N/A N=287 Dual Diagnosis Self-Help Referral
Dual Diagnosis
Primary: Psychiatric Functioning at 6 Months — .333; .387 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=29 Goal Elicitation, Treatment Prioritization, & Electronically-Practiced Discussion for Psychiatry
Mental Illness · Shared Decision Making
Primary: Patient Activation Measure for Mental Health (PAM-MH) — 59.8; 61.6 units on a scale
Phase 4 N=40 Prediction of Clinical Response to SSRI Treatment in Bipolar Disorder Using Serotonin 1A Receptor PET Imaging
Bipolar Disorder
Primary: Montgomery-Asberg Depression Rating Scale — -39.24 Percent change in MADRS from baseline
Phase 2 N=406 Dual Diagnosis Inpatients: Telephone Monitoring RCT to Improve Outcomes
Diagnosis, Dual (Psychiatry)
Primary: Readiness to Attend Substance Use Disorder Continuing Care — 1.8; 2.2 units on a scale — p=<.05
Phase 4 N=183 A Collaborative Care Program to Improve Treatment of Depression and Anxiety Disorders in Cardiac Patients
Depression · Generalized Anxiety Disorder · Panic Disorder
Primary: Change in Mental Health-related Quality of Life From Baseline to 24 Weeks — 8.87; 8.39 units on a scale — p=0.002
N/A N=28 Event Marker Ingested To Trigger Event Recorder 3.0 Psychiatry Study
Bipolar Disorder · Schizophrenia
Primary: Positive Detection Accuracy — 94 percentage of observed ingestions
N/A N=68 Augmenting Hospitalization for Serious Mental Illness: Cognitive Bias Modification
Depression · Bipolar Disorder · Anxiety Disorders
Primary: Clinical Global Improvement Scale (CGIS) — 14; 20 Participants
N/A N=13 Perceptual Retraining to Reduce Suicide Risk
Perceptual Olfactory Bias
Primary: Percent Change in Olfactory Perceptual Bias — 21.33; -5 Percent of correctly identified odors — p=.08
N/A N=115 Digital Data in Mental Health Therapy
Depressive Symptoms · Anxiety Generalized
Primary: Health-related Quality of Life (HRQoL), RAND 36-Item Health Survey Changed Value (Baseline to 2 Months) — -0.89; -1.85 score on a scale
N/A N=9 Investigating the Effectiveness of Telepsychiatry for Treating Major Depression in a Chinese American Nursing Home
Major Depressive Disorder
Primary: Change in Mean Scores on Clinical Global Impressions — -2.1 units on a scale
N/A N=185 Bridge: Proactive Psychiatry Consultation and Case Management for Patients With Cancer
Cancer · Severe Major Depression · Schizophrenia
Primary: Disruptions in Cancer Care — 37; 48; 20; 10 Participants
N/A N=84 Using Computers to Assist in the Diagnosis and Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)
Attention Deficit Hyperactivity Disorder
Primary: Number of Children Diagnosed With ADHD With Structured Diagnostic Assessment — 34; 16 number of kids
N/A N=100 Psychosis: Early Detection, Intervention and Prevention
Prodromal Schizophrenia · Psychotic Disorders · Severe Bipolar Disorder With Psychotic Features
Primary: Onset of Psychosis — 10; 14 percentage of sample converting
Phase 4 N=21 Brexpiprazole for Bipolar Depression
Bipolar Depression
Primary: The Montgomery-Asberg Depression Rating Scale (MADRS) — 31.95; 9.95; 10.95 score on a scale — p=<.001
Phase 4 N=8,144 Study Evaluating The Safety And Efficacy Of Varenicline and Bupropion For Smoking Cessation In Subjects With And Without A History Of Psychiatric Disorders
Smoking Cessation
