Phase 4 N=160 Management of Postoperative Pain After Total Knee Replacement.
Postoperative Pain · Knee Replacement Arthroplasty
Primary: Post-Operative Pain — 2.9; 3.0 units on a scale — p=0.76
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Phase 3 N=234 OxyNorm Capsules in Post-Operative Pain Study
Postoperative Pain
Primary: Visual Analogue Scale (VAS) in Resting Stage at 6hour (6hour±20 Minutes After Administration of First Dose) — 46.21; 45.48; 20.21; 19.94 units on a scale
Phase 4 N=343 PAIN - Postoperative Analgesia INvestigation
Postoperative Pain
Primary: Postoperative Pain as Assessed by a Numeric Pain Scale (NPS) — 5.05; 5.02 units on a scale — p=0.934
N/A N=110 Postoperative Pain Control for Prostatectomy
Prostate Cancer
Primary: Total Milligrams of Opiates — 5.15; 2.52 mg — p=0.0012
Phase 3 N=204 Study to Evaluate Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy
Hemorrhoids
Primary: Area Under the Curve (AUC) of the Numeric Rating Scale at Rest (NRS-R) Pain Intensity Scores — 359; 396 Units on a scale*hours
N/A N=364 Predictors of Postoperative Pain
Postoperative Pain
Primary: Visual Analog Scale (VAS) Pain Score — 38.16 mm
Phase 4 N=180 IV Acetaminophen for Post-Operative Pain Management in Enhanced Recovery After Surgery (ERAS) Population
Abdominal Wall Hernia · Pancreatic Diseases · Bowel Disease
Primary: Postoperative Pain Intensity — 33; 42 Participants
N/A N=69 High Pain Intervention in Cesarean Sections
Other Chronic Postoperative Pain
Primary: Severity of Acute Pain — 46; 31 mm — p=0.05
Phase 4 N=70 Perioperative Administration of Pregabalin for Pain After Mastectomy
Pain, Postoperative
Primary: Pain Scores (Verbal Numerical Rating Scale;VNRS) During Postoperative Hours. — 7; 5; 6; 5 Units on a scale
N/A N=122 Percutaneous Auricular Neuromodulation for Postoperative Analgesia
Postoperative Pain, Acute
Primary: AVERAGE Pain Measured With the Numeric Rating Scale First 5 Postoperative Days — 1; 3 units on a scale
Phase 2 N=120 Local Anesthetics on Postsurgical Analgesia Following Posterior Colporrhaphy
Postoperative Pain
Primary: Change in Vaginal Pain Scores Using the Defense and Veterans Pain Rating Scale (Visual Analog Scale) Between Bupivacaine Alone Versus Exparel® Following Posterior…
N/A N=73 PuraBond® and Pain Following Resection of Oral or Oropharyngeal Mucosal Lesions
Pain · Hemorrhage · Hemostatics
Primary: Change From Baseline in Cumulative Pain on the Visual Analogue Scale (VAS) at Postoperative Week 1 — 3.27; 4.35 score on a scale
N/A N=278 Post-operative Patient Positioning Device for Improvement of Post-Operative Pain
Pain, Postoperative
Primary: Total Morphine Milliequivalent (MME) Use Postoperatively After Cesarean Delivery — 52; 68 Morphine milligram equivalents
N/A N=100 Perioperative Pain Management In Spine Surgery Patients: Part I
Pain
Primary: Immediate Postoperative Pain Control — 6.6; 6.8 score on a scale
N/A N=122 Protective Analgesia for Postoperative Pain Relief Following Day Case Oral Surgery
Postoperative Pain · Wisdom Tooth
Primary: Number of Patients Needing Rescue Medication — 32; 29 Participants
N/A N=16 Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain
Phantom Limb Pain · Postoperative Pain · Neuroma
Primary: Average Phantom Limb Pain (PLP) Score — 4.1; 3.1; 2.2; 3.0 score on a scale
Phase 3 N=161 Postoperative Thoracic Epidural Analgesia Versus Intravenous Patient-Controlled Analgesia For Liver and/or Pancreas
Liver Cancer · Pancreatic Cancer
Primary: Postoperative Pain Experience — 78.6; 105.2 score on a scale* hour
Phase 4 N=99 Perioperative Administration of Pregabalin for Pain After Robot-assisted Endoscopic Thyroidectomy
Pain, Postoperative
Primary: Pain Scores (VNRS) at 1, 6, 24, 48 Hours Postoperatively. — 6; 6; 3; 2 VNRS
N/A N=120 Postoperatory Analgesia After Total Knee Arthroplasty
PAIN
Primary: Postoperatory Analgesia After Total Knee Arthroplasty Comparing Femoral and Sciatic-femoral Block — 2; 2.8; 1.5 units on a scale
N/A N=7,103 Non-pharmacological Pain Management After Surgery
Surgical Procedure, Unspecified
Primary: PROMIS-CAT Pain — 59.32; 59.96; 56.94; 56.06 score on a scale
Phase 4 N=67 ON-Q Pump Infusion of Ketorolac and Ropivacaine at the Wound Site for Postoperative Pain Management
Postoperative Pain
Primary: Pain Scores at Rest — 6.7; 6.2 units on a scale
N/A N=86 Pregabalin for the Treatment of Pain After Posterior Spinal Fusions
Lumbar Spinal Fusions
Primary: Patient Controlled Analgesia (PCA) Hydromorphone Usage — 44; 39 mL
N/A N=85 Post Operative Pain Control Using Ropivacaine and the ON-Q System in the Adult Pectus Excavatum Patient
Pectus Excavatum
Primary: Hospital Length of Stay — 3.5; 3.3 days — p=0.55
N/A N=150 Postoperative Pain Control Following Hysteroscopy
Postoperative Pain · Postoperative Nausea · Analgesia
Primary: Visual Analog Scale (VAS) — 2.49; 4.44; 1.23; 2.40 score on a scale
Phase 2 N=24 Local Infusion of Ropivacaine for Post-Op Pain Control After Osseocutaneous Free Flaps
Head and Neck Cancer · Free Tissue Transfer
Primary: Post-Operative Pain at Donor-Site — 52.40; 41.14; 41.00; 40.88 score on a scale
N/A N=132 Postoperative Environment on Pain Following Pelvic Reconstructive Surgery
Postoperative Pain
Primary: Visual Analog Scale (VAS) Score for Pain — 28.0; 24.5 millimeter (mm) — p=0.57
N/A N=160 Patient-Driven Analgesic Protocol Selection for Post-Cesarean Pain Management
Postoperative Pain
Primary: Opioid Consumption in the 0-48 Hour Study Periods. — 10; 5; 10; 5 milligram morphine equivalents (MMEQ)
Phase 3 N=105 Pain Outcomes of Non-opioid vs. Opioid Analgesia for Kidney Stone Surgery.
Nephrolithiasis
Primary: Satisfaction With Pain Relief — 8.70; 8.85 score on a scale — p=0.70
N/A N=87 Occurrence of Post-op Pain Following Gentlewave
Root Canal Infection · Endodontic Disease · Endodontic Inflammation
Primary: Level of Post-operative Pain (2018-2019) — 23.2; 11.56 score on VAS scale
Phase 4 N=129 Pre-incision Versus Post-incision Local Anesthetic During Robotic Sacrocolpopexy
Pain, Postoperative
Primary: Likert-pain Scale Score on Postoperative Day One — 2.94; 3.27 units on a scale