N/A N=809 Randomized Controlled Trial of Game Changers
HIV Prevention
Primary: HIV Testing — 71.60; 71.61 percentage of alters — p=0.95
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=2,700 Randomized Controlled Trial of Routine Screening for IPV
Quality of Life · Disability · Utilization of Health Care Services
Primary: Quality of Life, Physical Health Composite — 46.8; 46.4; 47.2 units on a scale
N/A N=304 Testing a Community-Friendly Risk Reduction Intervention for Injection Drug Users
HIV · Opioid Dependence
Primary: Demonstrated Drug Risk Reduction Skills (0-100%) — 40.60; 42.75 Percentage of correct steps
Phase 4 N=163 A Randomized Clinical Trial of Alcohol Care Management
Alcohol Dependence
Primary: Treatment Engagement — 36; 9 percentage of participants engaged
N/A N=162 Randomized Controlled Trial (RCT) of a Motivational Decision Support System
Schizophrenia
Primary: Number of Subjects That Initiated Cessation Treatment — 27; 36 participants
N/A N=140 Immersive Virtual Reality Intervention for Non-Opioid Pain Management: A Randomized Controlled Trial
Pain · Pain Management
Primary: Pain Intensity Ratings (NRS) — 4.66; 4.94 score on a scale
N/A N=60 Randomized Controlled Trial to Test an Alzheimer's Family Caregiver Intervention in Vietnam
Family Caregivers
Primary: Zarit Burden Inventory-4 — 2.9; 5.5 score on a scale
N/A N=245 A Randomized Controlled Trial of an Antiretroviral Treatment Adherence Intervention for HIV+ African Americans
HIV/AIDS
Primary: Continuous Adherence — 68.80; 70.95; 72.76; 70.02 percentage of doses taken — p=.08
N/A N=319 A Randomized Trial Evaluating Control-IQ+ Technology in Adults With Type 2 Diabetes
Type 2 Diabetes Treated With Insulin
Primary: HbA1c — 8.2; 8.1; 7.3; 7.7 percentage of glycated hemoglobin — p=<0.001
N/A N=60 EHR Embedded Comparative Effectiveness Studies--WWC
Obesity
Primary: Compliance Rate — 87; 76 percentage of participants
N/A N=291 Randomized Trial Of Achieving Healthy Lifestyles In Psych Rehabilitation
Overweight and Obesity
Primary: Change in Weight Loss in Kilograms (kg) — -1.8; -0.3; -3.4; -0.2 kg
N/A N=257 Randomized Control Trial on Trauma Focused CBT in Zambia
Post Traumatic Stress Disorder · Depression · Risk Behaviors
Primary: Post Traumatic Stress Disorder- Reaction Index (RI) — 1.75; 1.88; 1.38; 0.34 trauma score
N/A N=172 Systematic Multi-domain Alzheimer's Risk Reduction Trial
Dementia · Alzheimer Disease
Primary: Cognitive Change — 0.34; 0.19 z-score — p=0.008
N/A N=276 Randomized Controlled Trial of Prenatal Coparenting Intervention (CoparentRCT)
Parenting
Primary: System for Coding Interactions in Dyads (SCID) Positive Communication Patterns — 2.46; 2.53; 2.25; 2.15 score on a scale — p=.32
N/A N=37 EHR Embedded Comparative Effectiveness Studies--CPS
Disk Herniated Lumbar
Primary: Compliance Rate With Assigned Treatment — 89; 50 percentage of eligible patients
N/A N=2,484 Randomized Controlled Trial to Address Unintended Pregnancy Rates in Low Resource Settings
Contraceptive Usage · Unintended Pregnancy
Primary: Percentage Change in Current Modern Contraceptive Use — -1.1; 1.4; 1.5 percentage of participants
N/A N=415 Pilot Randomized Controlled Trial (RCT): Remote SBIRT Vs. In-Person SBIRT
Pregnancy · Substance Use · Depression
Primary: Completion of SBIRT (Specific Aim 1) — 221; 63 Participants
N/A N=400 Effectiveness of an Evidence-based Stepped Care System for Alcohol and Other Drug Use Problems Among Congolese Refugees in Zambia
Alcohol and Substance-Related Mental Disorders
Primary: Change in Alcohol Use Disorders Identification Test (AUDIT) Score — -12.6; -8.1; -13.8; -10.3 score on a scale
Phase 2 N=15 A Randomized Trial of CT Fluoroscopy-guided Targeted Autologous Blood and Fibrin Glue Patching for Treatment
Cerebrospinal Fluid Leaks
Primary: Change in Median (Headache Impact Test-6) HIT-6 Score From Baseline — -12; -7 score on a scale
N/A N=299 Implementing mHealth for Schizophrenia in Community Mental Health Settings
Schizophrenia
Primary: Patient Health Questionnaire (PHQ)-9 — 11.6; 10.7; 9.6; 10.2 Scores on scale — p=.06
N/A N=555 Randomized Controlled Trial of Wellness Recovery Action Planning
Mental Disorders
Primary: Psychiatric Symptoms Recovery Using the Brief Symptoms Inventory (BSI) — 20.6; 19.29; 19.52; 21.38 symptom severity score — p=0.027
N/A N=85 New Technologies to Help Manage ADHD
Attention Deficit Hyperactivity Disorder
Primary: Medication Continuity: The Number of Days Covered With Medicine — 108.8; 133.3 Days — p=0.04
N/A N=4,774 Pragmatic, Randomized Evaluation of Statin Active Choice to Reach Improved Outcomes Based on Evidence
Cardiovascular Diseases
Primary: Statin Prescribing Rate — 40; 116; 117 Participants
Phase 3 N=451 Randomized Study of Real-Time Continuous Glucose Monitors (RT-CGM) in the Management of Type 1 Diabetes
Type 1 Diabetes
Primary: Change in Glycated Hemoglobin (HbA1c) From Baseline to 26 Weeks in the Continuous Glucose Monitoring (CGM) and Control Groups (for the Cohort With Baseline HbA1c >=7.0%…
N/A N=126 A New Paradigm for Illness Monitoring and Relapse Prevention in Schizophrenia
Schizophrenia · Schizoaffective Disorder
Primary: Relapses in Participants — 20; 22 Participants — p=0.80
N/A N=194 Randomized Controlled Clinical Trial of Weight Loss Programs in Obese Persons
Obesity
Primary: Change in Weight From Baseline to 18 Months — -5.0; -3.2 kg
N/A N=697 A Randomized Controlled Trial of HIV Testing and Linkage to Care at Community Corrections
HIV
Primary: Number of Participants Willing to Undergo Rapid HIV Testing — 318; 60 Participants
N/A N=1,112 Hybrid Collaborative Care Randomized Program Evaluation
Mental Health Disorders
Primary: Veterans RAND-12 Mental Component Score (VR-12 MCS) — 36.82; 36.24; 37.25 score on a scale — p=<0.01
N/A N=249 iSIPsmarter: An RCT Evaluating the Efficacy of a Technology-Based Intervention to Reduce Sugary Drinks in Rural Appalachia
Diet Habit · Sugar-Sweetened Beverages
Primary: Change From Baseline Sugar-sweetened Beverage Fluid Milliters/Day at 9-weeks — -897.0; -291.0 fluid milliters/day
N/A N=1,280 Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
Childhood Traumatic Grief · Post Traumatic Stress · Post Traumatic Stress Disorder
Primary: Posttraumatic Stress Syndrome (PTSS) — 23.41; 21.23; 25.66; 23.40 score on a scale