N/A N=90 Donor After Circulatory Death Heart CAP Trial
Heart Transplant
Primary: Patient Survival — 75 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=180 Donors After Circulatory Death Heart Trial
Heart Transplant
Primary: Survival — 76; 75 Participants — p=<0.0001
N/A N=429 Intervention to Motivate Teens to be a Designated Organ Donor on Driver's License
Tissue and Organ Procurement · Alcohol Abstinence
Primary: Designated Organ Donor Status on Driver's License — 67; 38 participants
N/A N=321 Remote Ischemic Preconditioning in Neurological Death Organ Donors
Organ Transplantation
Primary: Number of Organs Recovered Per Donor — 3.79; 3.60 organs recovered per donor — p=0.38
N/A N=273 A Randomized Trial of the Early Referral and Request Approach (ERRA) Intervention to Increase Consent to Organ Donation
Organ Donation
Primary: Change in Authorization Rates for Solid Organ Donation From Families of Donor-eligible Patients — 78; 80; 89; 81 Percentage of successful requests
Phase 3 N=838 Intravenous Thyroxine for Heart-Eligible Organ Donors
Brain Death · Heart Failure
Primary: Heart Transplanted — 230; 223 Participants — p=0.57
N/A N=300 Transplant Social Worker Support for Live Kidney Donation in African Americans
Kidney Disease
Primary: Number of Participants With Live Kidney Donor Activation Events — 87; 86; 88; 5 Participants
N/A N=105 Conventional Laparoscopic Versus Laparoendoscopic Single Site Donor Nephrectomy in Living Donor Kidney Transplantation
Living Donors · Nephrectomy · Kidney Transplantation
Primary: The Primary End Point of the Study Was the Mean/Median Number of Days Postsurgery Required for Each Group to Return to 100% Functioning Capacity. — 43; 45 days
N/A N=784 Healthcare Utilization in Obese Caregiver Living Donors
Utilization, Health Care · Obesity
Primary: Emergency Department Utilization — 77; 305 Participants
N/A N=103 Enhancing Donated After Cardiac Death (DCD) Utilization With Thrombolytic Therapy
Liver Transplantation · Kidney Transplantation
Primary: Delayed Kidney Graft Function — 5; 7 Participants
N/A N=105 Don't Throw Your Heart Away: Medical Student Study 2
Cardiac Transplant Disorder
Primary: Hospital Choice — 33; 47; 23; 2 Participants
Phase 3 N=199 Naloxone for Optimizing Hypoxemia Of Lung Donors
Brain Death · Organ Donors · Lung Transplantation
Primary: Change in Oxygenation (P/F Ratio) From Baseline to Final Pre-recovery Arterial Blood Gas (ABG) — 81; 80 mm Hg
N/A N=1,019 Don't Throw Your Heart Away: Layperson Study 1
Cardiac Transplant Disorder
Primary: Hospital Choice — 64; 125; 163; 192 Participants
N/A N=3 Robotic Single Port Donor Nephrectomy
Renal Transplant Donor of Left Kidney · Donor Nephrectomy · Robotic Surgery
Primary: Successful Completion of the Surgical Procedure — 3 Participants
N/A N=72 Don't Throw Your Heart Away: Clinician Study 3
Cardiac Transplant Disorder
Primary: Hospital Choice — 4; 21; 34; 13 Participants
N/A N=1,090 Cornea Donor Study
Corneal Disease · Fuch's Dystrophy · Pseudophakic Corneal Edema
Primary: Graft Failure — 142; 82 participants
Phase 2 N=506 The Effect of Nebulized Albuterol on Donor Oxygenation
Brain Death · Organ Donor · Pulmonary Edema
Primary: Donor Oxygenation — 49; 40 cmH2O — p=0.98
N/A N=416 Reducing Disparities in Living Donor Transplant Among African Americans
Kidney Transplant
Primary: Percent of Patients With at Least One Inquiry From a Potential Living Donor — 15.63; 15.63; 15.77; 15.87 percentage of participants
Phase 2 N=16 DCreg in Living Donor Liver Transplantation
Living Donor Liver Transplantation
Primary: Proportion of Safety Events — 1 Participants
N/A N=361 Motivations to Transplant Registry Participation
Healthy
Primary: Intention to Register — 3.32; 3.06; 4.15; 3.27 score on a scale — p=.001
N/A N=36 Nutritional Status and Enteral Absorption Capability After Brain Death
Brain Death
Primary: Primary Outcome Measure is IL-6 Level — 565.5; 264.9 pg/ml
N/A N=300 OCS Liver PROTECT Trial: Preserving and Assessing Donor Livers for Transplantation
Liver Transplantation · Liver Preservation for Transplant
Primary: Participants With Early Liver Allograft Dysfunction (EAD) — 27; 44; 27; 47 Participants — p=<0.0001
N/A N=422 Increasing Live Donor Kidney Transplantation Through Video-based Education and Mobile Communication
End-stage Renal Disease · Chronic Kidney Diseases
Primary: Living Donor Inquiry — 16.0; 18.6 Percentage of participants — p=0.507
N/A N=121 Remote Ischemic Conditioning (RIC) in Recipients of Brain Death Donor Livers - A Feasibility and Safety Study
Liver Failure · Carcinoma, Hepatocellular
Primary: Percentage of Participants Completing Entire Intervention Protocol — 70.96 percentage of participants
Phase 2 N=100 Evaluation of Donor Specific Immune Senescence and Exhaustion as Biomarkers of Tolerance Post Liver Transplantation
Liver Transplant · Liver Transplantation
Primary: The Percent of Participants Who Achieve Operational Tolerance 52 Weeks After Completion of Immunosuppression Withdrawal. — 16.4 Percent of Participants
N/A N=320 International Randomized Study of the TransMedics Organ Care System (OCS Lung) for Lung Preservation and Transplantation
Lung Preservation
Primary: A Composite of Patient Survival at Day 30 Post Transplantation, and Absence of International Society for Heart & Lung Transplantation (ISHLT) Primary Graft Dysfunction…
N/A N=75 International EXPAND Heart Pivotal Trial
Heart Transplant
Primary: Patient Survival at Day-30 Post Transplant and Absence of Severe Primary Heart Graft Dysfunction in the First 24 Hours Post-transplantation — 66 Participants — p=<0.0001
Phase 4 N=64 Tissue Glue (Cyanoacrylate) Versus Conventional Suture in Kidney Donors
Skin Closure of Surgical Incisions by Tissue Glue vs Suture
Primary: Wound Healing by Numerical Scales for Rubor Postoperative Day 2. — 0.516; 0.984 units on a scale
Phase 4 N=30 Multi-center Study to Transplant Hepatitis-C Infected Kidneys
Renal Failure Chronic · Hepatitis C
Primary: Number of Participants With Undetectable HCV — 30 Participants
N/A N=24 Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability
Emphysema · Chronic Obstructive Pulmonary Disease (COPD) · Cystic Fibrosis
Primary: 30 Day Mortality and Graft Survival — 0; 22; 0; 2 Participants