N/A N=47 Post-Operative Cognitive Dysfunction in Normal Aging Patients Undergoing Elective Orthopedic Surgery
Post Operative Cognitive Dysfunction
Primary: Presence of Post Operative Cognitive Dysfunction (POCD) — 15 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=203 Postoperative Cognitive Dysfunction as Geriatric Syndrome
Cognitive Dysfunction
Primary: Postoperative Cognitive Dysfunction - Results of MMSE Before Operation — 79; 43; 37; 5 Participants — p=<0.0001
N/A N=45 Prevention of Early Postoperative Decline
Delirium · Postoperative Cognitive Dysfunction
Primary: Feasibility of Providing a Neurocognitive Training Program to Elderly Cardiac Surgical Patients - Enrollment — 45 Participants
Phase 4 N=135 Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy
Delirium · Cognitive Impairment · Post-traumatic Stress Disorder
Primary: Efficacy of Low-dose Haloperidol in Reducing Delirium Incidence — 15; 19 Participants
N/A N=200 Post-Operative Delirium in Elderly Surgical Patients
Hip Fractures · Delirium
Primary: Number of Participants With the Presence of Delirium as Assessed by the Confusion Assessment Method — 39; 34 Participants
N/A N=30 Assessment of Cognitive Function After Surgery in Two Types of Anesthesia in Patients Operated for Breast Cancer
Patients With Breast Cancer and Breast Surgery Requiring
Primary: Presence of Cognitive Impairment — 29.5; 29 score on a scale
N/A N=91 Postoperative Delirium: Brain Vulnerability and Recovery
Delirium · Postoperative Complications
Primary: EEG During Delirium and After Recovery and in Patient Controls.
Phase 3 N=72 Postoperative Consequences of Intraoperative NOL Titration
Anesthesia; Adverse Effect
Primary: Pain Scores at 10-minute Intervals for the Initial Hour of Recovery — 0; 0; 1.0; 5.0 score on a scale — p=0.895
N/A N=250 Assessing the Incidence of Postoperative Delirium Following Aortic Valve Replacement
Postoperative Delirium · Aortic Valve Stenosis
Primary: Number of Participants With Postoperative Delirium — 13; 41; 45 Participants — p=<0.0001
N/A N=229 Preoperative Cognitive Screening in Older Spinal Surgical Patients
Cognitive Impairment · Frail Elderly Syndrome
Primary: Delirium by Age — 75; 77 years — p=0.508
N/A N=135 Effect of CPAP on Postoperative Delirium
Sleep Apnea, Obstructive · Delirium
Primary: Presence of Postoperative Delirium — 4.8; 5.1; 7.8; 8.1 units on a scale
Phase 4 N=120 Effect of Intraoperative Dexmedetomidine on Early Postoperative Cognitive Dysfunction
Cognitive Dysfunction
Primary: Number of Cases Developing POCD — 10; 21 Participants
Phase 4 N=60 Comparison of Postoperative Delirium in Patients Anaesthetised With Isoflurane and Desflurane During Spinal Surgery
Postoperative Delirium
Primary: Comparison of Postoperative Delirium(POD) With Isoflurane and Desflurane on Adults Undergoing Spine Surgery — 3; 4; 27; 26 Participants
Phase 4 N=121 Dexmedetomidine and IV Acetaminophen for the Prevention of Postoperative Delirium Following Cardiac Surgery
Delirium
Primary: Incidence of Delirium — 2; 4; 8; 9 Participants
Phase 4 N=100 The Effect of Dexmedetomidine Infusion on Post-operative Cognitive Function and Oxidative Stress in Cardiac Surgery
Oxidative Stress · Cognition Disorders
Primary: Numbers of Participants With Postoperative Cognitive Dysfunction (POCD) — 12; 8 Participants — p=0.289
N/A N=36 Emergence From Anesthesia in Anterior Temporal Lobectomy and Amygdalohippocampectomy Patients
Emergence From Anesthesia
Primary: Volumes of the Hippocampus, Thalamus and Amygdala — 3578; 3903; 3479; 3525 mm3
Phase 2 N=128 REPOSE Study: Reducing Delirium by Enhancing Postoperative Sleep With Suvorexant
Delirium in Old Age
Primary: Total Sleep Time (TST) on the First Postoperative Night — 3.91; 3.84 hours — p=0.853
Phase 3 N=672 The Prevention of Delirium and Complications Associated With Surgical Treatments Multi Center Clinical Trial
Delirium
Primary: Number of Patients With Incidence of Delirium Across All Patients at Baseline and Over Post-operative Days 1-3 — 85; 43 Participants — p=0.912
Phase 3 N=750 Clinical Trial of Gabapentin to Decrease Postoperative Delirium and Pain
Postoperative Delirium · Postoperative Pain · Opioid Use
Primary: Incidence of Postoperative Delirium by Study Group — 84; 72 Participants
Phase 4 N=28 Rivastigmine in the Treatment of Postoperative Delirium: a Pilot Clinical Trial
Delirium · Postoperative Cognitive Dysfunction
Primary: Incidence of POD — 2; 4 participants
Phase 2 N=154 Post-Operative Constipation Following Total Knee Arthroplasty
Constipation
Primary: Bowel Movement (BM) Within 3 Days of Surgery — 29; 32 Participants — p=0.41
N/A N=200 Preoperative Cognitive Screening of Elderly Surgical Patients
Cognitive Impairment
Primary: Number of Patients With Probable Cognitive Impairment — 23; 22 Participants
Phase 4 N=404 Perioperative Cognitive Function - Dexmedetomidine and Cognitive Reserve
Postoperative Delirium · PD · Postoperative Cognitive Dysfunction
Primary: Delirium Battery — 23; 23; 6; 8 Participants
Phase 4 N=285 Dexmedetomidine and Delirium in Patients After Cardiac Surgery
Delirium · C.Surgical Procedure; Cardiac · Postoperative Complications
Primary: Incidence of Postoperative Delirium — 7; 11 Participants — p=0.341
N/A N=54 Postoperative Virtual Clinical Encounters
Pelvic Organ Prolapse
Primary: Patient Satisfaction Via the Patient Satisfaction Questionnaire -18 — 80.7; 81.2 score on a scale
N/A N=22 Improved Patient Recovery After Anesthesia With Hypercapnia Hyperpnoea
Hypercapnia
Primary: Recovery From Anesthesia — 53.0; 62.9 minutes — p=>0.05
Phase 2 N=86 The Influence of Postoperative Analgesia on Systemic Inflammatory Response and POCD After Femoral Fractures Surgery
Postoperative Cognitive Dysfunction
Primary: Interleukin-6 Concentration in Peripheral Blood. — 27.2; 26.6; 104; 97.7 pg/ml
N/A N=1,560 EEG - Guided Anesthetic Care and Postoperative Delirium
Delirium · Emergence Delirium · Anesthesia, General
Primary: Number of Participants With Postoperative Delirium — 8; 9 Participants
N/A N=38 Examining the Association Between Pre-existing Sleep Disturbance and Postoperative Delirium
Delirium
Primary: Association Between Sleep and POD — 278.5; 313.5 Minutes
Phase 4 N=100 Desflurane or Propofol Anesthesia in Elderly Obese Patients Undergoing Total Knee Replacement
Obesity · Arthritis
Primary: Assessment of Delirium — 0; 0 participants