N/A N=50 Effects of Deployment Exposures on Cardiopulmonary and Autonomic Function
Abnormality, Respiratory System · Autonomic Nervous System
Primary: FEV1 — 0.94; 1.08; 0.95; 1.09 percentage of predicted normal values
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=268 Work Should Not Hurt You: Reduction of Hazardous Exposures in Small Businesses Through a Community Health Worker Intervention
Community Health Aides · Industrial Hygiene · Volatile Organic Compounds
Primary: Change in Volatile Organic Chemical Concentrations From Pre- to Post-Intervention — 2738; 3875; 523; 225 ppb
Phase 2 N=267 Interventions for HIV Negative Men and Women Who Have High-risk Suspected Exposure to HIV
HIV Prevention · HIV Infections
Primary: Retention, Measured as the Number of HIV Exposure Events That Were Retained in Care at the 24 Week Follow-up Visit — 125; 157 HIV Exposure Events — p=<0.05
N/A N=136 The Risk of HIV Acquisition Among Traditional Healers in South Africa
HIV Infections
Primary: Blood Exposure — 1.9; 1.9 Number of Glove Pairs Used Per Razor Bla
N/A N=24 Evaluation of Post-Exposure Sauna Treatment of Firefighters - A Pilot Study
Post-fire Rehabilitation of Firefighters in Sauna
Primary: Urinary Excretion of Hydroxylated PAHs (PAH-OHs) — 10364.2; 40012.1; 6964.1; 22604.3 ng/L — p=0.0000009
N/A N=163 Impacts of Clinician-Mediated Report-Back
Health Knowledge, Attitudes, Practice
Primary: Knowledge Before and After Report-back Intervention. — 0.06; 0.02 Scores on a scale
N/A N=330 PRIDE: Preventing Respiratory Illnesses During Childhood Study
Tobacco Smoke Pollution
Primary: Air Nicotine Levels — 1.17; 0.58; 0.71; 0.51 mg/m^3
N/A N=9 Woodsmoke Particulate + Hypertonic Saline
Airway Inflammation
Primary: Change From Baseline to 4 Hours in Sputum Percent Neutrophils — -0.04; -0.5 percent neutrophils — p=> 0.99
Phase 3 N=36 Exposure Therapy for Chronic PTSD: Efficacy and Mechanisms
Combat Disorders · Posttraumatic Stress Disorder
Primary: Clinician Administered PTSD Scale (Pre & Posttreatment) — 30.0; 53.6 units on a scale
N/A N=401 Real-Life Passive Exposure Assessment of IQOS
Environmental Exposure
Primary: NEQ: (Non-Exposure Event) — 0.03845; 4.159; 5.695; 0.06876 mg/g
N/A N=60 Health Effects of Secondhand Smoke Exposure in Outdoor Smoking Areas in Patients With COPD and Asthma ( TackSHSWP5 )
COPD · Asthma · Second Hand Tobacco Smoke
Primary: Respiratory Rate — 21.66; 21.57 BR/M breathing rate per min
N/A N=543 Virtual Sun Safe Workplaces Ph II (SSW Works)
Skin Cancer · Occupational Exposure
Primary: Change From Baseline Employee Sun Protection Practices at 1 Year — 3.55; 3.30; 3.71; 3.46 score on a scale
N/A N=150 Erythropoietic Protoporphyrias: Studies of the Natural History, Genotype-Phenotype Correlations, and Psychosocial Impact
Erythropoietic Protoporphyria · EPP · X-Linked Protoporphyria
Primary: The Hospital Anxiety and Depression Scale (HADS) — 4.6; 1.9 score on a scale
N/A N=10 Circadian Rhythm Disruption Effects on Smoke Inhalation
Inflammation · Sleep Deprivation · Circadian Rhythm Sleep Disorder, Shift Work Type
Primary: Blood Inflammation — 0.69; 0.79; 2.33; 1.63 pg/mL — p=<0.05
N/A N=838 Prospective Study of Veteran Health in Previously Deployed Soldiers
Combat Disorders
Primary: Non-Specific Physical Symptoms — 5.2; 7.9; 7.7; 7.7 units on a scale
N/A N=102 European Survey: Risk of Cyanide Poisoning in Smoke Inhalation
Smoke Inhalation Patients
Primary: Overall Survival After 24 Hours — 96 participants
N/A N=5 The Impact of Environmental Controls on Mental Health
Neurologic Disorders
Primary: Percentage of Participants Achieving MCID in PROMIS Global10 Score. — 5 Participants
N/A N=38 Assessing Inflammatory and Behavioral Pathways Linking PTSD to Increased Asthma Morbidity in WTC Workers
Asthma · PTSD
Primary: PTSD Checklist for DSM-5 (PCL-5) — 39.2; 36.4; 32.9; 34.3 score on a scale
N/A N=120 Reduced Exposure Study Using the CHTP 1.2 With 5 Days in a Confinement Setting Followed by 85 Days in an Ambulatory Setting.
