=0.86
Phase 4 N=170 Low-Dose Versus High-Dose Oxytocin Dosing for Induction and Augmentation of Labor
Labor Long
Primary: Time to Delivery — 1041.8; 971.1 minutes
N/A N=201 LaPPS: Labor Podcast for Patient Satisfaction
Labor Onset and Length Abnormalities · Pregnancy Related
Primary: Labor Agentry Scale — 57; 54 score on a scale
N/A N=80 Non-pharmacological Resources in Assisting Labor
Labour Pain
Primary: Pain Relief — 79.5; 73.8; 71.0; 51.7 millimeters
N/A N=818 Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
Labor Pain · Pregnancy
Primary: Delivered by Cesarean Section — 134; 126 participants — p=0.65
Phase 4 N=108 Pitocin or Oral Misoprostol for PROM IOL
PROM
Primary: Time From Induction of Labor (IOL) to Delivery — 18.1; 14.9 Hours
N/A N=197 Foley Bulb Traction for Cervical Ripening
Cervical Ripening · Induction of Labor
Primary: Time to Delivery — 19.8; 18.8 hours
Phase 4 N=117 Foley Bulb With Low Dose Pitocin Versus Foley Bulb With a Standard Incremental Infusion Protocol for the Induction of Labor
Induction of Labor
Primary: Time to the Second Stage of Labor — 18.2; 14.6 hours
N/A N=491 Foley OR MisO for the Management of Induction
Delivery; Prolonged
Primary: Time to Delivery — 13.1; 17.6; 17.7; 14.5 Hours
Phase 3 N=30 Mifepristone for Labor Induction
Induced Vaginal Delivery
Primary: Number of Uterine Contractions — 103; 112; 9; 15 contractions — p=0.44
N/A N=200 A Randomized Comparison of Transcervical Foley Bulb With Vaginal Misoprostol to Vaginal Misoprostol Alone for Induction of Labor
Pregnancy
Primary: The Time Interval From Induction to Delivery: All Participants — 20.97; 16.27 hours
Phase 3 N=180 Study of the Effectiveness of Cervical Ripening Balloon With and Without Oxytocin
Cervical Ripening · Induction of Labor · Multiparity
Primary: Time From Cervical Ripening to Delivery — 16.88; 13.13 hours
N/A N=26 Cervical Ripening With Cook Catheter Plus Low Dose Oxytocin
Cervical Ripening
Primary: Time to Delivery (in Hours) — 27; 23 hours — p=0.208
Phase 4 N=323 Foley With Oxytocin Versus Foley no Oxytocin for Induction of Labor
Labor; Forced or Induced, Affecting Fetus or Newborn
Primary: Delivery Rate — 40; 58; 48; 62 Participants
N/A N=348 Dental Support Device in the Second Stage of Labor
Labor
Primary: Dilation Duration of Second Stage of Labor Time — 82; 90 minutes
Phase 3 N=75 Comparing Bupivacaine, Lidocaine, and a Combination of Bupivacaine and Lidocaine for Labor Epidural Activation
Labor Pain
Primary: Time to Achieve an Adequate Epidural Level for Labor Analgesia — 7.0; 11.0; 8.5 minutes
N/A N=109 Pre-epidural Sequential Compression Devices (SCDs) to Prevent Hypotension During Labor
Hypotension · Labor Complication
Primary: Hypotension — 4; 4 participants
N/A N=129 Outpatient Foley For Starting Induction of Labor at TErm
Pregnancy
Primary: Total Time From Admission to Delivery — 13.5; 12.4 hours — p=0.38
N/A N=100 Patient Education on Labor Analgesia Options
Labor Analgesia
Primary: Survey to Determine Utility and Effect of Educational Materials — 79; 21; 93; 7 percentage of patients responding — p=<0.0001
Phase 4 N=41 Effect of Preemptive Epidural Analgesia in Labor on Cytokine Production
Obstetric Pain
Primary: Maternal Cytokine IL-10 Levels of pg/ml Upon Enrollment — 12.7; 14.2 pg/ml
N/A N=303 Acupuncture With Manual and Electrical Stimulation to Reduce Labour Pain
Labour Pain
Primary: Use of Epidural Analgesia — 99; 103; 101 participants
Phase 3 N=95 Labor and Delivery Implant Insertion: A Randomized Controlled Trial
Postpartum Contraception · Family Planning
Primary: Time to Lactogenesis Stage II [Questionnaire] — 65; 67.5 hours
N/A N=252 Induction of Labor With Oxytocin: When Should Oxytocin be Held?
Labor Induction · Cesarean Delivery
Primary: Cesarean Delivery — 32; 24 Cesarean deliveries
N/A N=134 Foley Catheter for Induction of Labor
Foley Catheterization · Induction of Labor · 5 French Stylette
Primary: Duration of Insertion Between Foley Catheter Groups With and Without a Stylette. — 1.72; 1.88; 6.55; 5.00 minutes — p=.70
N/A N=2,162 The Association Between Decreasing Labor Analgesia Epidural Infusion and Forceps Delivery
Labor Pain · Pregnancy
Primary: Number of Parturients With a Decrease in the Infusion of Epidural Analgesia During Second Stage of Labor — 146; 51 participants — p=<0.01
N/A N=35 Refinement of the OBMedical LaborView System
Fetal Monitoring
Primary: Fetal Heart Rate With the Laborview System Versus the CTG Monitor - Pilot Comparison Study — 5.282 beats per minute — p=<.1
N/A N=150 Early Amniotomy Following Transcervical Foley Balloon in the Induction of Labor
Labor Induction · Early Amniotomy
Primary: Time to Active Phase of Labor — 885; 975 minutes