Phase 2 N=23 Effect of a Commercial Cosmetic Mouth Rinse on Plaque Re-growth
Healthy Subjects
Primary: Plaque Index of Test Mouth Rinse Versus Sterile Water After Day 4 of Treatment Administration — 3.03; 3.23 Score on a scale — p=0.0915
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=49 Compare Anti-inflammatory Dentifrices
Gingivitis
Primary: Gingival Index (GI) — 1.04; 1.01 units on a scale — p=<0.05
N/A N=61 Trial of Toothpaste to Reduce Plaque and Inflammation
Plaque · Inflammation
Primary: Change in Oral Plaque — -1.05; -0.03 log(percentage) — p=0.001
Phase 3 N=23 Clinical Study to Evaluate Dental Plaque
Gingival Diseases
Primary: Dental Plaque Index — 2.48; 2.42 Units on a scale — p=0.05
N/A N=56 Ability of Four Toothpastes to Remove Plaque
Dental Plaque
Primary: Mean Change From Baseline (Pre-brushing to Post-brushing) in Turesky Score After Single Supervised Use (Test Product 1 Versus [vs] Test Product 4) After 4 Weeks — 2.90…
Phase 3 N=32 Evaluate Dental Plaque Benefit of a Preventive Treatment Gel
Dental Plaque
Primary: Mean Turesky Modified Quigley-Hein Index at Day 4 — 1.83; 1.96 score on a scale
Phase 3 N=19 Investigation of Dental Plaque and Gingival Index
Dental Plaque
Primary: Gingival Margin Plaque Index — 15.4; 12.81 Units on a scale — p=0.05
Phase 3 N=6 Effect on Bacterial Glycolytic Acid Formation on Plaque
Dental Plaque
Primary: ph of Dental Plaque After Sucrose Challenge — 4.88; 5.04; 4.98 ph of dental plaque — p=0.05
N/A N=32 Induced Gingivitis & Intra-oral Imaging
Plaque Induced Gingivitis
Primary: Change From Baseline Gingivitis at Day 14 as Measured by Non-invasive Microimaging and Gingival Index. — 0.6; 0.15 units on a scale
Phase 3 N=129 Plaque Regression and Progenitor Cell Mobilization With Intensive Lipid Elimination Regimen (PREMIER), Phase II
Acute Coronary Artery Syndrome
Primary: Change in the Total Atheroma Volume From Baseline to 12 Weeks — -7.63; -3.10 mm^3 — p=0.2533
N/A N=90 A Comparative Study of Electric Toothbrushes for the Efficacy Plaque Removal and the Effect on Plaque Accumulation and Gingivitis.
Dental Plaque Induced Gingivitis · Dental Plaque
Primary: Plaque Index — 1.07; 1.19; 1.31; 1.11 units on a scale — p=0.1561
N/A N=60 Platelet Rich Fibrin vs Sub Epithelial Connective Tissue and Coronally Advanced Flap Alone in Gingival Recession
Gingival Recession
Primary: Gingival Thickness — 1.97; 1.95; 1.39 millimeter
N/A N=36 The Use of Platelet Rich Fibrin in Pulpal and Periodontal Regeneration in Mature Teeth
Pulpal Necrosis
Primary: Vitality of Teeth (Units) Using Thermal and Percussion Sensitivity Trend Observed During Study Duration (3-11 Months) — .559; .592; .065; .040 Teeth
N/A N=40 Platelet-rich Fibrin and Connective Tissue Graft in Recession Treatment
Gingival Recession
Primary: Vertical Recession — 3.35; 3.20; 0.38; 0.65 mm — p=0.259
N/A N=80 Efficacy of Manual Toothbrushes in Removing Dental Plaque
Dental Plaque · Oral Hygiene
Primary: Change From Pre to Post Brushing in Overall Mean Rustogi Modified Navy Plaque Index (RPI) After a Single Brushing Event at Day 0 — -0.09623; -0.12005; -0.09859; -0.09599…
Phase 3 N=31 Plaque Regression and Progenitor Cell Mobilization With Intensive Lipid Elimination Regimen (PREMIER), Phase I
Acute Coronary Syndrome
Primary: Change in the Total Atheroma Volume of the Target Coronary Artery From Baseline to 12 Weeks Post-PCI as Assessed Via Intravascular Ultrasound With Virtual Histology…
Phase 3 N=29 Clinical Study to Compare Dental Plaque Control
Dental Plaque
Primary: Dental Plaque Index — 3.12; 2.90; 2.92; 2.94 Units on a scale — p=<0.05
Phase 2 N=27 Is an Antiplaque Chewing Gum (30 mg) Able to Reduce Dental Plaque in a Healthy Population?
