N/A N=155 Treatment of Prolonged Grief Disorder in Combat Veterans
Prolonged Grief Disorder
Primary: Inventory of Complicated Grief - Revised (ICG-R) — 93.15; 93.10 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=39 Ericksonian Hypnosis Versus CBT for Prolonged Grief
Prolonged Grief Symptoms
Primary: Prolonged Grief Scale — 34; 21; 24; 26 points
Phase 2 N=395 A Study of Medication With or Without Psychotherapy for Complicated Grief
Complicated Grief · Bereavement
Primary: Responder Status Based on Complicated Grief Clinical Global Impression-Improvement (CGI-I) Scale — 46; 38; 84; 83 percentage of responders — p=<0.05
N/A N=99 Dementia Caregiver Chronic Grief Management: A Live Online Video Intervention
Chronic Grief · Dementia Family Caregivers
Primary: Marwit-Meuser Caregiver Grief Inventory (MM-CGI) — 12.75; 11.04 units on a scale — p=0.001
N/A N=121 Supporting Family Members With Severe Grief Reaction During the COVID-19 Pandemic
Bereavement · Severe Grief Reaction
Primary: The Inventory for Complicated Grief-revised (ICG-r) Score at 6 Months Post-death — 35; 86 Participants
N/A N=44 Oxytocin and Approach-avoid in Grief
Prolonged Grief Disorder · Bereavement
Primary: Reaction Time (ms) of a Push or Pull of a Joystick in a Standard Interactive Approach/Avoid Task. — 29; 18; 7.5; 13.0 Milliseconds (contrast score)
Phase 4 N=207 PROlonGed ExpoSure Sertraline
Posttraumatic Stress Disorder
Primary: Posttraumatic Stress Disorder (PTSD) Symptoms as Measured by the Clinician Administered Posttraumatic Stress Disorder Scale (CAPS) — 41.7; 43.3; 51.5 Scores on a scale
Phase 2 N=17 Prolonged Exposure and Oxytocin
PTSD
Primary: PTSD Symptom Severity — 13.00; 17.71 scores on a scale
N/A N=174 Psychosocial Rehabilitation After Moral Injury and Loss With Adaptive Disclosure
Post-traumatic Stress Disorder · Moral Injury · Traumatic Loss
Primary: Change in Functional Impairment Assessed Through the Sheehan Disability Scale (SDS) — 20.52; 20.43; 17.39; 18.04 Score on a scale — p=0.03
N/A N=52 Walk With Me for Perinatal Grief
Grief · Traumatic Stress · Usability
Primary: Traumatic Stress - Intrusion Subscale — 2.17; 1.93; 1.32 units on a scale — p=.083
N/A N=88 Post-traumatic Stress Disorder (PTSD) Symptoms in Later Life
Post Traumatic Stress Disorder
Primary: The Trauma History Questionnaire (THQ; Green, 1996) — 5.93; 0.76; 3.81; 0.97 score on a scale
N/A N=52 Prolonged Exposure Therapy for PTSD and Opioid Use Disorder
Post Traumatic Stress Disorder · Opioid-use Disorder
Primary: Change in Posttraumatic Stress Disorder (PTSD) Symptom Severity — -11.4; -12.8; -18.3 Score on a scale
N/A N=261 Improving Psychological Distress Among Critical Illness Survivors and Their Caregivers
Intensive Care Unit Survivors · Informal Caregivers (Family and Friends)
Primary: Hospital Anxiety and Depression Scale Score — 16.6; 15.3; 15.6; 15.9 units on a scale (HADS summary score)
Phase 4 N=37 Combination Treatment for Posttraumatic Stress Disorder (PTSD) After the World Trade Center (WTC) Attack
Posttraumatic Stress Disorder
Primary: Clinician Administered PTSD Scale (CAPS) — 72.6; 65.4; 40.7; 49.0 units on a scale — p=.01
