N/A N=259 Study Comparing 3 Different Treatments for Arthritis of the Lower Back (Lumbar Spinal Stenosis)
Lumbar Spinal Stenosis
Primary: Swiss Spinal Stenosis (SSS) Questionnaire Score — -2.0; -1.7; -4.1 units on a scale — p=0.73
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=250 The Glucosamine-study: The Effect of Glucosamine in Treatment of Chronic Low Back Pain
Low Back Pain
Primary: Roland Morris Disability Questionnaire — 9; 9 units on a scale (0-24) — p=0.05
N/A N=196 Efficacy of Acupuncture for Lumbar Spinal Stenosis
Lumbar Spinal Stenosis · Intermittent Claudication
Primary: The Change in Modified Roland-Morris Disability Questionnaire (RMDQ) Score From Baseline — -4.3; -3.0 score on a scale
N/A N=80 Knee Bracing for People With Patellofemoral Osteoarthritis
Knee Osteoarthritis
Primary: Change in Pain on the VIsual Analog Scale (VAS) — -.068 change in units on a scale from baseline
N/A N=184 Manual Therapy and Strengthening for the Hip in Older Adults With Chronic Low Back Pain
Chronic Low-back Pain · Hip Impairments · Hip-spine Syndrome
Primary: Quebec Back Pain Disability Scale — 27.9; 27.9; 16.7; 20.3 score on a scale
N/A N=59 Benefit of Lumbar Bracing for Chronic Low Back Pain Due to Degenerative Disc Disease
Degenerative Disc Disease · Lumbar Spondylosis · Low Back Pain
Primary: Pain Diary — 6.71; 5 units on a scale
N/A N=40 Muscle Property, Alignment and Joint Loading in People With Knee Osteoarthritis
Osteoarthritis, Knee
Primary: Change of External Knee Adduction Moment as Assessed by Visual Motion Analysis System — 0.50 Nm/kg
N/A N=145 Low-level Laser Therapy and Static Stretching in Knee Osteoarthritis.
Osteoarthritis, Knee
Primary: Change From Baseline in Visual Analogue Scale for Pain — 3.2; 3.8; 3.1; 3.3 units on a scale
Phase 3 N=455 Osteopathic Health Outcomes in Chronic Low Back Pain (OSTEOPATHIC) Trial
Low Back Pain
Primary: Change in Visual Analogue Scale Score for Pain Over 12 Weeks (OMT vs Sham OMT) — 40; 20 participants — p=0.007
N/A N=50 Osteoarthritis Structural Changes Assessed by Magnetic Resonance Imaging and Neuropathic Pain in Knee Osteoarthritis
Neuropathic Pain · Knee Osteoarthritis
Primary: Osteoarthritis Structural Changes Assessed by Quantitative Magnetic Resonance Imaging With and Without Neuropathic Pain — 14; 7; 5; 1 participants
N/A N=41 Hip Osteoarthritis: Effects of Exercise Programs on Pain and Disability
Hip Osteoarthritis
Primary: Change in 6-minute Walk Test — 22; 49 meters
N/A N=178 Lumbar Degenerative Disc Disease Treated With Anterior Tension Band System (ATB) With ALIF/FRA Spacer
Lumbar Degenerative Disc Disease
Primary: Number of Subjects With Successful Radiographic Fusion — 90 Participants
N/A N=54 Effect of Lumbar Bracing on Spinal Function
Low Back Pain
Primary: Oswestry Disability Index — .42; .83; 10.41; .42 score on a scale
Phase 2 N=41 A Pilot Study Assessing the Treatment Responsiveness of a Novel Osteoarthritis Stiffness Scale
Osteoarthritis, Knee
Primary: Sum of Change in Brief Arthritis Stiffness Scale (BASS) Scores Over the 4-day Treatment Period — -12.6; -13.6; -11.7; -2.3 Scores on a scale
Phase 2 N=75 Safety and Efficacy of XT-150 for Facet Joint Osteoarthritis Pain
Facet Joint Pain · Back Pain · Inflammation
Primary: Number of Participants Reporting Serious Adverse Events (SAEs) and Non-SAEs — 11; 12; 14; 14 Participants
