N/A N=248 Aspiration in Acute Respiratory Failure Survivors
Dysphagia
Primary: Percentage of Participants Experiencing Aspiration — 70; 52 percentage of participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=25 AspiRATE: Novel Intervention to Acoustically Detect Silent Aspiration in Acquired Dysphagia.
Dysphagia, Oropharyngeal
Primary: Presence or Absence of Aspiration — 42 swallowing events with aspiration
N/A N=50 The Aspirometer: A Noninvasive Tool for Detecting Aspiration Aim 3
Deglutition Disorders
Primary: Numbers of Participants for Which the Aspirometer/HRCA Predicted the Passed Versus Failed Swallow Test Result — 4; 12 Participants
N/A N=513 Oral Suction Intervention to Reduce Aspiration and Ventilator Events: NO-ASPIRATE
Respiratory Failure
Primary: Microaspiration as Measured by Tracheal Amylase — 13,086; 15,298 U/L — p=0.432
N/A N=146 Aspiration of Residual Gastric Contents
Infant, Premature · Nutrition, Enteral
Primary: Enteral Intake on Day of Life 7 — 27.5; 22.6 mL/kg per day — p=0.27
Phase 2 N=14 Cough and Swallow Rehab Following Stroke
Ischemic Stroke
Primary: Maximum Expiratory Pressure — 104.31 cm H2O (pressure measurement) — p=.001
N/A N=25 Respiratory Strength Training in Cardiac Surgical Patients
Cardiovascular Diseases · Thoracic Diseases · Surgery
Primary: Adherence to Respiratory Strength Training — 35750 Repetitions
Phase 2 N=65 Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial
Parkinson's Disease · Dysphagia · Dystussia
Primary: Change in Voluntary Cough Peak Flow — 0.17; 0.51 l/s
N/A N=30 Predictors of the Ability to Protect the Airway in Long-term Ventilated Patients
Swallowing Disorder · Aspiration · Long Term Ventilation
Primary: Muscle Strength — 20; 10 participants
Phase 2 N=30 Respiratory-Swallow Training in Veterans With Oropharyngeal Cancer
Oropharyngeal Dysphagia · Oropharyngeal Cancer
Primary: Optimal Respiratory - Swallow Phase — 43; 86; 88.1 percentage of swallows
N/A N=10 Respiratory Capacity and Swallowing Function in Spinal Disorders: A Pilot Study
Spinal Cord Injuries · Deglutition Disorders
Primary: Number of Participants Displaying Unsafe Swallowing — 0; 0; 0; 0 Participants
N/A N=7 Effect of Nasal Continuous Positive Airway Pressure on The Pharyngeal Swallow in Neonates
Deglutition Disorders · Respiratory Distress Syndrome In Premature Infants · Respiratory Aspiration
Primary: Pharyngeal Phase Dysphagia — 7; 7 Participants
N/A N=154 Oropharyngeal Dysphagia in Patients With Community Acquired Pneumonia
Dysphagia · Pneumonia
Primary: Intra Hospital Mortality — 7; 0 Participants
N/A N=49 Clinical Impact of Respiratory-Swallow Training on Refractory Dysphagia in Oropharyngeal Head and Neck Cancer
Head and Neck Cancer · Dysphagia
Primary: Modified Barium Swallow Impairment Profile (MBSImP) Pharyngeal Total (PT) Score — 11.00; 12.33; 9.84; 10.73 score on a scale
N/A N=452 Study of Impact of Not Measuring Residual Gastric Volume on Nosocomial Pneumonia Rates
Ventilation-Associated Pneumonia
Primary: Compare Ventilator Associated Pneumonia Rates in Patients Receiving Early Enteral Feeding Without Residual Gastric Volume (RGV) Monitoring and in Patients With RGV…
N/A N=152 Nasal and Bronchial Absorption Sampling in RSV Bronchiolitis
Bronchiolitis · Bronchiolitis, Viral · RSV Infection