N/A N=151 Depression Prevention in Older Spousally-bereaved Adults
Depression
Primary: Change From Baseline in Depression Symptom Burden at 3 Months — 5.6; 7.4 score on a scale — p=<.05
N/A N=75 Neural Mechanisms of Enhancing Emotion Regulation in Bereaved Spouses
Affect · Bereavement · Emotions
Primary: Self-reported Negative Affect — 1.88; 1.91; 1.70; 1.89 score on a scale — p=0.053
N/A N=150 Experiencing Loss and Planning Ahead Study
Grief
Primary: Pre-death Grief in Dementia Caregiving — 57.6 score on a scale — p=<0.05
N/A N=145 Trauma Informed Guilt Reduction Therapy
Guilt · Shame · Post-traumatic Stress Disorders
Primary: Trauma Related Guilt Inventory - Guilt Severity — 2.5; 2.5; 1.6; 2.2 score on a scale
Phase 3 N=100 Topiramate and Prolonged Exposure
PTSD and Alcohol Use Disorder
Primary: CAPS-5 Change — 36.720; 38.600; 21.006; 29.872 score on a scale
N/A N=8 Peer Enhanced Prolonged Exposure
PTSD
Primary: PE Sessions Attended — 8.63 number of PE sessions attended
N/A N=39 Optimizing Treatment Response in VA Specialized Intensive/Inpatient PTSD Programs
PTSD
Primary: Change in PTSD Symptoms — -23.86; -19.51 score on a scale
Phase 2 N=42 Enhancing Extinction Learning in Post Traumatic Stress Disorder (PTSD)
Chronic Posttraumatic Stress Disorder
Primary: PTSD Symptom Severity-Interview (PSS-I) — 32.07; 31.38; 32.73; 17.10 units on a scale
N/A N=122 Adaptive Disclosure: A Combat-Specific PTSD Treatment
Posttraumatic Stress Disorder
Primary: Clinical Status of Participants as Measured by the Clinician-Administered PTSD Scale for DSM-IV (CAPS-IV) — 8; 11; 7; 4 Participants — p=.05
Phase 2 N=21 Enhancing Prolonged Exposure With Cannabidiol to Treat Posttraumatic Stress Disorder
Posttraumatic Stress Disorder · Stress Disorders, Post-Traumatic
Primary: Clinician Administered PTSD Scale (CAPS-5) — 42.8; 42.9; 15.2; 10.1 score on a scale
N/A N=270 The Impact of the COVID-19 (SARS-CoV-2 Disease) on Psychopathology
Psychosis;Schizophrenic · Personality Disorders · Mood Disorders
Primary: Brief Psychiatric Rating Scale (BPRS) — 29.30; 32.80; 30.25 score on a scale
N/A N=80 Mobile Mindfulness to Improve Psychological Distress After Critical Illness
Psychological Distress · Depression · Anxiety
Primary: Percent of Eligible Participants Who Provided Consent — 90 Participants
N/A N=139 Prevention of Post-traumatic Stress Disorder by Telephone Based Cognitive Behavioral Therapy
Stress Disorder - Post-traumatic (Acute)
Primary: Severity of PTSD Symptoms — 43.4; 43.9 CAPS total Score at treatment end — p=0.927
N/A N=87 Treatment of Older Veterans With Chronic Posttraumatic Stress Disorder
Combat Disorders · Post-traumatic Stress Disorder
Primary: PTSD Checklist (PCL) — 57.46; 59.98; 47.00; 58.06 units on a scale
N/A N=132 Prolonged Exposure (PE) for Post Traumatic Stress Disorder (PTSD): Telemedicine Versus In Person
PTSD
Primary: Treatment Completion — 7.6; 8.6; 3.1; 2.9 sessions
N/A N=13 Perceptual Retraining to Reduce Suicide Risk
Perceptual Olfactory Bias
Primary: Percent Change in Olfactory Perceptual Bias — 21.33; -5 Percent of correctly identified odors — p=.08