N/A N=12 Proof of Concept: "Bottom's Up" Seat to Treat Constipation
Constipation Aggravated · Pelvic Floor; Incompetency
Primary: Adverse Events — 0 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=272 Smartmesh Technology in Pelvic Floor Repair Procedures
Pelvic Organ Prolapse
Primary: Number of Patients With a Composite Outcome : Bladder Wound, Rectum Wound, Abnormal Bleeding — 6 Participants
N/A N=30 Restorelle Direct Fix Anterior and Posterior (A&P) for Female Pelvic Organ Prolapse: A Prospective Post Market Study
Pelvic Organ Prolapse (POP)
Primary: Palpability of the Restorelle Direct Fix Anterior and Posterior (A&P) — 30; 0; 0; 0 participants
N/A N=99 Anterior Colporrhaphy Versus Cystocele Repair Using Polypropylene Mesh or Porcine Dermis
Anterior Vaginal Wall Prolapse · Cystocele · Pelvic Organ Prolapse
Primary: Prospective Randomized Trial of Anterior Colporrhaphy Vs. Cystocele Repair Using Polypropylene Mesh or Porcine Dermis — 5; 14; 12 Participants
N/A N=52 Stapled TransAnal Rectal Resection (STARR) With Contour® TranstarTM
Obstructed Defecation Syndrome · Rectocele · Intussusception
Primary: Quality of Life — 3.2; 3.7; 2.8; 3.3 units on a scale — p=0.1340
Phase 4 N=76 Outcomes of Anterior Colporrhaphy Versus Graft Reinforced Anterior Prolapse Repair
Cystocele · Uterine Prolapse · Urinary Incontinence
Primary: Recurrent Stage II or Greater Anterior Vaginal Prolapse — 24; 11 participants — p=0.005
N/A N=121 The Role of Biofeedback in Improving Continence After Anterior Resection
Rectal Neoplasms · Fecal Incontinence · Aged
Primary: Cleveland Clinic Incontinence (CCI) Score — 4.2; 3.7; 1.2; -0.7 score on a scale — p=0.54
N/A N=106 Restorelle® Y Mesh vs. Vertessa® Lite Y Mesh for Laparoscopic and Robotic-assisted Laparoscopic Sacrocolpopexy
Vaginal Vault Prolapse
Primary: Number of Participants With Pelvic Organ Prolapse Recurrence — 2; 1 participants
Phase 3 N=116 Platelet Rich Plasma in Levator Ani Muscle Trauma
Pelvic Floor Disorders
Primary: Changes of Levator Hiatal Area During Valsava — 20.64; 20.35; 22.35; 21.41 Cm2 — p=0.086
N/A N=31 Correlation of Anal Acoustic Reflectometry Parameters With Degree of Rectal Intussusception and Prolapse
Pelvic Floor Disorders
Primary: Opening Pressure — 56.35; 39.01; 23.42 cmH20
Phase 2 N=29 Evaluation of Outcomes of Restoring Pelvic Floor Support With TOPAS in Women With Moderate Fecal Incontinence Symptoms
Fecal Incontinence
Primary: Fecal Incontinence Incidence From Baseline (Pre-treatment) Through 24 Months Post-treatment — 6.9; 3.0; 3.7; 3.7 Number of FI episodes/14 day period
N/A N=173 Comparing Force of Stream to Retrograde Fill Voiding Trial After Vaginal Apex Suspension
Vaginal Apical Prolapse
Primary: Number of Subjects Catheterized Within the Six-week Post-operative Period Following Surgical Repair of Prolapse, Among Those Discharged Without a Urinary Catheter. — 2…
N/A N=190 Performance of Tension Free Vaginal Mesh (Prolift) Versus Conventional Vaginal Prolapse Surgery in Recurrent Prolapse.