Primary: The Number of Sampling Visits on Which Participants Are Willing to Undergo Nasosorption and/or NPA Sampling — 124; 60; 0; 0 Sampling visits
N/A N=28 Prophylactic Bronchoscopy After Inhalation Injury in Burn Patients
Inhalation Injury · Pneumonitis · Pneumonia
Primary: All Cause Mortality — 0; 1 participants
Phase 2 N=400 LIPS-A: Lung Injury Prevention Study With Aspirin
Acute Respiratory Distress Syndrome
Primary: Number of Participants Who Developed Acute Respiratory Distress Syndrome (ARDS) Within 7 Days — 20; 17 participants — p=0.53
N/A N=16 Assessing Ventilator Safety in Patients on Pressure-Support Ventilation
Acute Respiratory Failure · Mechanical Ventilation Complication · Ventilator-Induced Lung Injury
Primary: Respiratory System Driving Pressure Measure by Servo Ventilator (DPrs-servo) — 12.3 centimeters of water
N/A N=171 Pivotal Aspiration Therapy With Adjusted Lifestyle Therapy Study
Obesity
Primary: Mean Percent Excess Weight Loss (%EWL) — 31.5; 9.8 Percent Excess Weight Loss
N/A N=12 Aerosol Particle Concentrations Among Different Oxygen Devices for Spontaneous Breathing Patients With Tracheostomy
Transmission, Patient-Professional
Primary: Aerosol Particle Concentrations With Size of 1-3 Micrometer at 1 Foot Away From the Patient — 13000; 11000; 10000; 12000 particles/m3
Phase 2 N=149 Aerosolized Surfactant in Neonatal RDS
Respiratory Distress Syndrome, Newborn
Primary: Number of Participants With Adverse Events as a Measure of Safety and Feasibility — 3; 8; 4; 12 Participants
Phase 4 N=6,824 Applying Best Clinical Practices to Patients at High Risk of Respiratory Complications
Respiratory Complication · Obstructive Sleep Apnea
Primary: Time to "Fitness for Discharge" From the Recovery Room — 165.64; 154.60 Minutes
Phase 2 N=49 Normal Breathing and Swallowing in Healthy Volunteers
Healthy
Primary: Reflexive Cough Testing (With Urge-to-Cough) — 3; 5 units on a scale
Phase 2 N=1,068 Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia
Ventilator-acquired Pneumonia
Primary: Quality of Life - 36-item Short-Form General Health Survey — 40.5; 40.0; 48.9; 45.9 score on a scale — p=0.78
N/A N=117 Endotracheal Tubes for Prevention of Ventilator-associated Pneumonia
Ventilator-acquired Pneumonia
Primary: Percentage of Patients With Tracheal Bacterial Colonization — 8; 7; 9 percentage of tracheal colonization
N/A N=164 Soiled Airway Tracheal Intubation and the Effectiveness of Decontamination by Paramedics
Airway Management · Intubation, Intratracheal · Laryngoscopy
Primary: Difference in First-pass Intubation Success Rates Before and After SALAD Training — 44; 74 Participants
N/A N=59 Assessment of Airway Obstruction in Infants With Lower Respiratory Infections
Bronchiolitis · Respiratory Syncytial Virus Infections
Primary: Lung Function — 0.071; -3.179; 0.186; -3.345 Z score — p=0.0020
Phase 2 N=54 Effectiveness of Continuous Negative External Pressure in Preventing Upper Airway Impairment During Routine Colonoscopy
Airway Obstruction · Apnea · Hypopnea
Primary: RI Events in the cNEP Group Compared to the no cNEP Group, Where RI is Defined as Either: i Oxygen Saturation < 90% or ii. Apneas/Hypopneas of > 15 Sec Duration i…
N/A N=20 Respiratory Muscle Strength Training in Presbyphonia
Presbylarynx
Primary: Post-Treatment Mean in Voice Handicap Index Score — 15.00; 15.75; 18.50 score on a scale — p=0.041