N/A N=80 Knee Bracing for People With Patellofemoral Osteoarthritis
Knee Osteoarthritis
Primary: Change in Pain on the VIsual Analog Scale (VAS) — -.068 change in units on a scale from baseline
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=260 Exploratory Study of PENNSAID Gel to Treat Symptoms of Knee Osteoarthritis
Osteoarthritis of the Knee
Primary: Pain When Walking On A Flat Surface — 0; 1; 8; 4 Participants
N/A N=3,000 Development of an Osteoarthritis (OA) Care Plan to Improve Process and Quality of OA Treatment Decisions
Osteo Arthritis Knee · Osteoarthritis, Hip
Primary: Differences in Decision Conflict Scale With ASK vs Usual Care — 25.1; 26.0 Score on a scale
N/A N=50 Osteoarthritis Structural Changes Assessed by Magnetic Resonance Imaging and Neuropathic Pain in Knee Osteoarthritis
Neuropathic Pain · Knee Osteoarthritis
Primary: Osteoarthritis Structural Changes Assessed by Quantitative Magnetic Resonance Imaging With and Without Neuropathic Pain — 14; 7; 5; 1 participants
N/A N=62 Factors Associated With Radiographic Pathophysiology for Trapeziometacarpal Arthrosis in Patients Not Seeking Care for This Condition
Trapeziometacarpal Arthrosis
Primary: Factors Associated With Eaton Classification of Trapeziometacarpal Arthrosis: Age — 61; 66; 75 Years
N/A N=300 Patient and Provider Interventions for Managing Osteoarthritis in Primary Care
Osteoarthritis
Primary: Western Ontario and McMasters Universities Osteoarthritis Index (WOMAC) — 48.4; 48.4; 43.5; 41.2 units on a scale — p=0.158
N/A N=41 Hip Osteoarthritis: Effects of Exercise Programs on Pain and Disability
Hip Osteoarthritis
Primary: Change in 6-minute Walk Test — 22; 49 meters
Phase 2 N=41 A Pilot Study Assessing the Treatment Responsiveness of a Novel Osteoarthritis Stiffness Scale
Osteoarthritis, Knee
Primary: Sum of Change in Brief Arthritis Stiffness Scale (BASS) Scores Over the 4-day Treatment Period — -12.6; -13.6; -11.7; -2.3 Scores on a scale
Phase 2 N=44 A Study to Investigate the Efficacy and Safety of GSK3196165 in Inflammatory Hand Osteoarthritis
Osteoarthritis
Primary: Change From Baseline in 24-hour Average Hand Pain Intensity, Averaged Over the 7 Days Prior to Week 6 — -1.34; -1.70 Scores on scale — p=0.442
Phase 2 N=100 RANKL-blockade for the Treatment of Erosive Osteoarthritis (OA) of Interphalangeal Finger Joints
Hand Osteoarthritis
Primary: Total Ghent University Scoring System (GUSS) of Target Joints at Week 24 — 162.2; 153.3 units on a scale — p=0.024
Phase 2 N=395 Efficacy and Safety of PG-530742 in the Treatment of Mild to Moderate Knee Osteoarthritis
Osteoarthritis, Knee
Primary: Change in Minimum Joint Space Width in the Medial Compartment of the Tibiofemoral Joint of the Signal Knee After 1 Year of Treatment — -0.1361; -0.0442; -0.2261; -0.2000…
N/A N=60 Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP)
Osteoarthritis
Primary: Change From Baseline to Month 4 for Minutes of Moderate to Vigorous Intensity PA Per Week — 0.78 minutes — p=0.5145
N/A N=38 Geniculate Artery Embolization for Treatment of Osteoarthritis
Osteoarthritis
Primary: Percentage Change in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) - Pain Score — -50.1 Percentage change
N/A N=1,261 Survey of Osteoarthritis Real World Therapies (MK-0663-140)
Osteoarthritis
Primary: Percentage of Participants Who Reported Adequate vs. Inadequate Pain Relief at Baseline — 46.2; 53.8 Percentage of Participants
N/A N=240 Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP) (R33)
Osteoarthritis
