N/A N=364 Development of an Evaluation Method of Elderly Condition in Patient Receiving Chemotherapy Treatment
Lymphoma · Digestive System Diseases · Ovarian Diseases
Primary: Number of Participant Deaths — 56 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=102 Cardiac Resynchronization in the Elderly
Heart Failure
Primary: Enrollment — 22; 20; 18; 42 Participants
Phase 3 N=1,053 Ezetimibe and Atorvastatin vs. Atorvastatin in Patients Age 65 and Older at High Risk for Coronary Heart Disease (CHD)(0653-112)
Hypercholesterolemia
Primary: Percent Change From Baseline in LDL-C at Week 6 — -26.7; -12.8 Percent Change — p=<0.001
N/A N=346 Expectations and Priorities of Elderly Patients for a First Medical Treatment for Cancer
Breast Cancer · Colorectal Cancer · Kidney Cancer
Primary: Priorities of Patients Receiving First Medical Treatment for Cancer at Treatment Initiation — 199; 93; 141; 80 Participants
N/A N=1,606 Emergency Medicine Palliative Care Access
Advanced Cancer · End Stage Organ Failure
Primary: Change in Quality of Life for Patients, as Measured by the Functional Assessment of Cancer Therapy - General (FACT-G) — 3.7; 3.1 score on a scale
N/A N=264 Patient Priority Care for Older Adults With Multiple Chronic Conditions
Multiple Chronic Conditions
Primary: Treatment Burden — 11.9; 11.6; 12.7; 17.9 score on a scale
N/A N=113,035 Alteplase in Elderly Acute Ischemic Stroke (AIS) Patients During Hospitalization
Stroke
Primary: All-cause Mortality During Hospitalization of Acute Ischemic Stroke (AIS) Patients — 2.6; 0.8 Percentage of participants
N/A N=344 Multiple Chronic Conditions for Older Adults
Chronic Disease
Primary: PROMIS Global Health Measure Score — 46.27; 46.21; 44.92; 46.38 T-score
N/A N=546 Improving Communication in Older Cancer Patients and Their Caregivers
Adult Solid Neoplasm · Lymphoma
Primary: Direct Communication About Age-related Concerns: Number of Discussions Related to the Geriatric Assessment That Occur in the Clinic Visit Between the Patient, Oncology…
Phase 4 N=49 Satisfaction of Treatment Among Elderly Patients With Insulin Therapy
Diabetes Mellitus
Primary: Diabetes Treatment Satisfaction Questionnaire: Status (DTSQs) Score — 28.2; 31.5; 32.2; 34.2 units on a scale
N/A N=178 Patient Priorities Care Among Persons Living With Mild Cognitive Impairment and Dementia
Dementia · Mild Cognitive Impairment
Primary: Documentation of PPC Discussion — 72; 106 Participants
N/A N=1,377 The Effects of Ageing on the 'Pharmacokinetic and Clinical Observations in People Over Fifty'
HIV Positive · Ageing
Primary: The Prevalence of Reported Aches and Pains in the Last Month Across the 3 Age Groups — 473; 224; 188 participants
Phase 2 N=124 Dose-ranging Safety and Tolerability Study in Subjects ≥60 Years of Age
Alzheimer's Disease
Primary: Number of Subjects With Non-serious and Serious Adverse Events (AEs) and Deaths — 18; 19; 22; 20 Participants
N/A N=536 Promoting Informed Decisions About Cancer Screening in Older Adults
Colorectal Cancer Screening
Primary: Shared Decision Making Process (SDMP) Scale Score — 1.1; 1.5 Score on a scale — p=.011
Phase 2 N=69 Efficacy and Tolerance Evaluation in FOLFIRINOX Dose Adjusted in Elderly Patients With a Metastatic Pancreatic Cancer
Pancreatic Metastatic Cancer · Toxicity
