Phase 4 N=52 Regional Anesthesia Following Pediatric Cardiac Surgery
Atrial Septal Defect · Ventricular Septal Defect · Pain, Procedural
Primary: Total Amount of Opioid Medications Administered — 0.44; 0.83 MME/kg — p=0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=72 Positive Pressure at Induction of Anesthesia in Children
Continuous Positive Airway Pressure · Hypoxia · General Anesthesia
Primary: Time Between Onset of Apnea and the Drop in 95% Oxyhemoglobin Saturation Levels — 227.65; 133.68 seconds — p=<0.0001
N/A N=23 Changes in Tissue and Cerebral Oxygenation Following Spinal Anesthesia in Neonates, Infants, and Children
Infants Undergoing Surgery
Primary: Cerebral Non-invasive Near Infrared Spectroscopy (NIRS) — 0.05 percentage change per minute
N/A N=89 The Effect of Anesthesia on Neurodevelopmental Outcome (NDO)
Anesthesia; Adverse Effect · Congenital Heart Disease · Neurodevelopmental Disorders
Primary: Bayley III — 91; 93; 88; 90 score on a scale
N/A N=660 Success of Pediatric Anesthesiologists in Learning to Use Videolaryngoscopes
Tracheal Intubation Morbidity
Primary: Success in Learning to Use a Videolaryngoscope(VLS) — 37.5; 62.5; 25; 0 percent of anesthesiologists — p=>0.05
Phase 4 N=61 Methadone in Pediatric Anesthesia
Anesthesia
Primary: R-methadone Plasma AUC 0-96hr/Dose — 228; 189; 205; 0 (ng * hr-1 * ml-1 * mg-1 — p=<0.05
N/A N=117 Cartoon Distraction and Parental Presence on Anxiety in Pediatric Anesthesia
Anxiety, Separation · Psychomotor Agitation
Primary: Modified Yale Preoperative Anxiety Scale Scores at Baseline, Arrival in Operating Room, and Inhalation Induction — 28.4; 28.4; 23.4; 23.4 units on a scale
Phase 3 N=80 Propofol in Obese Children
Pharmacodynamics · Obesity
Primary: Dose of Propofol That Caused Loss of Consciousness in 95% (ED95) of Obese and Non-obese Children — 2; 2.125 mg/kg
Phase 4 N=102 Propofol for Pediatric Tracheal Intubation With Deep Anesthesia During Sevoflurane Induction
Anesthesia Intubation Complication
Primary: Estimated Propofol Doses Producing 50% Excellent Intubation Conditions — 1.48; 0.00; 0.07; 2.35 mg/kg
N/A N=179 Comparing Anesthetic Techniques in Children Having Esophagogastroduodenoscopies
Eosinophilic Esophagitis
Primary: Number of Participants With Respiratory Complications — 0; 0; 15; 0 Participants — p=<0.0001
Phase 4 N=20 Awake Caudal Catheter vs General Anesthesia
Inguinal Hernia
Primary: Number of Participants With Return to Baseline Respiratory Function. — 11; 9 Participants
N/A N=482 The Use of Apneic Oxygenation During Prolonged Intubation in Pediatric Patients: a Randomized Clinical Trial
Intubation of Pediatric Dental Surgery Patients
Primary: Time of Oxygen Saturation Change — 30; 67; 75 seconds
N/A N=234 Dysrhythmias During General Anesthesia in Children
Arrhythmias, Cardiac
Primary: Arrhythmias During General Anesthesia in Children — 220 participants
N/A N=120 Pediatric Temperature Variation in the MRI Scanner Under General Anesthesia
Children Requiring MRI
Primary: Change in Body Temperature in Children Undergoing MRI Under General Anesthesia (GA)and Change in Room Temperature Before and After MRI — 36.7; 36.3; -0.4; 21.1 celsius…
N/A N=170 Bispectral Index and End-Tidal Anesthetic Gas Concentration in Pediatric Patients
Anesthesia
Primary: End-tidal Sevoflurane Concentration — 2.1; 1.8; 2.5; 2.1 percent sevoflurane
