Phase 4 N=100 Efficacy of Tranexamic Acid in Foot and Ankle Surgeries
Foot and Ankle Surgeries · Bunion
Primary: Total Estimated Blood Loss — 40.41; 18.75 ml
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=35 Comparison of Non-Surgical Treatment Options for Chronic Exertional Compartment Syndrome (CECS)
Chronic Exertional Compartment Syndrome
Primary: University of Wisconsin Running Injury and Recovery Index Score at Baseline — 10.86; 11.86; 12.14; 9.75 cumulative score on a 9-item scale
N/A N=148 A Longitudinal Outcomes Study of the Subchondroplasty® Procedure in the Foot/Ankle
Insufficiency Fractures · Stress Fracture · Stress Fracture, Ankle, Foot and Toes
Primary: Foot Function Index-Revised (FFI-R) Short Form Score at 24 Months — 42.8; 43.0; 39.6 Percentage scale
N/A N=15 ICG Fluorescence Imaging in Lower Extremity Amputation Patients
Trauma Injury
Primary: Total Bone Blood Flow (TBBF)-Post Osteotomy — 4.9 mL/min/100g
N/A N=48 Prospective Subtalar, Double, or Triple Arthrodesis Study With CCS Screws
Post-traumatic Osteoarthritis, Unspecified Ankle and Foot · Localized, Primary Osteoarthritis of the Ankle and/or Foot
Primary: Number of Participants With Intraoperative Complications — 0 Participants
N/A N=38 Wedged Orthoses and Knee Osteoarthritis
Knee Osteoarthritis
Primary: Knee Adduction Moment at Baseline — 0.376; 0.342 Nm/(kg-m)
N/A N=30 Observational Study on JuniOrtho Plating System for Deformities and Fractures Treatment in Lower Limb
Deformity · Defect, Congenital · Trauma
Primary: Percentage (%) of Subjects With at Least One Serious/Not Serious Adverse Event Certainly Related or Possibly Related to JPS (ADEs) — 3.3 percentage of subjects
N/A N=30 Investigating Outcomes of Lower Limb Trauma
Trauma
Primary: Functional Outcome (Consisting of Questionnaire Score, Hamlyn Mobility Score (HMS) Gait/Activities of Daily Living Parameters) — 19.7; 58.2 units on a scale
N/A N=233 A Multicenter Randomized Trial Comparing Antiglide and Lateral Plate Fixation in Ankle Fractures
Ankle Injuries
Primary: Percentage of Nonpalpable Hardware — 71; 55; 64; 66 percentage of participants
N/A N=107 Study of an Orthotic Designed to Equalize Leg Lengths for Patients With Injuries Managed in Walking Boots
Joint Pain · Trouble Balancing
Primary: Patient Reported Balance — 3.0; 2.1 units on a scale
N/A N=50 Agility LP Ankle Arthroplasty Outcomes
Rheumatoid Arthritis of Ankle · Osteoarthritis of Ankle · Traumatic Arthritis of Ankle
Primary: Assessment of Functional Outcomes Following Agility LP Ankle Replacement — 37.67; 37.07 Degrees
N/A N=53 Immediate Weight Bearing Versus Protected Weight Bearing in Supracondylar Distal Femur Fractures
Closed Supracondylar Fracture of Femur
Primary: Time to Distal Femur Fracture Healing by Radiographic Evidence — 1.75; 2.15 months
Phase 4 N=190 Effects of a Surgical Site Injection on Pain Scores and Narcotic Use After Orthopaedic Trauma Surgery
Pertrochanteric Fracture
Primary: Amount (mg) of Narcotics (Oral Morphine mg Equivalents) Used — 16; 10 morphine milligram equivalents (MME)
N/A N=15 Functional Movement Retraining After Hip Replacement
Arthroplasty, Replacement, Hip
Primary: Change in Hip Disability and Osteoarthritis Outcomes Score (HOOS) - Activities of Daily Living Scale — -6.00 units on a scale
N/A N=50 Ankle Foot Orthosis Comparative Effect
Foot Injuries and Disorders
Primary: PROMIS Patient Reported Outcomes for Physical Function — 44.78; 45.02 score on a scale
N/A N=20 Heel Wedges and Carbon Fiber Custom Dynamic Orthoses to Control Knee Biomechanics
Adult ALL · Healthy
Primary: Knee Range of Motion — 69.1; 67.0; 66.4; 66.1 degrees
N/A N=25 TOKA: Custom Made Devices for High Tibial Osteotomy (HTO) - Clinical Investigation
Unicompartmental Medial Knee Osteoarthritis
Primary: Morphology Assessment Via Correction Angle Assessment — 1.5 Degree
N/A N=21 Internal Brace Augmented Anterior Inferior Tibiofibular Ligament Repair: Post-operative Syndesmotic Volumes.
