N/A N=60 Conscious Sedation for Epilepsy Surgery
Epilepsy
Primary: Patients Satisfaction — 6.33; 6.45 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=139 Efficacy of Propofol or Midazolam Compare to Placebo for Preoperative Medication
Elective Orthopedic Surgery
Primary: Scores on the Verbal Rating Scale For Anxiety — 1.8; 2.3; 2.8 Scores on a Scale (0-10)
Phase 3 N=86 A Comparison of Midazolam and Zolpidem as Oral Premedication in Children
Parental/Caregiver Anxiety · Child's Anxiety
Primary: Patient Anxiety at the Time of Separation — 26.69; 30.00 units on a scale
Phase 4 N=105 Sedation Methods During Cataract Surgery
Phacoemulsification · Cataract
Primary: Eye Mobility During Surgery (See Link to Study Protocol for Scale) — 1.39; 1.41; 1.31 units on a scale
Early Phase 1 N=300 Sedation Regimens in GI Endoscopy
Anesthesia · Endoscopy · Colonoscopy
Primary: Pain Felt During the Procedure — 0.29; 0.30 score on a scale
Phase 4 N=50 Dexmedetomidine vs Propofol TIVA (Total Intravenous Anesthesia) and Interscalene Block
Shoulder Pain
Primary: Number of Participants That Need an Airway Intervention. — 0; 5 participants
N/A N=81 Intranasal Dexmedetomidine Premedication
Benign Neoplasm of Vocal Fold - Glottis
Primary: Extubation Time After Intranasal Dexmedetomidine Premedication — 18.58; 17.16; 16.21; 14.74 min
Phase 4 N=135 Propofol vs. Midazolam-based Balanced Propofol for Nonanesthesiologist Moderate Sedation in Colonoscopy
Procedural Sedation
Primary: Level of Sedation Throughout the Entire Procedure — 22; 9; 10; 1 participants
Phase 4 N=327 Oral Versus Intravenous Sedation for Ocular Procedures
Surgery · Sedation
Primary: Patient Satisfaction — 5.37; 5.23; 5.37; 5.05 score on a scale — p=<0.05
Phase 4 N=114 Propofol and Dexmedetomidine Versus a Propofol Only Regimen for Sedation During Colonoscopy
Colonoscopy
Primary: Percentage of Subjects Ready for Discharge in Each Group at 30 Minutes Post Procedure — 26; 44 Participants
N/A N=75 Safety and Efficacy of Oral Midazolam for Perioperative Anxiety Relief of Patients Undergoing Mohs Micrographic Surgery
Basal Cell Carcinoma · Squamous Cell Carcinoma · Skin Cancer
Primary: Patient Anxiety at Baseline — 1.3; 1.4; 3.4 units on a scale
Phase 4 N=50 Alternative Sedation During Bronchoscopy
Sedation
Primary: Decreased Minute Ventilation — 0.736; 0.764 percentage of baseline — p=<0.0001
N/A N=93 Educational Video and Peri-operative Anxiety
Ambulatory Surgical Procedures · Anxiety Disorders
Primary: VAS-A Score Anxiety Level (Adapted Visual-Analogue Scale) — 1.22; 1.02 score on a scale
N/A N=1,057 Preoperative Education
Postoperative Pain
Primary: Opioid Consumption — 23; 26 Morphine milligrams equivalent — p=0.890
Phase 4 N=144 A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation
Anesthesia
Primary: Respiratory Events Requiring Intervention — 17; 2 Participants
Phase 4 N=60 Does Preop Midazolam Maintain Blood Glucose Norms in the Non Diabetic Perioperative Period
Hernia
Primary: Maximum Perioperative Blood Glucose Level of 30 Minute Interval Measurements — 114.0; 108.0 mg/dL — p=0.87
N/A N=30 Guided Meditation to Decrease Perioperative Anxiety and Increase Patient Intraoperative Compliance in Vascular Surgery
Peripheral Vascular Disease
Primary: Feasibility of Implementing Preoperative Guided Meditation — 15; 14 Participants
Phase 4 N=80 Premedication With Melatonin and Alprazolam Combination Versus Alprazolam or Melatonin Alone
Anxiety
Primary: Change in VAS Anxiety Score Relative to Baseline After Premedication — 0.35; 0.70; 0.65; 0.25 Centimeter
Phase 4 N=15 Intranasal Midazolam in Children as a Pre-Operative Sedative
Sedation, Conscious
Primary: Sedation Scale Score — 0; 0; 0; 1 participants — p=0.99
N/A N=11 Sedation in Patients at Risk for Upper Airway Collapse
Obstructive Sleep Apnea
Primary: Respiratory Disturbance Index — 57.52; 21.32 events per hour
Phase 3 N=50 Sedation Using Intranasal Dexmedetomidine in Upper Gastrointestinal Endoscopy
Gastrointestinal Disease
Primary: Consumption of Rescue Patient Controlled Propofol — 42.4; 28.6 mg
Phase 3 N=60 A Comparison of Oral Sedation-related Events of Three Multiagent Oral Sedation Regimens in Pediatric Dental Patients
Anxiety, Dental · Dental Decay
Primary: Incidence of Adverse Sedation-Related Events in Musculoskeletal System During Sedation — 2.8; 3; 2.5500 score on a scale — p=0.016
Phase 3 N=160 Music vs Midazolam During Preop Nerve Block Placement
Anxiety · Peripheral Nerve Block
Primary: Anxiety Levels — 33.3; 30; 30; 23.3 score on a scale
N/A N=30 Assessment of Cognitive Function After Surgery in Two Types of Anesthesia in Patients Operated for Breast Cancer
Patients With Breast Cancer and Breast Surgery Requiring
Primary: Presence of Cognitive Impairment — 29.5; 29 score on a scale
Phase 4 N=42 Intranasal Midazolam in Children as a Pre-Operative Sedative - Part 2
Sedation
Primary: Pediatric Pre-Induction Anesthesia Scale at Time of Mask Placement — 11; 3; 6; 1 Participants — p=0.39
Phase 4 N=40 Sedation Effect of Dexmedetomidine Versus Remifentanil to Fibreoptic Intubation
Intubation; Difficult
Primary: Endoscopy Scores — 3; 2 units on a scale
N/A N=180 Improving Sedation of Children Undergoing Procedures in the Emergency Department
Anxiety
Primary: Change in CHEOPS Score Measured Level of Sedation From Baseline (Presentation in ED, Before Sedation) to Start of Procedure (Laceration Repair). — 2; 2; 1 Scores on a…
N/A N=73 Effect of Sedation on Diagnostic Injections
Sacroiliac Joint Pain · Sympathetically Maintained Pain
Primary: Pain Score — 2.2; 3.4 units on a scale
N/A N=150 Patient-controlled Sedation With Propofol Versus Combined Sedation During Bronchoscopy
Sedation, Bronchoscopy
Primary: Discharge Assessment Using PADSS After 2 Hours Number of Patients Reaching PADSS Score 10 After 2 Hours — 19; 30; 45 Participants
Phase 3 N=75 Intranasal Dexmedetomidine Premedication in Children
Preoperative Sedation
Primary: University of Michigan Sedation Scale — 15; 25; 22; 11 Participants — p=0.025