Phase 4 N=45 Premedication for Non-Emergency Endotracheal Intubation In the NICU
Respiratory Distress Syndrome
Primary: Present the Percentage of Participants With an Excellent Ease of Intubation Rating — 91; 17 % reported as excellent
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=81 Intranasal Dexmedetomidine Premedication
Benign Neoplasm of Vocal Fold - Glottis
Primary: Extubation Time After Intranasal Dexmedetomidine Premedication — 18.58; 17.16; 16.21; 14.74 min
Phase 3 N=75 Intranasal Dexmedetomidine Premedication in Children
Preoperative Sedation
Primary: University of Michigan Sedation Scale — 15; 25; 22; 11 Participants — p=0.025
N/A N=45 Hydroxyzine Dihydrochloride Premedication is a Necessity for Strabismus Surgery
Strabismus · Reflex, Oculocardiac · Hydroxyzine
Primary: Heart Rate-1 — 114.4; 125.8; 122.3 beats per minute
Phase 3 N=86 A Comparison of Midazolam and Zolpidem as Oral Premedication in Children
Parental/Caregiver Anxiety · Child's Anxiety
Primary: Patient Anxiety at the Time of Separation — 26.69; 30.00 units on a scale
Phase 2 N=55 PREMIX vs PREMED Intranasal Lidocaine and Midazolam
Pain
Primary: Procedural Distress, OSBD-R — 6.4; 7 Units on a scale
Phase 3 N=173 Premedication Trial for Tracheal Intubation of the NEOnate
Premedication · Endotracheal Intubation
Primary: Number of Patients With Prolonged Desaturation — 54; 53 Participants — p=0.38
Phase 4 N=80 Premedication With Melatonin and Alprazolam Combination Versus Alprazolam or Melatonin Alone
Anxiety
Primary: Change in VAS Anxiety Score Relative to Baseline After Premedication — 0.35; 0.70; 0.65; 0.25 Centimeter
Phase 4 N=50 Alternative Sedation During Bronchoscopy
Sedation
Primary: Decreased Minute Ventilation — 0.736; 0.764 percentage of baseline — p=<0.0001
Phase 4 N=139 Efficacy of Propofol or Midazolam Compare to Placebo for Preoperative Medication
Elective Orthopedic Surgery
Primary: Scores on the Verbal Rating Scale For Anxiety — 1.8; 2.3; 2.8 Scores on a Scale (0-10)
Phase 4 N=50 Analgetic and Anxiolytic Effect of Preoperative Pregabalin
Intervertebral Disk Displacement · Disk Prolapse
Primary: Mean VAS Pain (Visual Analogue Scale)at Rest (0-100 mm) — 11.7; 22.5 Units on a scale
Phase 4 N=15 Intranasal Midazolam in Children as a Pre-Operative Sedative
Sedation, Conscious
Primary: Sedation Scale Score — 0; 0; 0; 1 participants — p=0.99
Phase 4 N=135 Propofol vs. Midazolam-based Balanced Propofol for Nonanesthesiologist Moderate Sedation in Colonoscopy
Procedural Sedation
Primary: Level of Sedation Throughout the Entire Procedure — 22; 9; 10; 1 participants
Phase 4 N=304 Adjunct Sedatives in Endoscopic Ultrasound (EUS) and Endoscopic Retrograde Cholangiopancreatography (ERCP) Procedures
Endoscopic Ultrasound (EUS) · Endoscopic Retrograde Cholangiopancreatography (ERCP)
Primary: Average Percentage of Sedation Failures — 14; 13; 5 percentage of participants
N/A N=60 Conscious Sedation for Epilepsy Surgery
Epilepsy
Primary: Patients Satisfaction — 6.33; 6.45 score on a scale
Phase 4 N=42 Intranasal Midazolam in Children as a Pre-Operative Sedative - Part 2
Sedation
Primary: Pediatric Pre-Induction Anesthesia Scale at Time of Mask Placement — 11; 3; 6; 1 Participants — p=0.39