Syndesmotic Injuries · Ligament Rupture · Bimalleolar Fractures
Primary: Syndesmotic Volumetric Ratio — 1.2; 1.1 Volumetric Ratio
N/A N=80 Custom Molded Foot Orthoses Effect on Foot Kinematics and Lower Extremity Electromyography During Walking and Running.
Lower Extremity Pain of a Mechanical Origin
Primary: Maximum Rearfoot Eversion Motion During Stance — 1.1; 1.1; 2.9; 3.0 Degrees — p=> .10
N/A N=80 Surgical Treatment of Hip Fractures Under Peripheral Regional Anesthesia
Hip Fractures
Primary: Success Rate (Supplemental Medication) — 22; 20; 3 Participants
N/A N=116 Implementation of Telemedicine for Patient With Lower Extremity Wounds
Peripheral Arterial Disease · Peripheral Artery Disease · Peripheral Vascular Diseases
Primary: Specialty Consultation — 66 days
N/A N=100 Compass Hinge Stabilization of Knee Dislocations: A Randomized Trial
Knee Dislocation
Primary: Knee Stability — 29; 26; 12; 17 participants
N/A N=84 Clinical Evaluation of the OrthoPAT Advance System
Transmission, Blood, Recipient/Donor
Primary: Washed RBC Hematocrit — 55.43; 56.48 percentage of HcT
N/A N=22 Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress
Ankle Fractures · Post-traumatic Osteoarthritis · Osteoarthritis Ankle
Primary: Joint Contact Stress Time Exposure (Model Estimated) — 4.44; 3.97; 4.08; 4.25 MPa-s/gait cycle
N/A N=273 Treatment Outcomes for Ankle Arthritis
Osteoarthritis
Primary: Musculoskeletal Functional Assessment (MFA) — -12.5; -15.0 units on a scale
N/A N=80 A Physical Therapy Program Versus Surgery for Femoroacetabular Impingement: Randomized Clinical Trial
Femoroacetabular Impingement
Primary: Hip Outcome Score - ADL Subscale at 24 Months — 69.3; 73.1 score on a scale
Phase 4 N=70 Knee Arthroplasty Performed With Conventional and Customized Instrumentation
Knee Arthritis
Primary: Length of Surgery — 3447.19; 3707.19 seconds
N/A N=95 Pelvis RCT: Impact of Surgery on Pain in Lateral Compression Type Pelvic Fractures
LC Pelvic Fracture
Primary: Posttreatment Pain — 5.3; 6.2; 4.2; 5.6 scores on a scale
N/A N=124 Ambispective, Multicentre, Open-label Study Evaluating the Clinical Outcomes of Foot Surgery Using SERF Medical Devices
Foot Diseases
Primary: Reduction of the Patient's Pain and Restoration of Walking — 42.46; 88.44 points
N/A N=14 Spring Loaded Tri-Compartment Unloader Knee Brace Study
Anterior Knee Pain
Primary: Knee Injury and Osteoarthritis Outcome Score (KOOS) — 61.91; 72.59; 71.17; 85.99 score on a scale