Phase 4 N=643 A Multi-site Randomized Controlled Trial Comparing Regional and General Anesthesia for Effects on Neurodevelopmental Outcome and Apnea in Infants
Inguinal Hernia
Primary: Full Scale IQ Score — 100.5; 100.1 score on scale
Phase 2 N=30 Stress Response and Neurodevelopmental Outcome After Cardiac Surgery Utilizing CPB in Children: A Prospective, Double Blinded and Randomized Study
Congenital Heart Disease
Primary: Change in Cytokine Levels — 4.38; 4.2; 3.98; 3.85 picograms per milliliter
N/A N=178 Audiovisual Interactive Games to Alleviate Pediatric Perioperative Anxiety
Anxiety
Primary: Patient Anxiety Assessed by Modified Yale Perioperative Anxiety Score (mYPAS) — 5; 21.4; 0.18; 8.9 score on a scale — p=<0.001
N/A N=360 Apneic Oxygenation During Airway Management in Pediatric Patients
Hypoxia
Primary: Time to First Event: Pulse Oximetry at 95%, or Successful Intubation — 106; 169 seconds
N/A N=71 Perioperative Virtual Reality for Pediatric Anesthesia
Anxiety
Primary: Perioperative Pediatric Anxiety (Change From Baseline) — 0.0; 5.0 units on a scale
N/A N=40 The Effect of Depth of Anesthesia as Measured by Bispectral Index (BIS) on Emergence Agitation in Children
Emergence Agitation
Primary: Peak Pediatric Assessment of Emergence Delirium (PAED) Score Within the First 30 Minutes of Reaching the Recovery Room (Post-Anesthesia Care Unit) — 8.6; 6.7 units on a…
N/A N=50 Performance Evaluation of the Depth of Anesthesia Monitors in Pediatric Surgery
Anesthesia · Child
Primary: BISPECTRAL Index — 0.6; 0.66; 0.73 units on a scale — p=<0.01
N/A N=30 Anesthesia During Neurophysiologic Monitoring in Scoliosis Patients
Idiopathic Scoliosis
Primary: Amplitude Required to Elicit the MEP — 307; 417 milliamperes
Early Phase 1 N=143 Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery
Emergence Agitation · Pain
Primary: Emergence Agitation (EA) as Measured by Standardized PAED Scale — 5.3; 4.99; 6.29 score on a scale
N/A N=114 Relationship Between Preoperative Anxiety, Postoperative Pain, and Emergence Delirium in Pediatric Surgery
Postoperative Pain · Preoperative Anxiety · Emergence Delirium in Pediatric Anesthesia
Primary: Postoperative Pain Intensity — 1; 1; 3; 1 score
N/A N=211 Detecting Post-Operative Respiratory Depression in Children
Respiratory Depression
Primary: Abnormal ETCO2 Values, Abnormal Pulse Oximetry Values, and Staff Interventions — 56; 58; 8; 15 participants
Phase 4 N=34 Peri-operative Use of a Pain Injection in Pediatric Patients With Cerebral Palsy
Cerebral Palsy · Hip Dysplasia · Pain, Postoperative
Primary: Opioid Consumption — 0.41; 1.87 mEQ/kg
N/A N=40 Closed Loop Propofol Administration in Pediatric Cardiac Surgery
Pediatric Cardiac Surgery · Intraoperative Awareness · Automated Drug Delivery
Primary: Percentage of Time Bispectral Index(BIS) Remains+/-10 of Target — 77.4; 75 percentage of time
N/A N=51 Methadone in Pediatric Anesthesiology II
Pain
Primary: Total Opioid Consumption (Morphine Equivalent) — 2.22; 2.37; 3.28 mg/kg — p=.002
Phase 2 N=200 Recovery After Total Intravenous Anesthesia With Ketofol Versus Mixture of Ketofol and Lidocaine for Short Pediatric Surgery
Surgical Procedure, Unspecified
Primary: Effect of TIVA With Ketofol and Ketofol Plus Lidocaine on Extubation Time in Children — 240; 120 second