N/A N=16 Comparison of a Septal Stapler to Suture Closure in Nasal Septoplasty
Nasal Obstruction
Primary: Operative Time — 35; 423 seconds
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=42 The Effectiveness of Nasal Corticosteroids Versus Placebo in Nasal Obstruction in Patients With Nasal Septal Deviation
Nasal Obstruction
Primary: Nasal Obstruction as Measured by Nasal Obstruction Symptom Evaluation (NOSE) Scores Following Therapy With Treatment (Triamcinolone Acetonide) and Placebo (Ayr Saline…
N/A N=25 Study of the ENTact Septal Staple System for Tissue Approximation During Septoplasty
Nasal Septum
Primary: Coaptation (Tissue Approximation) — 23 participants
N/A N=40 Safety and Performance of ENTACT Septal Staple System for Septoplasty
Septoplasty
Primary: Percentage of Participants With Clinical Success of the ENTACT Septal Staple System by Examining the Participant's Nasal Cavity at the 21 Day Follow-up Visit — 94.7…
N/A N=47 Nasal Septal Flap for Donor Site Reconstruction
Nasal Septum Perforation
Primary: Mean Change in Post-operative Remucosalization at the Donor Site — 47.8; 37.8; 49.7; 43.5 percentage of remucosalization
N/A N=70 The Vivaer Procedure for Treatment of the Septal Swell Bodies (SWELL)
Nasal Obstruction
Primary: Nasal Obstruction Symptom Evaluation (NOSE) Scale Mean Change — -45.3 score on a scale
Phase 4 N=50 Septorhinoplasty Post-operative Pain Control With SPG Nerve Block
Deviated Nasal Septum
Primary: Post Operative Pain Scores — 3.9; 3.8; 2.7; 2.9 pain score on a scale of 0-10
N/A N=30 Safety and Efficacy Study of Polydioxanone (PDS) Plates in Rhinoplasty
Rhinoplasty
Primary: Live Assessment of Satisfaction With the Grafts — 2; 4 units on a scale
N/A N=50 A Clinical Evaluation of the Sinexus Intranasal Splint Following Functional Endoscopic Sinus Surgery in Patients With Chronic Rhinosinusitis
Chronic Sinusitis
Primary: Device Success Rate — 14; 76; 10 ethmoid sinuses
N/A N=113 Spirox Latera™ Implant Support of Lateral Nasal Wall Cartilage (LATERAL-OR) Study
Nasal Obstruction
Primary: The Primary Efficacy Endpoint is the Percent of Treatment Responders — 101 Participants
N/A N=32 Comparison of Nasal Steroids After FESS in CRSwNP
Sinusitis · Nasal Polyps
Primary: SNOT-22 Scores — 31.5; 10.29; 15.88 units on a scale
N/A N=20 Treatment Outcome Using Vivaer Stylus to Treat Nasal Airway Obstruction
Nasal Obstruction
Primary: Change in NOSE Score — -44.5 units on a scale
N/A N=215 Septal - Success Rate and Clinical Outcome of Septal Implant of Ventricular Defibrillation Lead
Ventricular Tachycardia · Ventricular Fibrillation
Primary: Implant Success Rate at Septal Site — 97; 99 Participants
Phase 3 N=18 Nasal Packing as a Drug Delivery System Postoperatively in Chronic Sinusitis With Polyposis
Chronic Sinusitis · Polyposis
Primary: Olfaction — 20.2; 19.8 units on a scale
N/A N=166 LATERA-OFFICE Study
Nasal Obstruction
Primary: Efficacy: Percent of Treatment Responders — 136 Participants
Phase 2 N=105 Mepolizumab in Nasal Polyposis
Nasal Polyps
Primary: Number of Participants With a Reduced Need for Surgery at Week 25 — 16; 5; 33; 46 Participants — p=0.003
N/A N=72 Balloon Sinus Dilation In Office or OR
Chronic Sinusitis
Primary: Mean Intra-patient Change in SNOT-20 Score at 24 Weeks Post-procedure Compared to Baseline — -1.25; -1.35 scores on a scale
N/A N=50 Clinical Evaluation of the Steroid-Eluting Sinexus Intranasal Splint When Used Following Functional Endoscopic Sinus Surgery (FESS) in Patients With Chronic Sinusitis
Chronic Sinusitis
Primary: Safety as Determined by the Frequency of Serious Adverse Local Tissue Response (SALT) — 6 Number of Sinuses
Phase 3 N=408 Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis
Chronic Rhinosinusitis With Nasal Polyps
Primary: Change From Baseline in Total Nasal Polyp Score at Week 52 — -2.458; -0.380 Score — p=<.0001
N/A N=50 Treatment of Nasal Airway Obstruction Using the Aerin Medical Device
Nasal Obstruction
Primary: Improvement in NOSE Score — 54.8 units on a scale — p=<0.0001
N/A N=100 In-office Placement of the Propel Mini Sinus Implant in the Frontal Sinus Ostia
Chronic Sinusitis
Primary: Patency Rate — 38; 33 sinus sides — p=0.0391
N/A N=39 Quality of Life Impact of Nasal Airway Treatment With Aerin Medical Device
Nasal Obstruction
Primary: Change From Baseline NOSE Score — 53.3; 48.1; 53.5 units on a scale — p=<0.0001
Phase 2 N=10 A Study Evaluating the Efficacy and Safety of ARTISS Human Fibrin Sealant as Used in External Rhinoplasty
Subjects Requesting and Requiring an Open Rhinoplasty
Primary: Edema Severity — 1.25; 1.5; 1.25; 1 units on a scale
N/A N=119 Vivaer® Procedure for Treatment of Nasal Airway Obstruction Study
Nasal Airway Obstruction
Primary: Nasal Obstruction Symptom Evaluation (NOSE) Scale - 3 Month Responder Rate — 88.3; 42.5 percentage of participants
N/A N=151 Randomized Evaluation of Maxillary Antrostomy Versus Ostial Dilation Efficacy Through Long-Term Follow-Up
Chronic Sinusitis
Primary: Sinus Symptom Improvement — -1.59; -1.60; 0.88; 0.88 units on a scale — p=<0.001
Phase 4 N=65 Postoperative Pain Control in Septum and Sinus Surgery
Post-operative Pain · Sinus Surgery
Primary: Number of Doses of Opiate (Narcotic) Pain Medication — 1.0; 1.5 number of doses
Phase 2 N=24 Benralizumab Effect on Severe Chronic Rhinosinusitis With Eosinophilic Polyposis
Chronic Rhinosinusitis (Diagnosis) · Nasal Polyps · Eosinophilia
Primary: Change in Nasal Polyp Score — .9; .3 score on a scale
N/A N=75 A Clinical Evaluation of the Intersect ENT Sinus Device (ASCEND)
Chronic Rhinosinusitis (Diagnosis)
Primary: Randomized Cohort: Difference in Patency Grade of FSO — 1.6; 1.5 score on a scale
N/A N=26 Management of Persistent Epistaxis Using Floseal Hemostatic Matrix
Epistaxis
Primary: Number of Participants With Initial Hemostasis — 10; 11 Participants — p=1.000
N/A N=203 Optimization and Refinement of Technique in In-Office Sinus Dilation 2
Sinusitis
Primary: Mean Intra-patient Change in SNOT-20 Score — -1.16 Scores on a scale