N/A N=170 Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress
Acute Psychological Stress
Primary: Stressor-evoked Oxygen Consumption in mL/(kg·Min) (Stress - Baseline) — 0.265; 0.287 mL/(kg·min)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=121 Stress Management for Patients With Multiple Sclerosis
Multiple Sclerosis
Primary: No.of Gd+ Lesions From Week 8 to Week 24 — 46; 33; 5; 13 participants — p=0.04
N/A N=120 College Student Stress: Transitions Over Time
Depressive Symptoms
Primary: Percentage of Eligible Participants Who Agreed to Participate in the Trial — 120 Participants
N/A N=199 Caregiver Self-Management of Stress
Caregiver Distress · Job Stress
Primary: 10-item Kessler Psychological Distress Scale (K10) — 23.38; 23.79 score on a scale — p=0.513
N/A N=17 Daily Stress and Vascular Function in Midlife as a Risk Factor for Cognitive Decline
Middle-aged Adults · Major Depressive Disorder
Primary: Nitric Oxide (NO)-Mediated Endothelium-dependent Dilation (EDD) — 70; 74 percentage — p=>0.05
N/A N=94 Stress and the Sympathetic Nervous System in Adults With Depression
Major Depressive Disorder
Primary: Percent of Days Participants Report Stressors — 36; 40 percent of days
N/A N=50 Comparison of Two Behavioral Treatments for Stress Reduction
Stress
Primary: Brain Activity (fMRI) During the Body Scan Meditation — 74; 82 voxels
N/A N=1,418 Effects of Arousal and Stress in Anxiety
Healthy Volunteers
Primary: Go Correct Hits Followed by Button Press — 90.9; 91.6 Percentage of correct responses
N/A N=81 Ecological Momentary Assessment and Text Message Intervention for Stress Management
Stress, Psychological · Loneliness · Covid19
Primary: Number of Participants Who Completed EMA and EMA Plus Text Message Intervention or EMA Intervention Alone. — 39; 42 Participants
N/A N=53 Stress in Inflammatory Bowel Disease
Inflammatory Bowel Diseases · Psychological
Primary: Retention Rate — 23; 25; 19; 22 Participants
N/A N=179 Mobile Self-Management Program for Stress Reduction in Young Adults
Stress (Psychology)
Primary: Stress at Week 8 — 19.41; 18.35 score on a scale
Phase 4 N=226 Stress Neuroadaptation in Tobacco Dependence
Nicotine Dependence
Primary: Overall Stressor Reactivity — 25.1; 22.5; 32.3; 16.9 microvolts
N/A N=42 HEALTHY (Health Education Adolescent Leadership Training to Help Youth) Leaders
Stress
Primary: Number of Participants Reporting Pediatric Symptoms as Assessed by the Pediatric Symptom Checklist-17 (PSC-17) — 3; 2; 4; 3 participants
N/A N=295 Involuntary Childlessness and Stress Management
Infertility
Primary: The Effect of Expressive Writing Intervention on Fertility Related Stress — 17.2; 15.7; 17.4; 17.1 units on a scale — p=<0.05
N/A N=217 Breathe With Ease: A Unique Approach to Managing Stress (BEAMS)
Asthma
Primary: Symptom-free Days in the Last 14 Days — 11.4; 11.6 days in prior 14d — p=0.93
N/A N=72 Biological Response to Brief Psychological Challenge
Acute Inflammatory Response to Psychological Stress
Primary: Cell-free Mitochondrial DNA — 165.79; 405.56; 175.45; 164.45 Copies per uL — p=0.86
Phase 2 N=43 Family-Focused, Stress-Reduction Program to Improve the Health Care of Urban Children With Asthma
Asthma
Primary: Mean Score on the Family Asthma Management System Scale (FAMSS) — 4.9; 4.1 units on a scale — p=0.23
N/A N=119 Stress Response in Opioid Use Disorder
Opioid-use Disorder
Primary: Change in Negative Affect — 1.67; 1.25; 3.60 scores on a scale
N/A N=28 Stress and Hypertension in Dementia Caregivers
Hypertension · Stress, Psychological
Primary: Change in Blood Pressure (Systolic) — 129; 127; 122; 124 mmHg
N/A N=13 Video Based Mindfulness Based Stress Reduction
Parkinson's Disease
Primary: Salivary Cortisol Levels (Pre- and Post-) Mindfulness-Based Stress Reduction Program — -33.1 Concentration (ng/mL)
N/A N=50 Stress and CKD Among African Americans
Chronic Kidney Disease
Primary: Change in Subjective Units of Distress Scale (SUDS) Score — 2.92; 3.12 score on a scale
Phase 2 N=212 Personalized Trials for Stress Management Against Standard of Care
Stress
Primary: Between-Arm Difference in Change in Ecological Momentary Assessment (EMA) of Stress. — -0.50; -0.31 units on a scale — p=.316
N/A N=58 Cranial Electrotherapy Stimulation and Acute Stress
Anxiety State
Primary: Change From Baseline in Heart Rate During Stressful Lethal Force Decision Making Task — 98.5; 111; 100.0; 114 bpm — p=.012
N/A N=308 Middle School Success Over Stress
Parenting · Parent-Child Relations · Depression
Primary: Change From Baseline in Parent Mental Health and Well-being (Parent Report) — .7442; .7523; .6484; .5571 score on a scale — p=.548
N/A N=164 Mindful Hearts Study: Mindfulness to Reduce Stress
Cardiovascular Disease · Psychological Stress · Stroke
Primary: Perceived Stress — 15.94; 15.50 score on a scale
N/A N=28 Resolving Psychological Stress
Post-Traumatic Stress Disorder · Alcohol Use Disorder
Primary: PTSD Symptoms Using PTSD Checklist-5 (PCL-5) at Baseline and 15 Days — 33.2; 36.6; 31.2; 28.2 units on a scale — p=0.322
N/A N=52 Stress-reduction Wellness Program for Midlife Black Women (B-SWELL)
Cardiovascular Risk Factor · Stress · Self Efficacy
Primary: American Heart Association's Life's Simple Seven (LS7) Score — 8.76; 8.21 units on a scale
N/A N=53 Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adversity
Stress · Psychological Stress · Child Maltreatment
Primary: Change in Stressor Demands, as Measured by Ecological Momentary Assessment (EMA) — -.0950; .0009 score on a scale
N/A N=40 Mindfulness for Resilience in Early Life
Adolescent With Early Life Stress · Resilience
Primary: Cortisol Reactivity — -0.21; 0.34; 0.05; -0.08 μg/dL — p=<.05
N/A N=210 Physical Health in Midlife: Influences of Adversity and Relationships Over Time
Cardiovascular Disease · Type 2 Diabetes
Primary: Hormonal Levels — 910000; 5.8; 22.8; 171.8 ng/ml