Clinical Trial Search

Primary: Number of Participants With a Negative Obstructive Sleep Apnea (OSA) Home Sleep Test Result — 61 Participants

Primary: Participant Providing Feedback — 26 Participants

Primary: Apnea-hypopnea Index (AHI) at One Year — 35.3; 39.6 events per hour

Primary: Model Prediction of Absence/Presence of OSA: Ventilation That Causes an Arousal From Sleep (Varousal) — 5.7; 5.2 L/min — p=0.05

Primary: Positive Berlin Questionnaire Indicative of Sleep Disordered Breathing — 1343; 96 participants — p=0.001

Primary: Inflammation — -11.47; -37.45; -32.66 percentage of change in crp at week 24

Primary: Change of Daytime Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) Pre-treatment and Post-treatment — -8; -3; -4; -3 mm Hg — p=<0.05

Primary: Apnea Hypopnea Index (AHI, Events/Hour of Sleep) — 33; 20.4 events/hour of sleep — p=0.47

Primary: Flow Mediated Dilation — 5.7; 9.5; 7.3 percentage change of vessel diamter — p=0.02

Primary: Apnea Hypopnea Index (AHI, Events/Hour of Sleep) — 21.6; 37.9 events/hour of sleep — p=0.56

Primary: Subjective Sleepiness — 11.8; 10.2; 9.9 units on a scale

Primary: Ventilation (Aim 1) — 1.19; 1.14; 1.35; 1.16 fraction of baseline — p=0.001

Primary: Compliance of Auto-CPAP Therapy — 41.8; 39.7 percentage of nights

Primary: Apnea Hypopnea Index — 42.71; 40.95 Apneas or hypopneas per hour sleep

Primary: Insomnia Severity Index Score — -8.2; -7.33; -6.27 score on a scale — p=0.8

Primary: Change in Number of Subjects Without Oxygenation Abnormalities — 12; 10 Participants — p=0.54

Primary: Left Ventricular Ejection Fraction Improvement — 4.5; -.3 percent change

Primary: Apnea Hypopnea Index - Crossover — 34.9; 39.6 units on a scale

Primary: Prevalence of Obstructive Sleep Apnea Syndrome in Chinese Elderly — 15 % of participants — p=<0.05

Primary: Fat Mass (% of Total Body Mass) — 40.0; 37.7; 38.7; 38.6 percentage of total body mass

Primary: Change in AHI — 45; -15.8 events/h

Primary: Change From Baseline in 24-hour Blood Pressure at Months 6 and 12 by Pooled Arms — 1.82; 1.06; 0.59; -0.73 mmHg

Primary: CPAP Adherence — 2.8; 3.9 hours per night — p=0.001

Primary: Objective Sleep Parameters

Primary: Change in Continuous Glucose Monitoring System Standard Deviation — 0.8; 1.1 mg/dL

Primary: Change in Apnea-hypopnea Index (AHI) Outcome Measure in Response to Pioglitazone or Placebo — 35.8; 34.4 AHI events/hour

Primary: Correlation Between the Trial Device and an Established Device — 0.955 correlation coefficient

Primary: Respiratory Event Index (REI) at T2 — 12.8; 21.1; 9.3; 13.1 number of events per hour — p=0.152

Primary: Apnea-Hypopnea Index — 38.7; 28.5 events/hour

Primary: Effect of CPAP on Neurocognitive Function: E/F Function- SWMT-OMD — 0.035; -0.074; 0.072; 0.018 score on a scale — p=0.0074