Primary: Occurrence of Neuropsychiatric (NPS) Adverse Events (AE) - the Primary Study Endpoint — 1.3; 2.2; 2.5; 2.4 percentage of participants — p=0.0652
Phase 2 N=34 Characterization and Sequential Pharmacotherapy of Severe Mood Dysregulation
Severe Mood Dysregulation
Primary: Clinical Global Impression-Severity-Severe Mood Dysregulation — 4.91; 3.62; 4.30; 4.42 units on a scale — p=.58
N/A N=92 Past Pain Experience and Perception of Experimental Pain
Schizophrenia · Major Depression
Primary: Visual Analog Scale Evaluation for the Pre-fixed Pressure Test — 2.8; 2.1; 1.2 units on a scale — p=0.121
N/A N=19 PET Imaging and Olanzapine Treatment in Borderline Personality Disorder
Borderline Personality Disorder
Primary: Change in Brain Metabolism From Baseline to Eight Weeks as Seen in PET Scan — 11.5 Standard uptake value — p=<0.05
Phase 4 N=53 Effects of Treatment on Decision-making in Major Depression
Major Depressive Disorder · Healthy Controls
Primary: Money Earned — 23.2; 25.0; 20.5; 21.9 US Dollars
N/A N=5,325 Digital Detection of Dementia (D Cubed) Studies: D2
Alzheimer Disease and Related Dementias (ADRD)
Primary: 12-Month Cumulative Incidence of ADRD Diagnoses — 213; 134; 355 Number of new ADRD cases — p=0.006
Phase 2 N=97 Assessing Symptomatic Clinical Episodes in Depression
Major Depressive Disorder
Primary: MADRS Score - Overall Change From Baseline — 13.7; 8.8 score on a scale — p=<.001
N/A N=270 The Impact of the COVID-19 (SARS-CoV-2 Disease) on Psychopathology
Psychosis;Schizophrenic · Personality Disorders · Mood Disorders
Primary: Brief Psychiatric Rating Scale (BPRS) — 29.30; 32.80; 30.25 score on a scale
N/A N=87 Mobile Self-Tracking of Mental Health
Schizophrenia · Bipolar Disorder · Schizoaffective Disorder
Primary: Feasibility of Passive Self-tracking of Mental Health — 58 Participants
N/A N=60 Acute Alcohol Response In Bipolar Disorder: a fMRI Study
Bipolar Disorder · Alcohol Drinking · Alcohol Use Disorder
Primary: Level of Intoxication (Subjective Response) on Each Condition Day After Drinking Relative to How They Felt When Arriving to the Lab on That Respective Day )Prior to…
Phase 2 N=41 PH94B in the Treatment of Adjustment Disorder With Anxiety
Adjustment Disorder With Anxious Mood
Primary: Hamilton Anxiety Scale (HAM-A) Score — -12.5; -12.6 score on a scale — p=0.9338
N/A N=14 Interactions of Fronto-Parietal High Frequency rTMS on Anterior Cingulate Cortex Activation in Schizophrenia
Schizophrenia
Primary: Change in BOLD Signal in Anterior Cingulate Cortex — -0.0188; 0.0124 BOLD signal change (Mismatch vs. Match)
N/A N=26 Decision-Making in Bipolar Disorder
Bipolar Disorder
Primary: Change in Vigilance Assessed by the Melbourne Decision Making Questionnaire (MDMQ) — .176 units on a scale
N/A N=32 Improving Identification of Mental Health/Substance Use Disorders in HIV Primary Care: Pilot Clinical Response
HIV Infections
Primary: Mental Health or Substance Use Issue Raised in Visit — 32 Participants
Phase 3 N=75 Aripiprazole for Bipolar Disorder and Alcohol Use Disorder
Bipolar Disorder · Alcoholism · Alcohol Abuse
Primary: Timeline Follow Back (TLFB) — -0.82; -0.71 drinks per drinking day
N/A N=76 PET and MRI Brain Imaging of Bipolar Disorder
Bipolar Disorder · Bipolar Depression · Unipolar Depression
Primary: Post-Lithium Treatment Hamilton Depression Rating Scale (HDRS) — -44.49 Percent Change in HDRS-24 Score