N/A N=75 Safety and Efficacy of Oral Midazolam for Perioperative Anxiety Relief of Patients Undergoing Mohs Micrographic Surgery
Basal Cell Carcinoma · Squamous Cell Carcinoma · Skin Cancer
Primary: Patient Anxiety at Baseline — 1.3; 1.4; 3.4 units on a scale
Phase 3 N=98 Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel
Anatomic Stage 0 Breast Cancer AJCC v8 · Anatomic Stage I Breast Cancer AJCC v8 · Anatomic Stage IA Breast Cancer AJCC v8
Primary: Proportion of Patients With Grade 2 or Greater Reactions That Require Parenteral Rescue Medications to Treat an Infusion Hypersensitivity Reaction (HSR) After the First…
Phase 4 N=90 Preemptive Local Anesthesia in Vaginal Surgery
Pain, Postoperative
Primary: Visual Analogue Scale (VAS) Pain Score — 2.5; 4.4 points on a scale — p=.003
N/A N=70 Nasal Versus Oral Midazolam Sedation in Routine Pediatric Dental Care
Conscious Sedation
Primary: Number of Participants Compliant With Oral or Nasal Midazolam Administration — 11; 4; 14; 18 Participants
Phase 4 N=200 Combination of Magnesium and Lidocaine for the Pretreatment of Pain That is Caused by the Injection of Propofol
General Anesthesia · Intravenous Anesthesia
Primary: Percentage of Participants Reporting Pain With Injection of Propofol — 29; 57; 41; 46 percentage of patients reporting pain
Phase 4 N=99 Pre-medication With Alfentanil vs Placebo During ECT
Blood Pressure · Electroconvulsive Therapy
Primary: Systolic Blood Pressure Change — 22.011; 38.908 mmHg
Phase 4 N=109 Dexmedetomidine in Pediatric Tonsillectomy
Pediatric Adenotonsillectomy · Post Operative Analgesia
Primary: Amount of Post-Operative Rescue Morphine Required for Analgesia — 45.2; 37.0; 43.3; 36.5 ug/kg
Phase 4 N=39 The Synergistic Effect of Dexmedetomidine on Propofol for Sedation for Pediatric Endoscopy
Anesthesia
Primary: Propofol Requirements With Pre-treatment of Dexmedetomidine With Children Who do Not Receive Dexmedetomidine. — 0.4; 0.23 mg/kg/min
N/A N=250 Preoperative Survey to Evaluate Patient Allergy
Allergy Drug · Allergic Reaction · Pediatric
Primary: True Allergy (Consistent With an IgE-mediated Reaction) — 135 Allergies
Phase 3 N=50 Sedation Using Intranasal Dexmedetomidine in Upper Gastrointestinal Endoscopy
Gastrointestinal Disease
Primary: Consumption of Rescue Patient Controlled Propofol — 42.4; 28.6 mg
N/A N=48 Should Chronic Stimulant Medications be Continued Preoperatively in Patients With Attention Deficit Hyperactivity Disorder(ADHD)
Attention Deficit Hyperactivity Disorder
Primary: Heart Rate — 96.7; 88 BPM
Phase 3 N=137 Decrease Emergence Agitation and Provide Pain Relief for Children Undergoing Tonsillectomy & Adenoidectomy
Obstructive Sleep Apnea
Primary: Emergence Agitation and Pain — 14; 10; 4; 3 units on a scale — p=.001
Phase 3 N=60 A Comparison of Oral Sedation-related Events of Three Multiagent Oral Sedation Regimens in Pediatric Dental Patients
Anxiety, Dental · Dental Decay
Primary: Incidence of Adverse Sedation-Related Events in Musculoskeletal System During Sedation — 2.8; 3; 2.5500 score on a scale — p=0.016
Early Phase 1 N=300 Sedation Regimens in GI Endoscopy
Anesthesia · Endoscopy · Colonoscopy
Primary: Pain Felt During the Procedure — 0.29; 0.30 score on a scale