Phase 1 N=70 Inflammatory Markers in Trauma Patient Outcomes
Polytrauma
Primary: Length of Hospital Stay — 7; 8 days — p==0.275
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Early Phase 1 N=13 Non-Opioid Pramipexole and Pain
Chronic Pain
Primary: Brief Pain Inventory Score — 8; 6.7 score on a scale
N/A N=34 Inflammation and Insulin Resistance in Rheumatoid Arthritis
Rheumatoid Arthritis
Primary: Disease Activity Score Based on 28-joint Disease Activity Score (DAS28) — 4.40; 4.03; 4.57; 4.48 units on a scale
Phase 2 N=60 Evaluating the Role of Neuroinflammation in Low Back Pain
Low Back Pain · Back Pain With Radiation · Back Pain Without Radiation
Primary: Changes in Thalamic Standardized Uptake Value Ratio (SUVR) — 1.188; 1.166; 1.189; 1.165 Standardized uptake value ratio — p=0.956
N/A N=34 Pain Inflammation and Cannabis in HIV
HIV Infections · Neuropathic Pain · Cannabis
Primary: Change in Pain Severity Score — 6.44; 6.86; 8; 7.37 score on a scale — p=0.0303
N/A N=10 Evaluation of Propranolol's Effect on Pain and Inflammation.
Pain Measurement
Primary: Change From Baseline in Heat Pain Threshold During Infusion in Non-Inflamed Skin — 1.01; 0.14; 0.01 degree centigrade
Phase 2 N=101 Evaluation of Inflammation and Pain Post Injection of Ranibizumab vs Aflibercept in Patients With DME
Diabetic Macular Edema
Primary: Number of Participants With Intraocular Inflammation — 6; 10 Participants
Phase 4 N=30 OTC Naproxen and Acetaminophen Anti-Inflammatory Action in Dental Implant Patients
Osseointegrated Dental Implantation · Pain, Acute
Primary: Pain Intensity Scores on Numeric Pain Intensity Scale 0-6 Hours — 1; 3 score on a scale — p=<0.05
Phase 4 N=16 Treatment Of Knee Osteoarthritis With Intra-Articular Infliximab
Osteoarthritis of the Knee
Primary: Change in Cellular Infiltrates From Day 0 to Day 28 — 2; 0; 2; 4 Participants
N/A N=25,871 Vitamin D and Fish Oil for Autoimmune Disease, Inflammation and Knee Pain
Autoimmune Diseases · Systemic Inflammatory Process · Knee Pain Chronic
Primary: Serum Levels of Biomarkers of Systemic Inflammation: Interleukin-6 (IL-6) — 1.71; 1.68; 1.69; 1.70 pg/ml — p=0.02
Phase 4 N=31 Pain Outcomes Following Intralesional Corticosteroid Injections
Keloid · Alopecia Areata · Acne
Primary: Pain Outcome: Visual Analog Scale — 5.4; 2.7 Score on a scale
Early Phase 1 N=144 Inflammation and Daily Life Study
Inflammation
Primary: Loneliness — 47.9; 46.9; 46.8; 44.6 score on a scale
N/A N=20 Acupuncture for Reduction of Inflammation
Thyroid or Parathyroid Surgery
Primary: Reduced Pain Medication Requirement — 5.43; 7.36 mg of Morphine
Phase 4 N=55 Effect IV Ibuprofen and Inflammatory Responses
Gallbladder Disease
Primary: Stress Response Inflammation Markers :Cortisol and C Reactive Protein (CRP) — 173.6; 289.5; 17; 17 pg/mL
Phase 4 N=120 Osteoarthritis Knee Pain Relief Study of 0.25% 920-CGS-200
Osteoarthritis, Knee
Primary: Percentage of Subjects With 50% or Greater Pain Score Reduction From Baseline to 24 Hours After First Dose of Study Drug Treatment. — 27.03; 20.0; 23.08; 20.0 percentage…
N/A N=119 Exercise and Inflammation in the Elderly
Inflammation · Insulin Sensitivity
Primary: Insulin Sensitivity — 50.2; 40.7; 57.5; 42.3 μmol/kgFFM/min
N/A N=39 Anti-Inflammatory Treatment of Schizophrenia
Schizophrenia
Primary: Change in Persistent Positive Symptoms — 13; 14; 14; 14 units on a scale
Phase 4 N=36 Ictal and Interictal Inflammatory Markers in Migraine
Migraine
Primary: Change in the Total Serum Adiponectin (T-ADP) — -0.96; 0.25; -0.97; 0.29 ug/mL
Phase 2 N=100 Evaluation of Pain and Inflammation After Injection of Lucentis vs Eylea for Treatment of Wet Macular Degeneration
Neovascular Age-Related Macular Degeneration
Primary: Evidence of Anterior Chamber Inflammation — 1; 10; 0; 1 participants
Phase 4 N=20 Anti-CGRP for Inflammation and Pain Modulation in Small Fiber Neuropathy/Fibromyalgia
Trigeminal Neuralgia · Glossopharyngeal Neuralgia
Primary: Change in Pain Score — -0.6224; -1.005; -0.8102; -1.079 score on a scale
Phase 4 N=46 Control of Pain in Intravitreal Injections Using Topical NSAIDs
Intravitreal Injections · IVI
Primary: McGill Pain Questionnaire (SF-MPQ) Scores at Baseline — 0.62; 0.93; 0.53 score on a scale
N/A N=300 Do NSAIDS or Executing Exercise Decrease Local Erythema, Site Swelling & Pain After INoculation
Immune System and Related Disorders
Primary: Level of Pain — .39; .19; .14; .56 units on a scale
Early Phase 1 N=46 Pain Management in Teeth With Reversible Pulpitis
Reversible Pulpitis · Ibuprofen
Primary: Change in Pain Intensity From Baseline (Pre-Operative) to Immediately During the Procedure (Day 0), Measured by the Visual Analogue Scale (VAS) — 5.05; 0.64 score on a…
N/A N=253 Pain Research: Innovative Strategies With Marijuana
Chronic Pain · Chronic Low Back Pain · Cannabis Use
Primary: Pain Interference: Roland Morris Disability Questionnaire (RMDQ) — 8.028; 9.635; 9.034; 6.194 score on a scale
Phase 2 N=29 Low Dose Naltrexone for Chronic Pain From Arthritis
Osteoarthritis · Arthritis, Rheumatoid · Arthritis, Psoriatic
Primary: Brief Pain Inventory - Pain Interference — -23; -22 units on a scale — p=0.90
Phase 4 N=343 PAIN - Postoperative Analgesia INvestigation
Postoperative Pain
Primary: Postoperative Pain as Assessed by a Numeric Pain Scale (NPS) — 5.05; 5.02 units on a scale — p=0.934
N/A N=67 Physical Exercise and Its Impact on Signs of Inflammation in Fibromyalgia
Exercise Therapy · Pain
Primary: Six-minute Walk Test — 37.7; 8.6 meter
N/A N=77 Preoperative Etanercept Before Inguinal Hernia Surgery
Inguinal Hernia · Postoperative Pain
Primary: Numerical Rating Scale Pain Score — 3.3; 3.9 units on a scale
Phase 4 N=74 An Assessment of Chronic Synovial-Based Inflammation and Its Role With Serum Urate Levels.
Gout
Primary: Number and Percentage of Participants With Evidence of Chronic Ongoing Synovial-Based Inflammatory Disease at Baseline. — 63 Participants — p=0.34
N/A N=156 Acute Pain Genomic Study
Osteoarthritis · Postoperative Pain
Primary: NRS-Pain With Movement on POD 2 — 2.83 units on a scale