Phase 2 N=32 Gulf War Illness: Evaluation of an Innovative Detoxification Program
Gulf War Illness
Primary: Short Form-36 for Veterans Quality of Life Physical Component Summary Scores — 30.3; 36.7; 38.2; 35.7 score on a scale — p=<0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=54 Gulf War Digestive Health Study
Irritable Bowel Syndrome · Small Intestinal Bacterial Overgrowth
Primary: Global Improvement Scale — 4.3; 4.3 units on a scale — p=0.26
Phase 2 N=83 Gulf War Illness Inflammation Reduction Trial
Chronic Inflammation · Chronic Pain · Fatigue
Primary: Change From Baseline of Veterans RAND 36-Item Health Survey Physical Component Summary Score (PCS) Scores at 8 and 16 Weeks — 40.8; 41.5; 43.5; 43.4 units on a scale
Phase 2 N=170 Complementary Neurosteroid Intervention in Gulf War Illnesses (GWVI)
Fatigue · Musculoskeletal Pain · Cognitive Decline
Primary: Physical Component of the SF-36 — 2.04; 2.55; 1.23; 4.45 score on a scale
N/A N=268 Cognitive Rehabilitation for Gulf War Illness
Gulf War Illness
Primary: Disability - WHO-DAS 2 Change — -2.81; -2.21 score on a scale — p=0.712
N/A N=838 Prospective Study of Veteran Health in Previously Deployed Soldiers
Combat Disorders
Primary: Non-Specific Physical Symptoms — 5.2; 7.9; 7.7; 7.7 units on a scale
N/A N=55 Mindfulness-Based Stress Reduction for Gulf War Syndrome
Persian Gulf Syndrome
Primary: The Short-form McGill Pain Questionnaire — 54.0; 65.5 units on a scale
N/A N=29 Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment
Apnea, Sleep · Chronic Fatigue Syndrome
Primary: Change of Fatigue Symptom — 2.1; 0.2 units on a scale — p=0.0002
Phase 2 N=40 Gulf War Illness Nasal Irrigation Study
Persian Gulf Syndrome · Chronic Sinusitis · Fatigue
Primary: Change in Sino-Nasal Outcome Test (SNOT-20) Score From Baseline — -16.9; -8.8; -3.4; -18.9 score on a scale
Phase 2 N=104 Acupuncture in the Treatment of Gulf War Illness
Persian Gulf Syndrome
Primary: SF-36P — 73.7; 64.3 units on a scale — p=0.03
N/A N=27 Vagus Nerve Stimulation: Treatment for Gulf Veterans With Gulf War Illness
Pain · Migraine
Primary: Visual Analog Scale (VAS) to Assess Change of Widespread Pain — 4.70; 5.40; 5.43; 3.56 Units on a scale — p=0.47
N/A N=75 Treating Chronic Pain in Gulf War Illness
Chronic Pain · Gulf War Illness · Chronic Illness
Primary: Pain (Brief Pain Inventory - Short Form) - Pain Severity — -.87; -.24 units on a scale — p=.25
N/A N=54 Impact of Exercise Training on Pain and Brain Function in Gulf War Veterans
Chronic Musculoskeletal Pain
Primary: Short Form McGill Pain Questionnaire Visual Analog Scale (VAS). — 29.82; 37.08; 30.07; 31.46 units on a scale — p=0.680
N/A N=21 Management of Chronic Pain and PTSD in Gulf War Veterans With tDCS+Prolonged Exposure
Chronic Pain · PTSD
Primary: Feasibility of Recruitment as Assessed by Number of Participants Enrolled in the Study — 21 Participants
N/A N=50 Effects of Deployment Exposures on Cardiopulmonary and Autonomic Function
Abnormality, Respiratory System · Autonomic Nervous System
Primary: FEV1 — 0.94; 1.08; 0.95; 1.09 percentage of predicted normal values
Phase 3 N=100 Coenzyme Q10 Phase III Trial in Gulf War Illness
Gulf War Illness · Chronic Fatigue · Ubiquinol
Primary: Veterans Short Form 36-Item Health Survey Physical Component Summary — 1.6; -1.1; 1.4; 1.1 units on a scale
N/A N=96 Effects of Botanical Microglia Modulators in Gulf War Illness
Gulf War Illness
Primary: Change From Baseline in Overall Gulf War Illness Disease Severity — 13; 0; 8; -1 units on a scale
N/A N=85 Cognitive Behavioral Therapy for Insomnia for Gulf War Illness
Gulf War Illness · Insomnia
Primary: Gulf War Illness Symptom Severity Index — 67; 67; 61; 49 score on a scale — p=<0.01
N/A N=149 CAM in Veterans With Gulf War Illnesses
Gulf War Veterans' Illness
Primary: Veterans RAND 36-item Health Survey - Mental Component Summary Scale — 42.26; 41.75; 44.48; 40.62 score on a scale
N/A N=49 Assessing Neuroinflammation in GWI Using MRS
Gulf War Syndrome
Primary: Concentration of Myoinositol in the Brain — 0.001260; 0.001205 Institutional Units (IU)
N/A N=114 Novel Interventions for GWVI
Gulf War Veteran's Illness
Primary: Change in Brief Pain Inventory - Short Form (BPI) - Pain Interference — 4.47; 4.77; 3.59; 3.66 score on a scale — p=0.58
Phase 2 N=33 Treatment Study of Carnosine Versus Placebo in Gulf War Illness (GWI)
Persian Gulf Syndrome
Primary: Effect of Carnosine Supplementation on Chronic Fatigue Syndrome Severity Scores — -3.8; -2.0 units on a scale — p=0.30
N/A N=1,242 Service and Health During the Iraq and Afghanistan Era
Iraq and Afghanistan Era Veterans
Primary: Participation Rates — 137; 121; 14 Participants
N/A N=20 Glutathione and Health With Post-Polio Syndrome
Post-polio Syndrome · Physical Activity · Depression
Primary: PROMIS (Patient Reported Outcomes Measurement Information System) Physical Functioning — 37.8; 37.9; 37.5; 38.1 units on a scale — p=0.66
N/A N=314 Primary Immunodeficiency in Kuwait
Primary Immune Deficiency Disorder
Primary: Number of Participants With Different Epidemiological Features — 287; 100; 68; 56 patients
N/A N=50 Predictors of Response to Insomnia Treatments for Gulf War Veterans
Insomnia
Primary: Insomnia Severity Index (ISI) — 17.0; 18.9; 7.3; 10.9 score on a scale