N/A N=995 Neonatal Outcome by Reason for Delivery
Preterm Delivery
Primary: Composite Perinatal Morbidity — 277; 203; 221; 45 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=230 Cervical Ripening in Premature Rupture of Membranes
Pregnancy · Premature Rupture of Membranes · Preterm Premature Rupture of Membranes
Primary: Rate of Cesarean Section — 27; 26; 89; 86 participants — p=0.99
Phase 4 N=108 Pitocin or Oral Misoprostol for PROM IOL
PROM
Primary: Time From Induction of Labor (IOL) to Delivery — 18.1; 14.9 Hours
N/A N=20 Cervix Monitor for Elasticity and Length Measurements
Preterm Birth
Primary: Cervix Elasticity — 54; 19.7 kPa
N/A N=301 Tocolysis for Preterm Labor
Preterm Labor
Primary: The Primary Outcome Measure of This Research is to Compare the Efficacy of the Three Clinically Used Tocolytic Agents in a Prospective Study That Will Allow Direct…
Phase 2 N=29 The Safety, Tolerability And Metabolism Of GSK221149A, In Pregnant Women (30-36 Weeks), In Pre-Term Labor
Obstetric Labour, Premature
Primary: Number of Participants With Vital Sign Values of Potential Clinical Concern — 2; 4; 0; 3 Participants
Phase 2 N=21 Progesterone for the Management of Preterm, Premature Rupture of the Membranes: A Randomized Controlled Trial.
Pregnancy Complications
Primary: Number of Participants With Achievement of 34 Weeks Gestation — 0; 0 Participants
N/A N=144 The Use of Progesterone to Reduce Preterm Birth
Preterm Birth
Primary: Weeks Gestation at Birth Among Patients Receiving the Active Drug. — 31.9; 30.2 weeks
N/A N=122 Prevention of Preterm Birth With a Pessary in Singleton Gestations
Preterm Birth · Short Cervix
Primary: Number of Subjects Experiencing Preterm Birth — 26; 23 Participants
Phase 3 N=88 Nifedipine for Acute Tocolysis of Preterm Labor
Preterm Labor
Primary: Number of Participants With Preterm Birth — 24; 20 Participants
N/A N=46 Prevention of Preterm Birth With a Pessary in Twin Gestations
Premature Birth · Short Cervix
Primary: Number of Participants With Preterm Delivery — 9; 8 Participants
Phase 3 N=152 Progesterone (17P, Makena®) for Prolongation of Pregnancy in Women With Preterm Rupture of the Membranes (PROM)
Preterm Delivery
Primary: Gestational Age at Delivery — 29.2; 29.5 weeks.
Phase 3 N=2,831 Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial
Pregnancy · Respiratory Distress Syndrome · Pregnancy Outcomes
Primary: Neonatal Composite Outcome — 165; 202; 145; 184 Participants — p=0.02
Phase 2 N=482 Reducing Preterm Births in Underserved Pregnant Women
Preterm Birth · Low Birth Weight <2500 Grams · Verylow Birthweight <1500 Grams
Primary: Birthweight — 40; 26 participants
N/A N=110 Ultrasound Prediction of Prolonged Labour
Prolonged Labor
Primary: Area Under the Receiver Operating Curve (ROC AUC) Values for Prediction of Vaginal Delivery Using 2D or 3D Ulrasound — 81; 76; 80; 76 percentage probability — p=<0.01
N/A N=175 Preemie Prep For Parents (P3): Home Antenatal Prematurity Education
Premature Birth · Decision Making · Prenatal Care
Primary: Parent Prematurity Knowledge Questionnaire — 30.3; 22.8; 29.3; 25.6 score on a scale
N/A N=8 Pilot Study to Evaluate a Prototype Electronic Uterine Inhibitor to Prevent Preterm Contractions
Preterm Birth
Primary: Uterine Contractions — 3.18; 3.78; 3.20 minutes
N/A N=102 Comparison of Pre-Induction Cervical Ripening
Failed Labour
Primary: Vaginal Delivery — 20; 21; 20 participants
N/A N=584 Transperineal Ultrasound to Assess the Progress of Labour
Placenta Praevia · Vaginismus
Primary: Caesarean Delivery — 79 Participants
Phase 4 N=236 Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness Trial
Obesity · Labor Induction · Cesarean Delivery
Primary: Number of Participants With a Need for Cesarean Delivery — 51; 53 Participants
N/A N=201 LaPPS: Labor Podcast for Patient Satisfaction
Labor Onset and Length Abnormalities · Pregnancy Related
Primary: Labor Agentry Scale — 57; 54 score on a scale
Phase 2 N=271 Efficacy Study of a Cervical Pessary Containing Progesterone for the Prevention of Preterm Delivery
Preterm Birth
Primary: Number of Participants Not Giving Birth Before Week 32 and Week 34 of Gestation — 73; 71; 67; 66 Participants
Phase 3 N=180 Study of the Effectiveness of Cervical Ripening Balloon With and Without Oxytocin
Cervical Ripening · Induction of Labor · Multiparity
Primary: Time From Cervical Ripening to Delivery — 16.88; 13.13 hours
Phase 3 N=321 17OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet Pregnancies
Preterm Birth
Primary: Newborn Respiratory Distress Syndrome (RDS) — 44; 18 Twins
N/A N=2,227 Foley Bulb With Oral Misoprostol for Induction of Labor
Pregnancy · Labor, Induced
Primary: Number of Participants With Vaginal Delivery — 869; 860 Participants — p=0.86
N/A N=36 Comparison of Nifedipine Versus Indomethacin for Acute Preterm Labor
Obstetric Labor, Premature
Primary: Number of Participants With Delay of Preterm Delivery by 48 Hours. — 15; 21 Participants
Phase 4 N=350 A Trial of Oral Misoprostol for Labor Augmentation
Labor Augmentation
Primary: Uterine Tachysystole — 50; 41 participants
N/A N=150 Prediction of Delivery With Transperineal Ultrasound in Women With Prolonged Labour. Multicentre Study
Failed Labor
Primary: Percentage of Women With Vaginal Deliveries — 92; 52; 88; 57 percentage of participants in each group — p=<0.01
Phase 3 N=30 Mifepristone for Labor Induction
Induced Vaginal Delivery
Primary: Number of Uterine Contractions — 103; 112; 9; 15 contractions — p=0.44
Phase 2 N=10 Indomethacin Versus Nifedipine for Preterm Labor Tocolysis
Obstetric Labor, Premature
Primary: Count of Patients With Recurrent Preterm Labor Within Two Weeks of Randomization — 2; 1 Participants — p=0.004