Clinical Trial Search

Primary: Number of Responders at Week 3 — 4; 9; 0; 3 responders

Primary: Hamilton Rating Scale for Depression (24 Item) — 10.94 Units on a Scale

Primary: Change From Baseline in Annual Growth Rate Standard Deviation Score (SDS) for Chronological Age (CA) at Month 36 in Intent-to-Treat (ITT) Population — -1.29; 2.36 SDS

Primary: The Primary Outcome Measure Was Change in a Gait Stride Length Between Groups at 12 and 27 Weeks. — 107.66; 112.29; 103.35 centimeters

Primary: Apathy Evaluation Scale Score at 12 Weeks — 38.2; 43.6 units on a scale — p=<0.05

Primary: Tapping Speed Task - Experiment 1 — 110.52; 128.89; 138.43; 145.86 taps/min

Primary: Neuropsychiatric Inventory (NPI) — -4.5; -3.1 score on a scale

Primary: Change From Baseline in Unified Parkinson's Disease Rating Scale (UPDRS) Part I (Mentation, Behaviour and Mood) — 2; 2 Points on a scale

Primary: Number of Participants Who Achieved Criteria of Obstructive Sleep Apnea in the PVT Assessment — 5; 2 Participants

Primary: Change in Mullen; Visual Reception Sub-scale Scores, Pre- and Post-Intervention — 5.45; 6.61; 6.64; 6.57 score on a scale — p=.211

Primary: Days to Remission of Depression — 10.3; 8.1 Days

Primary: GMDS (Griffiths Mental Development Scale) — 51.96; 51.27; 51.66; 51.67 developpement quotient

Primary: % Change of Hippocampus Volume — -7.63; -7.28 percentage of change

Primary: Correlation Coefficient Between UPDRS III Score and Independent Components Analysis Network Strength in Left Parietal Cortex. — 0.5869 unitless

Primary: Apathy Evaluation Scale (AES) — -1.9; 0.6 units on a scale

Primary: Reaction Time and Variability for Movement Task — 1013.858333; 994.94875; 979.2450877; 910.9120833 milliseconds

Primary: Change in Free-water Accumulation in the Substantia Nigra — 0.0009; 0.0041 arbitrary units (A.U.s)

Primary: Gait Velocity as Measured by GAITRite System — 62.7; 84.3 cm/sec — p=0.03

Primary: Average Gait Speed — 0.973 meters/second — p=0.015