N/A N=50 Pulmonary Function and Interscalene Block
Shoulder Arthroscopy
Primary: Number of Patients With Paradoxical Diaphragmatic Movement — 16; 8 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=26 Evaluation of Diaphragm Movement After an Interscalene Block
Phrenic Nerve Paralysis
Primary: Diaphragm Excursion With Sigh — 4.2; 2.9 cm
N/A N=54 Electrical Activation of The Diaphragm for Ventilatory Assist
Spinal Cord Injury · Quadriplegia
Primary: Enrolled Subjects Achieve Clinically Acceptable Tidal Volume Sustained Over a Continuous 4 Hour Period. — 52; 1 Participants — p=<0.001
N/A N=6 Diaphragm Pacing in Individuals With Spinal Cord Injuries
Cervical Spinal Cord Injury
Primary: Change in Electromyogram (EMG) — -.0031 mV
N/A N=30 The Effect of Interscalene Peripheral Nerve Block With 0.25% Bupivacaine vs 0.125% Bupivacaine on Lung Function
Diaphragm Paralysis
Primary: Abnormal Lung Function — 11; 3 participants w/ abnormal diaphragm fxn
Phase 4 N=21 Dose-Response Relationships for Hemidiaphragmatic Paresis Following Ultrasound-Guided Supraclavicular Block
Surgery of Right Upper Extremity
Primary: Number of Subjects With Hemidiaphragmatic Paresis at Various Volumes of Local Anesthetic 15 Minutes After Supraclavicular Block — 1; 1; 1; 2 Participants
N/A N=120 Treatment of Critical Illness Polyneuromyopathy
Acute Respiratory Failure
Primary: The Primary Outcome Variable for This Study Will be the Short Form of the Continuous Scale Physical Functional Performance Test (CS-PFP) Called the PFP-10 — 19.0; 20.9…
N/A N=25 Effect of Diaphragm Stimulation During Surgery
Mechanical Ventilation Complication · Diaphragm Injury
Primary: Mitochondrial Respiration — 3.5; 2.9; 31.1; 27.1 pmol/s/mg wwt
N/A N=39 Bupivacaine Versus Ropivacaine on Diaphragmatic Motility and Ventilatory Function
Paresis
Primary: Forced Expiratory Volume at 1 Second (% Change From Baseline) — -22.4; -29.4 percentage of change from baseline
N/A N=10 Feasibility Study for Intrathoracic Nerve Stimulation
Postoperative Pain
Primary: Pain as Measured by the Visual-analog Scale — 1 units on a scale
N/A N=15 Mapping for Acute Transvenous Phrenic Nerve Stimulation Study
Sleep Apnea
Primary: Number of Patients With Response to Stimulation (Diaphragmatic Movement Achieved) — 15 Participants
N/A N=9 Response to Diaphragmatic Pacing in Subjects With Pompe Disease
Pompe Disease
Primary: Off-ventilator Spontaneous Breathing (SB) at Baseline and Day 180 — 0.52; 4.72 hours per day
N/A N=14 Splanchnic Nerve Anesthesia in Heart Failure
Heart Failure
Primary: Central Venous Pressure — 18.73; 14.91 mmHg
N/A N=1 Reanimation in Tetraplegia
Spinal Cord Injury (Quadraplegia)
Primary: Number of Participants With Voluntary Movement — 1; 0 Participants
Phase 4 N=20 Rib Fracture Analgesia Using Cryoanalgesia
Traumatic Rib Fracture(s)
Primary: Maximum Inspired Volume — 2250; 1300 mL
N/A N=53 Electrical Stimulation in Patients With Prolonged Mechanical Ventilation
Respiratory Failure
Primary: Level of Activity of Daily Life — 25.2; 32.0 units on a scale — p=0.652
N/A N=12 Clinical Study to Investigate Safety and Performance of TransLoc Electrodes in Patients Undergoing Surgical Procedures
Diaphragm Pacing
Primary: Number of Participant That Experience Adverse Procedure and/or Device Effects — 0 Events
N/A N=80 Paravertebral Block for Proximal Humeral Fracture Surgery
Proximal Humeral Fracture
Primary: Success Rate(Ability to Proceed With Surgery Without the Need for Intravenous Narcotics, General Anaesthesia, Rescue Blocks or Local Infiltration by the Surgeon) — 31…
Phase 4 N=60 The Use of Paravertebral Block for Cardiac Surgery
Mitral Valve Insufficiency
Primary: Postoperative Fentanyl — 4.51; 6.14 microgram/kilogram
N/A N=42 Replaceability of Fluoroscopy and Ultrasound in the Evaluation of Hemidiaphragm Excursion
Diaphragm Disease
Primary: Diaphragm Function — 4.25 centimeters — p=<0.05
N/A N=6 Sub-study to Spinal Cord Stimulation to Restore Cough
Spinal Cord Injuries · Spinal Cord Diseases · Paralysis
Primary: The Effects of Electrical Spinal Cord Stimulation (SCS) on Airway Pressure Generation While Using Temporarily Placed Parallel Wire Leads and Implanted Disc Electrodes…
Phase 4 N=100 Neuromuscular Blockade on Shoulder Pain of Elderly
Malignant Neoplasms of Digestive Organs · Malignant Neoplasms of Female Genital Organs · Malignant Neoplasms of Male Genital Organs
Primary: Percentage of Patients Who Reported Shoulder Pain — 12; 10 percentage of participants
Phase 2 N=79 Parasternal Nerve Block in Cardiac Patients
Coronary Artery Disease · Pain, Postoperative
Primary: Median Cumulative Morphine Equivalent — 0; 2.5; 0; 5 Morphine Equivalents
Phase 4 N=119 Pectoralis Block vs Paravertebral Nerve Blocks for Breast Surgery
Breast Surgery
Primary: Recovery Room Numeric Rating Scale Pain Scores — 3.3; 1.3 score on a scale
Phase 4 N=42 Effect of Deep Neuromuscular Block (NMB), Inhalation or TIVA on Pneumoperitoneum.
Muscle Relaxation
Primary: Effect of Anesthetics on the Pressure at Zero Volume (PV0) Measured During Insufflation of the Abdomen — 5.7; 8.29; 6.58 mmHg
N/A N=117 Intraoperative Neuromuscular Blockade and Postoperative Atelectasis
Thoracic Surgery · One-lung Ventilation
Primary: Atelectasis Area on Chest CT — 1.32; 1.41 percentage of atelectasis volume
Phase 2 N=19 Abdominal Nerve Blockade in Chronic Heart Failure.
Heart Failure
Primary: Exercise Capacity as Measured by Peak Oxygen Uptake (Peak VO2) — 9.1; 9.8 mL/kg/min — p=0.053
N/A N=48 Comparative Study of Nonintubated Uniport Thoracoscopic Surgery Using Thoracic Paravertebral Nerve Block Versus Intercostal Nerve Block for Peripheral Solitary Pulmonary Nodule Patients
Peripheral Solitary Pulmonary Nodule or Tuberculoma
Primary: Comparing the Inflammatory Markers During the Operation After the Intervention of the Each Group — 33; 35; 39; 42 pg/L — p=0.025
Phase 2 N=57 Chronic Evaluation of Respicardia Therapy
Sleep Disordered Breathing · Cheyne Stokes Respiration · Periodic Breathing
Primary: AHI Change From Baseline at 3 Months — -27.1 events/hour — p=<.001
Phase 4 N=100 Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery
Neuromuscular Blockade · Postoperative Complications
Primary: Number of Participants With Postoperative Pulmonary Complications — 8; 8 Participants — p=1.00