N/A N=23 Treating Phobia With Multivoxel Neuro-reinforcement
Phobia
Primary: Change in Amygdala Reactivity — -.691; -.827; -.278 Beta Coefficient
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=48 Attention Disengagement Training for Social Phobia
Social Anxiety Disorder
Primary: Liebowitz Social Anxiety Scale (LSAS) — 68.1; 74.5; 60.0; 46.1 units on a scale
N/A N=606 Stress, Sex, and the Generalization of Fear
Psychological Stress
Primary: Fear-potentiated Startle Responses to the CS+ and CS- During Acquisition — 52.059; 19.162; 44.388; 9.732 Fear-potentiated startle (microvolts) — p=0.453
N/A N=918 Expectation of Unpleasant Events in Anxiety Disorders
Anxiety Disorders
Primary: Change in Percent of Correct Button Presses During Threat Compared to the Safe Condition (AAST) — -0.016; 0.008 Percentage of accurate responses
N/A N=49 Interpretation Modification Program for Social Phobia
Social Anxiety Disorder · Social Phobia
Primary: Liebowitz Social Anxiety Scale (LSAS) — 82.0; 77.7; 50.2; 67.6 units on a scale
N/A N=37 A Unified Treatment for Anxiety Disorders
Emotional Disorders · Anxiety Disorders
Primary: Anxiety Disorders Interview Schedule for DSM-IV — 5.23; 5.09; 3.18; 5.14 score on a scale
N/A N=106 Assessment and Treatment of Social Skills Deficits in Individuals With Social Phobia
Social Phobia
Primary: Social Phobia Remission
Phase 4 N=172 Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders
Posttraumatic Stress Disorder · Anxiety Disorder
Primary: Change From Baseline Skin Conductance Response — .06; .17; -1.27; -.04 microSiemens — p=>.05
N/A N=54 Telemedicine-Based Virtual Reality Clinic for the Treatment of Phobias
Arachnophobia · Cynophobia · Ophidiophobia
Primary: Phobia Symptom Severity — 2.80; 3.18; 1.51; 1.55 units on a scale
Phase 2 N=54 fMRI Study Examining Effects of D-cycloserine in Specific Phobia
Phobias
Primary: fMRI Brain Activations During Symptom Provocation — .200; .157; -.013; .036 percent signal change
Phase 2 N=33 Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Primary: Pediatric Anxiety Rating Scale. — 11.62; 14.04 units on a scale — p=.04
Phase 4 N=169 D-Cycloserine Enhancement of Exposure in Social Phobia
Social Anxiety Disorder
Primary: Liebowitz Social Anxiety Scale (LSAS) — 39.19; 42.44 units on a scale
N/A N=136 Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder
Obsessive-Compulsive Disorder in Children · Social Anxiety Disorder of Childhood · Obsessive-Compulsive Disorder in Adolescence
Primary: Pediatric Anxiety Rating Scale — 10.86; 10.96 score on a scale
N/A N=136 Effectiveness of a Family-Based Treatment for Preventing Anxiety Disorders in At-Risk Children
Anxiety Disorders
Primary: Anxiety Disorders Interview Schedule for Diagnostic and Statistical Manual for Psychological Disorders-IV, Child and Parent Versions (C/P-ADIS) — 19; 3 participants with…
Phase 3 N=45 Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Autism · Asperger's Syndrome · Generalized Anxiety Disorder
Primary: Pediatric Anxiety Rating Scale (Measures the Severity of Anxiety Symptoms) — 16.33; 17.62; 11.58; 16.05 units on a scale
N/A N=99 Fear, Gastrointestinal Distress, and Interoception: Physiological and Psychological Mechanisms in Eating Disorders
Feeding and Eating Disorders
Primary: Subjective Rating of Fear — -36.9444; -23.9219; -47.3611; 85.6250 units on scale*minutes — p=.879
Phase 2 N=41 PH94B in the Treatment of Adjustment Disorder With Anxiety
Adjustment Disorder With Anxious Mood
Primary: Hamilton Anxiety Scale (HAM-A) Score — -12.5; -12.6 score on a scale — p=0.9338
N/A N=167 Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Autism Spectrum Disorders · Autism · Asperger's Syndrome
Primary: Change From Baseline in Anxiety Severity on the Pediatric Anxiety Rating Scale After 16 Weeks of Treatment. — 3.43; 3.47; 3.28; 2.13 units on a scale
Phase 3 N=201 Comparison of Psychotherapy Programs to Treat Panic Disorder
Anxiety Disorders · Panic Disorder · Agoraphobia
Primary: Panic Disorder Severity Scale — 6.72; 5.78; 7 score on a scale — p=>0.16
N/A N=20 Exposure, D-cycloserine Enhancement, and Functional Magnetic Resonance Imaging (fMRI) in Snake Phobics
Specific Phobia
Primary: Snake Questionnaire (SNAQ) — 9.6; 9.7 units on a scale
N/A N=90 Treatment of Social Anxiety Disorder and Selective Mutism
Social Anxiety Disorder · Selective Mutism
Primary: Change in Clinical Severity Ratings (CSR) of SAD & SM on the Anxiety Disorders Interview Schedule - Parent Version (ADIS-P) — -1.26; -1.65; -1.51; -1.24 units on a scale…
N/A N=40 Family-Based Prevention Program for Childhood Anxiety
Anxiety Disorders
Primary: Number of Children With Child Anxiety Diagnosis — 20; 20 participants
Phase 3 N=29 D-Cycloserine to Enhance Cognitive Behavioral Therapy (CBT) for Acrophobia
Phobic Disorders
Primary: Acrophobia Questionnaire With Avoidance (AAVQ) — 9.00; 12.38 units on a scale
Phase 2 N=83 SPD503 in Subjects Aged 6-17 Years With Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder (SAD), or Social Phobia (SoP)
Generalized Anxiety Disorder (GAD) · Anxiety, Separation · Phobia, Social
Primary: Change From Baseline in Systolic Blood Pressure at Up to 12 Weeks — -1.7; -2.3 mmHg
N/A N=32 Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety
Autism · Asperger's Syndrome · Pervasive Developmental Disorder Not Otherwise Specified
Primary: Pediatric Anxiety Rating Scale — 7.79; 15.06 units on a scale
Phase 4 N=1,004 Primary Care Intervention Strategy for Anxiety Disorders
Post-traumatic Stress Disorder · Generalized Anxiety Disorder · Panic Disorder
Primary: BSI-12 (Anxiety and Somatization Subscales) — 325; 258 number of responders
N/A N=1,063 Brain Imaging Changes in Fear and Anxiety
Anxiety Disorders · Fear
Primary: Average Correlations Between Average Time Series - Left & Right Hemisphere of the Brain — 0.9; 0.92 correlation coefficient (r) — p=< 0.001
N/A N=305 Kids FACE FEARS Comparative Effectiveness Research
Child Anxiety · Anxiety Disorders · Anxiety
Primary: Promis Pediatric Short Form v. 2.0-Anxiety (Parent Proxy/Caregiver Report) — 65.7; 66.0; 59.2; 59.1 T-Score