Pelvic Organ Prolapse
Primary: Prolapse by "Pelvic Organ Prolapse Quantification System" (POP-Q), at 12 Months — 8; 38; 75; 46 participants — p=<0.05
N/A N=15 Early Feasibility Study of the Reia Vaginal Pessary
Pelvic Organ Prolapse · Prolapse
Primary: The Ability of the Study Device to be Retained During Valsalva Compared to the Ability of the Subject's Current Pessary to be Retained During Valsalva (Change in…
Phase 3 N=104 Biological Mesh Closure of the Pelvic Floor After Extralevator Abdomino Perineal Resection for Rectal Cancer
Rectal Cancer
Primary: 30-day Uncomplicated Perineal Wound Healing — 30; 33 Participants
N/A N=48 A Long Term Follow up of Anterior Meshes for Recurrent Prolapse
Genital Diseases, Female · Pelvic Organ Prolapse
Primary: The Number of Participants With a Current Mesh Erosion or Treated for a Mesh Erosion Since Inserted — 5 Participants
N/A N=12 Studies in Patients With Low Anterior Resection Syndrome (LARS)
Anterior Resection Syndrome · Bowel Dysfunction
Primary: Change of Anorectal Pressure Assessed With the Fecobionics Device — 9.8 cmH2O
Phase 4 N=70 Improvement of Pain Following Robotic Sacrocolpopexy and Rectocele Repair for Pelvic Organ Prolapse
Pelvic Organ Prolapse
Primary: Visual Analog Scales (VAS) for Pain at 18 Hours Postoperatively — 15.0; 20.5 mm — p=0.52
Phase 4 N=199 Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen
Pelvic Organ Prolapse · Urogenital Prolapse · Vaginal Vault Prolapse
Primary: Surgical "Failure" Defined by (i) Anatomic Assessment of Prolapse, (ii) Presence of Bulge Symptoms, and/or (Iii) Retreatment of Prolapse — 18; 8 Participants
N/A N=49 Vaginally Assisted Laparoscopic Hysteropexy Versus Vaginal Hysterectomy
Pelvic Organ Prolapse
Primary: Number of Participants With Recurrence of Pelvic Organ Prolapse — 0; 0 Participants
N/A N=18 Developing Rectal USPE Measures
Microbicide Delivery System Perceptibility and Acceptability
Primary: User Sensory Perception & Experience (USPE; Perceptibility) Scale Item Means — 3.67; 3.29; 3.86; 3.42 units on a scale
N/A N=40 Evaluation of the Rectal Reflex Using Anal Acoustic Reflectometry
Pelvic Floor Dysfunction
Primary: Opening Pressure — 34.44; 15.41 cmH2O
N/A N=78 Feasibility Study of the Reia Vaginal Pessary
Pelvic Organ Prolapse
Primary: Pelvic Floor Distress Inventory-20 (PFDI-20) — 49.46; 62.75 score on a scale — p=.0021
N/A N=698 Pelvic Floor Repair Systems for Prolapse Repair
Pelvic Organ Prolapse
Primary: Percent of Subjects With an ICS (International Incontinence Society) POP-Q (Pelvic Organ Prolapse Quantification System) Stage of </= Stage I in the Posterior…
N/A N=44 Sacro-Spinous Ligaments Anterior Apical Anchoring
Pelvic Organ Prolapse
Primary: The Change With Distance Between the Vaginal Apex and the Introitus — -4.4 centimeters
Phase 4 N=30 Effect of Preoperative Estrogen Treatment on Connective Tissues of the Pelvic Floor
Pelvic Organ Prolapse · Menopause
Primary: Vaginal Wall Composition: Epithelium (Intention to Treat) — 413.9; 314.1 microns — p=0.21
N/A N=124 Effects of an Anal Insert Device in Fecal Incontinence
Fecal Incontinence
Primary: Primary Effectiveness Endpoint — 75.9 percentage of treatment responders
N/A N=58 Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use
Vaginal Vault Prolapse · Pelvic Organ Prolapse · Uterine Prolapse
Primary: Patient Global Impression of Improvement (PGI-I) Score — 39 Participants
N/A N=20 RF Rejuvenation for Pelvic Floor and Vagina
Symptoms Associated With Pelvic Floor Weakness
Primary: Effect of RF on Pelvic Floor Measured by Intentional Muscle Contraction Using Biofeedback EMS — 13.13 mV
Phase 4 N=75 Study of Stapled Transanal Rectal Resection (STARR) Surgery in Refractory Constipation Associated With Obstructive Defecation Syndrome (ODS)
Obstructive Defecation Syndrome · Chronic Constipation · Rectocele
Primary: Percentage of Change (Reduction) in Total ODS Symptom Composite Score From Baseline to One Year Post Procedure — 60.8 percentage of change