Phase 4 N=160 Management of Postoperative Pain After Total Knee Replacement.
Postoperative Pain · Knee Replacement Arthroplasty
Primary: Post-Operative Pain — 2.9; 3.0 units on a scale — p=0.76
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=100 Perioperative Pain Management In Spine Surgery Patients: Part I
Pain
Primary: Immediate Postoperative Pain Control — 6.6; 6.8 score on a scale
N/A N=7,103 Non-pharmacological Pain Management After Surgery
Surgical Procedure, Unspecified
Primary: PROMIS-CAT Pain — 59.32; 59.96; 56.94; 56.06 score on a scale
N/A N=110 Postoperative Pain Control for Prostatectomy
Prostate Cancer
Primary: Total Milligrams of Opiates — 5.15; 2.52 mg — p=0.0012
Phase 4 N=180 IV Acetaminophen for Post-Operative Pain Management in Enhanced Recovery After Surgery (ERAS) Population
Abdominal Wall Hernia · Pancreatic Diseases · Bowel Disease
Primary: Postoperative Pain Intensity — 33; 42 Participants
N/A N=160 Patient-Driven Analgesic Protocol Selection for Post-Cesarean Pain Management
Postoperative Pain
Primary: Opioid Consumption in the 0-48 Hour Study Periods. — 10; 5; 10; 5 milligram morphine equivalents (MMEQ)
N/A N=110 Pain Management for Pectus Excavatum Repair
Postoperative Pain
Primary: Length of Hospitalization — 4.54; 4.25 days
Phase 4 N=22 Opioid Free Management After Ureteroscopy
Kidney Stone
Primary: Amount of Pain Medication Used — 7.3; 6.67 tablets
Phase 3 N=105 Pain Outcomes of Non-opioid vs. Opioid Analgesia for Kidney Stone Surgery.
Nephrolithiasis
Primary: Satisfaction With Pain Relief — 8.70; 8.85 score on a scale — p=0.70
N/A N=86 Pregabalin for the Treatment of Pain After Posterior Spinal Fusions
Lumbar Spinal Fusions
Primary: Patient Controlled Analgesia (PCA) Hydromorphone Usage — 44; 39 mL
Phase 4 N=180 Minimal Opioid Use After Total Hip Replacement (THR)
Osteoarthritis, Hip
Primary: Opioid Use — 30; 22.5; 15 Oral Morphine Equivalent (mg)
N/A N=63 NSS-2 BRIDGE Device in Post-Operative Pain Management
Acute Pain · Surgery · Abdominal Cancer
Primary: Opioid Consumption — 24; 38; 24; 27 oral morphine mg equivalents (OME)
Phase 4 N=67 ON-Q Pump Infusion of Ketorolac and Ropivacaine at the Wound Site for Postoperative Pain Management
Postoperative Pain
Primary: Pain Scores at Rest — 6.7; 6.2 units on a scale
Phase 3 N=234 OxyNorm Capsules in Post-Operative Pain Study
Postoperative Pain
Primary: Visual Analogue Scale (VAS) in Resting Stage at 6hour (6hour±20 Minutes After Administration of First Dose) — 46.21; 45.48; 20.21; 19.94 units on a scale
Phase 4 N=48 Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty
Pain, Postoperative · Urethral Stricture
Primary: Participant Pain Control: Numerical Rating Scale (NRS) — 1.2; .625 score on a scale
Early Phase 1 N=46 Pain Management in Teeth With Reversible Pulpitis
Reversible Pulpitis · Ibuprofen
Primary: Change in Pain Intensity From Baseline (Pre-Operative) to Immediately During the Procedure (Day 0), Measured by the Visual Analogue Scale (VAS) — 5.05; 0.64 score on a…
Phase 3 N=161 Postoperative Thoracic Epidural Analgesia Versus Intravenous Patient-Controlled Analgesia For Liver and/or Pancreas
Liver Cancer · Pancreatic Cancer
Primary: Postoperative Pain Experience — 78.6; 105.2 score on a scale* hour
Phase 3 N=204 Study to Evaluate Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy
Hemorrhoids
Primary: Area Under the Curve (AUC) of the Numeric Rating Scale at Rest (NRS-R) Pain Intensity Scores — 359; 396 Units on a scale*hours
N/A N=150 Postoperative Pain Control Following Hysteroscopy
Postoperative Pain · Postoperative Nausea · Analgesia
Primary: Visual Analog Scale (VAS) — 2.49; 4.44; 1.23; 2.40 score on a scale
Phase 4 N=120 Multimodal Pain Management for Cesarean Delivery
Pain
Primary: Total Opioid Intake in Morphine Milligram Equivalents in the First 48 Hours After Cesarean Delivery (CD) — 42; 49.5 morphine milligram equivalents
Phase 3 N=68 Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy
Pain, Postoperative
Primary: Total Opioid Pain Medications Required 0-3h Post op in Morphine Milligram Equivalents (MME) — 2.00; 5.32 morphine milligram equivalents (MME)
Phase 4 N=343 PAIN - Postoperative Analgesia INvestigation
Postoperative Pain
Primary: Postoperative Pain as Assessed by a Numeric Pain Scale (NPS) — 5.05; 5.02 units on a scale — p=0.934
N/A N=16 Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain
Phantom Limb Pain · Postoperative Pain · Neuroma
Primary: Average Phantom Limb Pain (PLP) Score — 4.1; 3.1; 2.2; 3.0 score on a scale
N/A N=120 Postoperatory Analgesia After Total Knee Arthroplasty
PAIN
Primary: Postoperatory Analgesia After Total Knee Arthroplasty Comparing Femoral and Sciatic-femoral Block — 2; 2.8; 1.5 units on a scale
Phase 4 N=167 Postoperative Pain Management in Patients Undergoing Intramedullary Nail Fixation After Tibia and Femoral Fractures
Femur Fracture · Tibial Fractures
Primary: 12hrs VAS Pain Scores — 7.6; 7.9; 7.3; 7.2 score on a scale — p=0.215
Phase 4 N=100 Multimodal Versus Opioid aNalgesia in carDiAc Surgery
Postoperative Pain · Postoperative Delirium
Primary: Postoperative Pain After Cardiac Surgery — 2.28; 2.17 units on a scale
Phase 4 N=66 IV Acetaminophen for Acute Post Operative Pain in C-Section Patients
Post-operative Pain
Primary: Opioid Requirements in Cesarean Section (C-section) Patient Population — 44; 48; 58; 57 mg
Phase 3 N=58 Perioperative Methadone Use to Decrease Opioid Requirement in Pediatric Spinal Fusion Patients
Scoliosis · Pain
Primary: Post-operative Opioid Consumption (mg/kg) — 0.267; 0.340 mg/kg — p=<0.05
Phase 2 N=141 Postoperative Pain Management in Rhinoplasty
Pain, Postoperative
Primary: Pain Intensity Visual Analog Scale (VAS)- 0-100 (0- no Pain and 100- Most Severe Pain) — 44; 41 score on a scale — p=0.156
N/A N=178 Post-op Acetaminophen vs NSAID Use on Lumbar Spinal Fusion Outcomes
Lumbar Osteoarthritis · Spondylosis · Lumbar Disc Disease
Primary: Perioperative Opioid Use — 86.25; 306.6; 192.4; 88.95 oral morphine equivalents (OME) (mmg) — p=<0.001