Smoking
Primary: Concentrations of Monohydroxybutenylmercapturic Acid (MHBMA) — 285.5; 1904 pg/mg creat — p=<0.001
N/A N=33 Exposure-Based Treatment for Undifferentiated Somatic Symptom Disorder
Somatic Symptom Disorder
Primary: Feasibility 1: Distribution of Physical Symptoms — 11.8 score on a scale
N/A N=86 Vanderbilt Pertussis Exposure Study: PEP in Vaccinated Healthcare Workers Following Pertussis Exposure
Pertussis
Primary: Evidence of Pertussis Infection in Each PEP Arm, Defined Using Clinical, Microbiologic, or Serologic Criteria. — 6; 1 participants
N/A N=88 Post-traumatic Stress Disorder (PTSD) Symptoms in Later Life
Post Traumatic Stress Disorder
Primary: The Trauma History Questionnaire (THQ; Green, 1996) — 5.93; 0.76; 3.81; 0.97 score on a scale
N/A N=2,862 The Respiratory Protection Effectiveness Clinical Trial
Influenza · Respiratory Syncytial Viruses · Paramyxoviridae Infections
Primary: Protective Effects of N95 Respirators vs Medical Masks (MM) as Assessed by Number of Influenza A and B Events — 222; 204 number of influenza A and B events
N/A N=160 Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting Followed by 86 Days in an Ambulatory Setting
Smoking
Primary: Concentration of Monohydroxybutenylmercapturic Acid (MHBMA) — 110.96; 882.25; 94.97 pg/mg creat — p=<0.001
Phase 2 N=12 Woodsmoke Particulate + Prednisone
Airway Inflammation
Primary: Change From Baseline to 4 Hours in Sputum Percent Neutrophils — -2.62; 5.45 percent neutrophils — p=0.24
N/A N=2,000 Morbidity, Mortality And Risk Factors of Mpox in HIV Negative High Risk Sexual Health Clinic Attenders and People Living With HIV
Monkeypox · HIV Coinfection
Primary: Severe Mpox Lesions — 6; 2 participants — p=0.097
N/A N=55 Radiation Exposure of ERCP Personnel at Different Standing Locations and Different Patient Positions.
Occupational Radiation Exposure
Primary: Effective Radiation Dose — 0.0307; 0.0192 mSv
N/A N=434 Personalized Mobile Intervention to Reduce Exposure to Endocrine Disrupting Chemicals in Adults of Child-Bearing Age
Endocrine Disrupting Chemicals · Environmental Exposure · Health Literacy
Primary: Changes in Endocrine Disrupting Chemical (EDC) Levels as Measured by the Post-intervention Value Minus the Baseline Value. — 5.83; 18.43; 56.94; 75.30 ng/ml — p=<0.05
Phase 1 N=7 Exposure Therapy for Veterans With PTSD and Panic Attacks (Phase 1)
PTSD · Panic Attacks
Primary: Clinician Administered PTSD Scale (CAPS) — 29.5 units on a scale
N/A N=56 Impacts of a Report-back Training Program
Behavioral Shift (Researcher Willingness to Report-back)
Primary: Beliefs About Report-back, Before and After Training Program — 1.65; 1.91; 4.47; 4.62 Score on a scale