Primary: Composite Safety and Early Efficacy Assessment in the First 34 Patients — 65.8 pourcentage of participants
Phase 3 N=205 Telemonitoring Versus Usual Care
Health Care Quality · Health Care Access
Primary: Mean # Participants Who Had Hospitalizations or ED Visits Compared to Usual Care in a High Risk Group of Adults ≥ 60 Years of Age With Mixed Chronic Disease. — 65; 59…
Phase 4 N=67 Using the SEDLine for the Titration of Sevoflurane in Elderly Patients Recovery Using the SEDLine TM for the Titration of Sevoflurane in Elderly Patients Undergoing Non-Cardiac Surgery After Beta-Adrenergic Blockade
Anesthesia, General
Primary: Time to Extubation — 13.0; 12.5 minutes
N/A N=160 Patient-Centered Care for the Older Adult With Hematologic Malignancy
Hematologic Malignancy
Primary: Overall Survival — 79; 49 Participants
Phase 2 N=73 Geriatric Assessment & Genetic Profiling to Personalize Therapy in Older Adults With Acute Myeloid Leukemia
Adult Acute Myeloid Leukemia · Secondary Acute Myeloid Leukemia · Therapy-Related Acute Myeloid Leukemia
Primary: Rate of Complete Remission and Mortality in the Entire Cohort of Older Patients — 21.9; 52.0 percentage of subjects
N/A N=372 A Randomized Controlled Trial to Deprescribe for Older Patients With Polypharmacy
Polypharmacy · Care Transitions · Geriatric Syndromes
Primary: Total Number of Medications — 15; 16; 13; 15 Medications — p=0.017
N/A N=1,560 Alteplase Treatment in Elderly Acute Ischaemic Stroke (AIS) Patients
Stroke
Primary: Percentage of Patients With Favourable Outcome (Modified Rankin Scale (mRS) 0-1) at 1 Year — 27.7; 23.8 Percentage of Participants — p=<0.001
N/A N=1,552 Study Of Telemedicine Consultation at Home For Older Adults
Physical Disorders · Telemedicine
Primary: Emergency Department Use — 0.1050; 0.0885 Emergency dept use rate per person-month — p=0.017
N/A N=14,442 A Program to Reduce Inappropriate Medications Among Older Adults With Alzheimer's Disease
Alzheimer Disease
Primary: Time to Dispensing of Inappropriate Medication Prescription — 76.7; 77.9; 77.5 Percentage of Cumulative Incidence — p=0.76
Phase 2 N=83 Pembrolizumab in Elderly Patients With Advanced Lung Cancer
Non Small Cell Lung Cancer
Primary: Overall Survival — 19.2 Months
Phase 4 N=361 Study on the Treatment of Elderly Patients With Older and Newer Antiepileptic Drugs
Focal Epilepsy
Primary: 58-week Retention Rate Measured by the Number of Drop Outs Due to Adverse Events or Seizures From Day 1 of Treatment — 0.61; 0.46; 0.56 proportion of participants…
Phase 3 N=302 Enhancing Fitness in Older Pre-diabetic Veterans
Impaired Glucose Tolerance · Obesity · Diabetes
Primary: Fasting Insulin — 10.26; 10.39 uIU/ml
N/A N=22 Compassion Meditation for Older Adults
Anxiety and Mood Disorders
Primary: Enrollment Rate — 25; 0 Participants
N/A N=102 Shared Decision Making in Dialysis
End Stage Renal Disease · Chronic Kidney Diseases
Primary: Mean Feasibility of Intervention Measure — 16.4; 16.1; 19.0 score on a scale
N/A N=91 The Impact of Sharing Audio Recorded Clinic Visits on Self-management in Older Adults
Diabetes Mellitus · Hypertension
Primary: Participant Retention (Feasibility) — 44; 45 Participants
N/A N=229 Enhanced Medical Rehabilitation in Older Adults
Disabling Medical Events · Disabled · Depression
Primary: Change in Barthel Index Score — 28.48; 34.92 score on a scale — p=0.007