Phase 3 N=77 Drug Treatment for Pathologic Gambling Disorder
Gambling
Primary: Yale-Brown Obsessive Compulsive Scale for Pathological Gambling (PG-YBOCS) — 16.9; 18.6; 9.7; 12.9 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=29 Memantine Treatment Study of Pathological Gambling
Pathological Gambling
Primary: Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling (PG-YBOCS) — 21.8; 8.9 units on a scale
Phase 2 N=34 Clinical Study to Determine if Ecopipam Can Reduce Urges to Gamble
Pathological Gambling
Primary: Statistically Significant (p<0.05) Decrease From Baseline in Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling — 13.9 YBOCS score
Phase 2 N=43 Milk Thistle in Pathological Gambling
Pathological Gambling · Gambling Disorder
Primary: Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling (PG-YBOCS) — -11.76; -11.86 units on a scale
Phase 2 N=62 D1 and D2 Dopamine Receptors in Gambling and Amphetamine Reinforcement
Pathological Gambling
Primary: Subjective Reinforcement Self-report Scales — 4.8; 4.8; 9.5; 9.3 units on a scale
Phase 4 N=28 Acamprosate in the Treatment of Pathological Gambling
Pathological Gambling
Primary: The Primary Efficacy Measure Was the Yale-Brown Obsessive Compulsive Scale Modified for PG (YBOCS-PG). — -.985 units on a scale — p=0.05
Phase 2 N=9 Investigation of Naltrexone for Pathological Gambling
Pathological Gambling
Primary: Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling (YBOCS-PG) — 16.0; 17.0; 10.0; 4.0 units on a scale
Phase 2 N=28 N-Acetyl Cysteine Plus Behavioral Therapy for Nicotine Dependent Pathological Gamblers
Gambling · Tobacco Use Disorder
Primary: Yale-Brown Obsessive Compulsive Scale Modified for Pathological Gambling Total Score — 23.5; 20.4 units on a scale
Phase 2 N=24 Tolcapone Treatment of Pathological Gambling
Pathological Gambling
Primary: Clinical Global Impression Scale (CGI) — 2.88 units on a scale
N/A N=80 Integrative Couple Treatment for Pathological Gambling
Pathological Gambling
Primary: Gambling Symptom Assessment Scale (G-SAS) — 18.52; 16.66; 6.85; 12.39 score on a scale
N/A N=16 The Context of Gambling Treatment: Towards Creating an Online Service to Reduce Problem Gambling - Part Five
Problem Gambling
Primary: Changes in Gambling Frequency as Measured by Self Reported Frequency on 12 Different Types of Gambling. — -2 score on a scale
N/A N=26 The Effect of Self Stigma Tailored Cognitive Behavioral Therapy on Gambling Disorder
Gambling Addiction · Gambling Disorder · Gambling Disorder Treatment
Primary: Change in Self-Stigmatization Score as Measured by the Self-Stigma Scale (SSS). Baseline (Week 0) to Post-treatment (Week 4) and Follow-up (Week 8) — 82.77; 110.3…
N/A N=60 A Psychotherapy Development Study for Internet Gaming
Internet Gaming Disorder
Primary: Percentage of Participants Who Completed All 6 Sessions — 40.6 percentage of participants
N/A N=19 Dopamine Responsivity in Gamblers
Pathological Gambling
Primary: Correlation Between the Impulsive Choice Ratio and Baseline Impulsivity, as Measured With the Barratt Impulsiveness Scale, Non-planning Subscale — -0.5 Correlation…
N/A N=36 Reducing Internet Gaming
Internet Gaming Disorder
Primary: Percentage of Participants Who Complete All 6 Sessions — 78.9 percentage of participants
N/A N=59 Testing Resources: Manual and Webinar Guided Treatment vs. Manual Guided Treatment
Pathological Gambling
Primary: Perceived Stress Scale — 15.2; 14.5 units on a scale
Phase 2 N=10 Memantine Treatment of Compulsive Buying
Compulsive Buying
Primary: Yale Brown Obsessive Compulsive Scale Modified for CB (CB-YBOCS) — 22 units on a scale
N/A N=245 QuitBet Phase II: A Digital Social Game That Pays You to Stop Smoking
Smoking Cessation
Primary: Number of Participants Who Reported no Cigarette Smoking During the Past 7 Days — 30; 35 Participants
Phase 2 N=7 Double-Blind Naltrexone in Compulsive Sexual Behavior
Compulsive Sexual Behavior
Primary: Yale Brown Obsessive Compulsive Scale Modified for Compulsive Sexual Behavior (YBOCS) — 8; 9.33 units on a scale
Phase 2 N=66 N-Acetyl Cysteine in Pathologic Skin Picking
Pathologic Skin Picking · Neurotic Excoriation · Psychogenic Excoriation
Primary: Yale Brown Obsessive Compulsive Scale (YBOCS) Modified for PSP (NE-YBOCS) — 18.8; 17.6; 16.1; 17.3 units on a scale
Phase 3 N=40 Glutamatergic Modulation of Disordered Alcohol Use
Alcohol Dependence
Primary: Percentage of Participants Demonstrating Alcohol Abstinence in the Control (Midazolam) Group Versus the Active (Ketamine) Group — 68.6; 98.6 percentage of participants
Phase 4 N=50 Naltrexone for Impulse Control Disorders in Parkinson's Disease
Impulse Control Disorder · Parkinson Disease
Primary: Percentage of Participants Assessed as Very Much Improved or Much Improved Based on the Clinical Global Impression-Improvement (CGI-I) Scale — 54.4; 33.1 percentage of…
N/A N=300 Psychopathology, Disordered Eating, and Impulsivity as Predictors of Outcomes of Bariatric Surgery
Obesity
Primary: Percent Weight Change — 23.0; 26.2; 23.3 percent weight change
Phase 2 N=18 The Effect of Glutamatergic Modulation on Cocaine Self-administration
Cocaine Dependence
Primary: Number of Choices to Self-administer Cocaine (Out of 5 Choices) — 1.61; 4.33 number of cocaine choices
Phase 2 N=71 Functional Neuroimaging of Alcoholism Vulnerability (PIT)
Healthy
Primary: Change in Blood Oxygenation Level Dependent (BOLD) Activation in the Amygdala During "Win" Monetary Incentive Delay (MID) Task Between Placebo and Study Medication…
N/A N=45 Positive Processes and Transition to Health
Major Depressive Disorder · Post Traumatic Stress Disorder
Primary: Affective Updating Task (Pe et al., 2013; Pe, Raes, et al., 2013) — 0.54 units on a scale
Phase 2 N=25 Double-Blind Naltrexone in Kleptomania
Kleptomania
Primary: Yale Brown Obsessive Compulsive Scale Modified for Kleptomania (K-YBOCS) — 3.83; 11.46 units on a scale
Phase 2 N=12 Memantine in the Treatment of Kleptomania
Kleptomania
Primary: Yale Brown Obsessive Compulsive Scale Modified for Kleptomania (KM-YBOCS) — 5.4 units on a scale
N/A N=62 A Digital Intervention to Improve Physical Activity and Sleep Behaviors in Youth With Psychiatric Diagnoses
Psychiatric Diagnosis
Primary: Feasibility of the App — 88 percentage of visits completed