Primary: Change From Baseline to Month 6 in Objectively Assessed Physical Activity (Accelerometer) — -2.40; -10.8 Minutes per week — p=0.3086
Phase 2 N=157 Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee
Osteoarthritis, Knee
Primary: Change From Baseline in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Domain Score at Week 2 — -3.64; -3.15 Units on a scale — p=0.39
N/A N=33 A Pilot Randomized Controlled Trial for Hand Osteoarthritis
Hand Osteoarthritis
Primary: Visual Analog Scale (VAS) for Pain in the More Symptomatic Hand That Includes the Most Symptomatic DIP Joint by 24 Weeks of Use of Traction Therapy With Standard of Care…
Phase 3 N=164 A Study on Visco-antalgic Intra-articular Administration in Symptomatic Knee Osteoarthritis
Knee Osteoarthritis
Primary: Change From Baseline in WOMAC VA3.1 Pain Subscale Score at Month 6 — -23.6; -14.1 mm — p=0.141
Phase 3 N=163 Efficacy Study of Condrosulf in the Treatment of Symptomatic OA of the Hand
Osteoarthrosis
Primary: Change in Global Spontaneous Pain Intensity of Target Hand — -20; -11.3 mm — p=0.016
Phase 3 N=380 Effect of Diacerein vs Celecoxib on Symptoms and Structural Changes in Symptomatic Knee Osteoarthritis
Osteoarthritis · Osteoarthritis, Knee
Primary: Change Form Baseline in WOMAC A Pain Subscale — -11.14; -11.82 cm — p=<0.025
Phase 2 N=210 Efficacy and Safety of G001 in Patients With Osteoarthritis (OA) of the Knee
Osteoarthritis, Knee
Primary: Change From Baseline in WOMAC Pain Subscale Score at Week 4/EOT — -5.4; -5.2 score on a scale — p=0.6742
N/A N=7 Preventing Posttraumatic Osteoarthritis With Physical Activity Promotion
Anterior Cruciate Ligament Injuries · Exercise · Cartilage, Articular
Primary: T1rho Relaxation Times in the Medial Femoral Condyle at Baseline — 53.48 ms
Phase 2 N=389 A Study to Evaluate the Safety and Efficacy of Topically Applied TV-45070 (Ointment) in Participants With Primary Osteoarthritis (OA) Affecting a Single Knee
Osteoarthritis of the Knee
Primary: Change From Baseline to Last 5 Days of Treatment in the Average Evening Pain Intensity In the Target Knee When Walking on a Flat Surface Using a Mixed Model for Repeated…
N/A N=24 Group Physical Therapy for Knee Osteoarthritis
Osteoarthritis
Primary: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) — 43.3; 34.1 units on a scale
N/A N=51 Development of a Mind Body Program for Obese Knee Osteoarthritis Patients With Comorbid Depression
Knee Osteoarthritis · Obesity · Depression
Primary: Treatment Adherence — 24; 18 Participants
N/A N=179 Persistent Postoperative Pain and Joint Stiffness After Total Knee Arthroplasty Performed for Osteoarthritis
Pain · Joint Stiffness
Primary: Presence of Persistent Postoperative Pain Using the Numeric Rating Scale (NRS) — 10 Participants
N/A N=40 Muscle Property, Alignment and Joint Loading in People With Knee Osteoarthritis
Osteoarthritis, Knee
Primary: Change of External Knee Adduction Moment as Assessed by Visual Motion Analysis System — 0.50 Nm/kg
N/A N=21 Geniculate Artery Embolization for Knee Pain Secondary to Osteoarthritis (OA)
Osteo Arthritis Knee
Primary: Mean WOMAC Scores at Month 6 — 29; 26 units on a scale
Phase 4 N=500 Patient-Reported Effectiveness and Safety of Etoricoxib in Osteoarthritis (OA)(0663-113)
Pain
Primary: The Percentage of Participants Achieving ≥30% Decrease From Baseline in Pain Intensity as Measured by WOMAC (Western Ontario and McMaster Universities Osteoarthritis…
Phase 4 N=219 Buprenorphine in the Treatment of Osteoarthritis (OA) in the Elderly
Osteoarthritis
Primary: Average Daily Pain Scores - BS11 Pain Scores. — 3; 3 Box Scale 11 boxes