Plaque Regrowth
Primary: Safety, Tolerability and Effectiveness in Reducing Dental Plaque of KLS-W Delivered in a Chewing Gum Formulation — 0; 0; 0; 0 participants
N/A N=28 Use of Platelet Rich Fibrin in Addition to CAF and SCTG for Treatment of Gingival Recession
Gingival Recession
Primary: Recession Depth — 2; 2; 0; 0 length in millimeters
N/A N=86 Clinical Evaluation of an Experimental Remineralization Product
White Spot Lesion
Primary: White Spot Measurement — 34; 37; 1; 0 Lesions
N/A N=50 Curved Soft-Picks on Plaque Accumulation on Patients With Gingivitis
Gingivitis
Primary: Change in Interproximal Plaque by Modification of the Quigley-Hein Plaque Index at 14 Days — 0.03; -0.07 score on a scale
N/A N=70 Changes in the Risk Factors of Coronary Heart Disease Observed After Scaling and Root Planing
Coronary Heart Disease · Periodontitis
Primary: Change From Baseline in C-Reactive Protein Level at 6 Months — 6.30; 4.94 mg/L
Phase 4 N=135 Six Month Plaque and Gingivitis Study Using Colgate Total Toothpaste
Dental Plaque · Gingivitis
Primary: Dental Plaque Score — 3.53; 3.55; 3.59 units on a scale — p=0.919
N/A N=50 Nobio Clinical Study - Demineralization Prevention With a New Antibacterial Restorative Composite
Dental Caries · Denture, Partial, Removable
Primary: Mineral Loss ΔZ — 235; 774 vol% * μm]
Phase 2 N=39 Dental Plaque Removal Ability of Prototype Power Toothbrush Versus a Manual Toothbrush in Healthy Participants
Dental Plaque
Primary: Change in Whole Mouth Rustogi Modified Navy Plaque Index (RMNPI) Score From Pre-Brushing to Post-Brushing (When Prototype Power Toothbrush [PTB] Was Used in 'Gumline'…
Phase 4 N=179 Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)
Dental Plaque · Gingivitis
Primary: Dental Plaque Scores — 3.33; 3.22; 3.34 units on a scale — p=0.04
Phase 4 N=69 Cetylpyridium Chloride (CPC) Based Chewing Gum and Gingivitis
Gingivitis · Plaque, Dental · Periodontal Diseases
Primary: Degree of Plaque as Assessed by the Turesky Modification of the Quigley-Hein Plaque Index — 0.41; 0.43 score on a scale
N/A N=45 A Study to Investigate the Antimicrobial Activity of 2 Test Toothpastes
Dental Plaque
Primary: Area Under the Curve for Glycolysis (AUCgly(0-90)) of Test Zinc-IPMP and Non-SLS Negative Control — 42.64; 2.46 plaque incubation pH*min — p=<0.0001
N/A N=200 A Clinical Study to Evaluate Effects of an Oral Rinse on Plaque and Gingivitis
Plaque
Primary: Plaque Index Score Per Participant at 6 Months — 2.12; 2.70; 2.23; 2.84 score on a scale — p=<0.0001
N/A N=45 Efficacy of Three Toothpastes Using an in Situ Caries Model
Dental Caries
Primary: Percentage Surface Microhardness Recovery (SMHR) of Phyte (0% 0.425% and 0.85%) at 2 Weeks — 25.53; 26.81; 7.41; 28.88 % SMHR — p=0.7603