Phase 4 N=29 Lumbar Stenosis Outcomes Research (LUSTOR)
Lumbar Spinal Stenosis
Primary: Time to First Symptoms of Moderate Pain — 2.52; 3.06 minutes
Phase 2 N=200 Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Knee Pain Related to Osteoarthritis
Osteo Arthritis Knee · Arthritis
Primary: Change in Pain Units on a Scale (0-10) 0 Being Least, 10 Being Worst Pain (Value at 8 Weeks Minus Value at Baseline). — -3.7; -3.02; -1.61 units on a scale
N/A N=376 Activ-L™ Artificial Disc Treatment of Degenerative Disc Disease in the Treatment of Degenerative Disc Disease
Degenerative Disc Disease
Primary: Overall Success at 24 Months Relative to Baseline — 42.2; 28.3; 61.9; 52.8 percentage of participants — p=<0.05
N/A N=45 Yoga as an Intervention for Women With Knee Osteoarthritis
Osteoarthritis
Primary: Change in Knee Extensor Torque — 130.1 Nm
N/A N=100 Sagittal Plane Shear Index for Planning Lumbar Stenosis Surgery
Lumbar Spinal Stenosis · Spondylolisthesis
Primary: Proportion of Surgical Plans Recorded Prior to the SPSI Report That Are Altered After Integration of SPSI Into the Surgical Planning — 47; 22; 6 Surgical plans
N/A N=10 FDG PET/MRI Evaluation of Facet Joint Pain
Low Back Pain
Primary: Facet Joint High Grade FDG Activity Concordance to Pain — 0.10 concordance correlation coefficient
N/A N=75 Gait in Low Back Pain Patients After Spinal Mobilization
Chronic Low Back Pain
Primary: Change in the Numerical Pain Rating Scale — 5.96; 6.12; 6; 1.22 units on a scale
N/A N=15 Treatment of Symptomatic Lumbar Internal Disc Disruption (IDD) With the Biostat® Disc Augmentation System: A Pilot Study
Low Back Pain
Primary: Numbers and Types of Adverse Events (Only Number of Events is Reported in This Section - See Adverse Events Section for Further Detail) — 17 Events
N/A N=3,000 Development of an Osteoarthritis (OA) Care Plan to Improve Process and Quality of OA Treatment Decisions
Osteo Arthritis Knee · Osteoarthritis, Hip
Primary: Differences in Decision Conflict Scale With ASK vs Usual Care — 25.1; 26.0 Score on a scale
N/A N=300 Patient and Provider Interventions for Managing Osteoarthritis in Primary Care
Osteoarthritis
Primary: Western Ontario and McMasters Universities Osteoarthritis Index (WOMAC) — 48.4; 48.4; 43.5; 41.2 units on a scale — p=0.158
N/A N=93 Wearable LITUS Device for Osteoarthritis of the Knee: a Randomized Double-Blind Placebo-Controlled Trial
Knee Osteoarthritis
Primary: Pain on the Numeric Rating Scale (NRS) Change From Baseline to Study Conclusion — -1.96; -0.85 units on a scale
Phase 2 N=32 Intradiscal rhGDF-5 Phase I/II Clinical Trial
Degenerative Disc Disease
Primary: Neurological Assessment for Motor Function and Reflexes/Sensory — 0; 0 participants
N/A N=416 Flares of Low Back Pain With Activity Research Study
Low Back Pain
Primary: Participant-reported "Flares" of Low Back Pain (Aim 1) — 7.3 Mean flares per year
Phase 4 N=40 Duloxetine in Osteoarthritis (OA) Pain
Osteoarthritis
Primary: Change in Brain Gray Matter Volume — -0.34; -0.92 percentage of change
Phase 3 N=401 Corticosteroid Lumbar Epidural Analgesia for Radiculopathy
Lumbosacral Radicular Pain
Primary: Mean Change From Baseline (Day 1) to Week 4 in the Mean Numeric Pain Rating Scale (NPRS) Average Pain Score in the Affected Leg — -2.34; -1.16 Change in score on a scale…