N/A N=465 Improving Transitional Care Experiences in Mental Health
Standard Treatment Versus Engagement Focused Treatment
Primary: Subjective Quality of Life — 3.9; 3.8; 4.3; 4.0 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=331 PACT for Individuals With Serious Mental Illness
Schizophrenia Spectrum & Other Psychotic Disorders
Primary: Provision of Appropriate Preventive and Medical Treatments — 144; 117; 146; 131 Participants
N/A N=134 PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness)
Post Traumatic Stress Disorder · Schizophrenia · Schizoaffective Disorder
Primary: Posttraumatic Stress Disorder (PTSD) Checklist (PCL) — 66.94; 66.33; 51.20; 60.60 score on a scale
N/A N=100 Mental Health Services for Prisoners With SMI
Mental Disorder
Primary: Change in Levels of Aggression Score From Baseline to Month 3 — -4.81; -2.68 score on a scale
N/A N=68 Augmenting Hospitalization for Serious Mental Illness: Cognitive Bias Modification
Depression · Bipolar Disorder · Anxiety Disorders
Primary: Clinical Global Improvement Scale (CGIS) — 14; 20 Participants
N/A N=200 Improving Outcomes for Individuals With Serious Mental Illness and Diabetes
Diabetes Mellitus · Bipolar Disorder · Depression
Primary: Brief Psychiatric Rating Scale (BPRS) at 60 Weeks — 32.04; 35.89 scores on a scale — p=.785
N/A N=287 Life Goals Collaborative Care to Improve Health Outcomes in Mental Disorders
Bipolar Disorder · Schizophrenia · Major Depressive Disorder
Primary: Physical Health-related Quality of Life — 34.00; 33.61 units on a scale
N/A N=22 Skills Training to Enhance Vocational Outcomes in Veterans With Serious Mental Illness
Schizophrenia · Bipolar Disorder · Psychotic Disorders
Primary: Bell-Lysaker Emotion Recognition Task Total Score — 14.8; 16.00 score on a scale — p=.08
N/A N=44 Targeted Self-Management for Epilepsy and Serious Mental Illness (TIME)
Epilepsy · Schizophrenia · Schizoaffective Disorder
Primary: Change in Montgomery Asberg Depression Rating Scale (MADRS) — 16.75; 22.94; 11.21; 21.81 score on a scale — p=0.036
N/A N=87 Mobile Self-Tracking of Mental Health
Schizophrenia · Bipolar Disorder · Schizoaffective Disorder
Primary: Feasibility of Passive Self-tracking of Mental Health — 58 Participants
N/A N=255 Real-Time Mobile Cognitive Behavioral Intervention for Serious Mental Illness
Schizophrenia · Bipolar Disorder
Primary: Score on the Brief Psychiatric Rating Scale (BPRS) — 43.2; 41.6; 42.0; 41.0 units on a scale
N/A N=162 Brief COVID-19 Intervention for People With Serious Mental Illness and Co-Morbid Medical Conditions
Mental Illness · Chronic Disease
Primary: Number of Participants Who Received COVID-19 Vaccine — 56; 50 Participants
N/A N=1,229 Optimizing Behavioral Health Homes for Adults With Serious Mental Illness
Chronic Disease · Mental Health · Behavioral Health
Primary: Change in Patient Activation in Care (PAM, a 13-item Scale) — 56.99; 56.77; 56.84; 58.74 units on a scale — p=<0.0001
N/A N=121 A Transdiagnostic Sleep and Circadian Treatment to Improve Community SMI Outcomes
Mental Disorders
Primary: Impairment (Sheehan Disability Scale) — 14.30; 12.03; 11.76; 6.57 score on a scale — p=0.025
N/A N=151 Project Bridge: Peer Health Navigator Intervention
Schizophrenia · Depression · Medical Disorders
Primary: Changed Score on SF-12 Pain Items From Baseline to 6 Months and 12 Months — -.16; .11; .19; -.18 Changed mean z-score — p=.073
N/A N=392 Individualizing Incentives for Alcohol in the Severely Mentally Ill
Schizophrenia · Bipolar Disorder · Major Depressive Disorder
Primary: Alcohol Use Assessed by Ethyl Glucuronide (EtG) Detection in Urine — 0.66; 0.65; 0.61 proportion uEtG negative
N/A N=10,347 Reducing Cardiovascular Risk in Adults With Serious Mental Illness
Chronic Disease · Mental Disorder · Health Behavior
Primary: Predicted Annual Rate of Change in 10 Year Risk of Fatal or Nonfatal Heart Attack or Stroke — 14.2; 20.8 percentage of annual rate of change
N/A N=242 Wellness Self-Management
Mental Illness · Chronic Medical Illness
Primary: Short Form-12 (SF-12) General Health (Norm Based) — 40.4; 38.9; 42.5; 41.6 units on a scale — p=0.362
N/A N=123 Contingency Management of Alcohol Abuse in the Severely Mentally ILL
Alcohol Abuse · Schizophrenia · Bipolar Disorder
Primary: Alcohol Use as Assessed by Ethyl Glucuronide Detection in Urine — 408.86; 734.79 EtG Value (nanograms per milileter)
Phase 2 N=38 Treating Smokers With Mental Illness
Smoking Cessation · Cigarette Smoking · Schizophrenia
Primary: 7-Day Point Prevalence Abstinence — 5; 3; 4; 5 Participants
N/A N=118 Illness Management and Recovery for Veterans With Severe Mental Illness
Schizophrenia · Schizo-affective Disorder
Primary: Illness Management Ratings — 3.5; 3.3; 3.5; 3.6 units on a scale — p=.8868
N/A N=1,165 Integrated Smoking Cessation Treatment for Smokers With Serious Mental Illness
Cigarette Smoking · Schizophrenia · Bipolar Disorder
Primary: Number of Participants Who Are Abstinent at the Intervention Year 2 Assessment in Cohort 1 — 13; 32; 19 Participants — p=0.013
N/A N=106 Peer Navigators to Address Obesity-Related Concerns for African Americans With Serious Mental Illness
Obesity · Mental Disorder
Primary: Weight — 226.54; 225.46; 218.19; 225.63 pounds (lbs) — p=.025
N/A N=489 Implementing and Sustaining a Sleep Treatment to Improve Community Mental Part 1: Implementation Health Outcomes
Sleep Disorder · Circadian Dysregulation
Primary: Patient-level Outcome: Patient-Reported Outcomes Measurement Information System - Sleep Disturbance — 63.86; 62.10; 62.81; 62.80 T-score — p=<0.001
N/A N=269 Intervention Trial to Decrease Cardiovascular Risk in Persons With Serious Mental Illness
Cardiovascular Risk Factors · Serious Mental Illness
Primary: Global Framingham Risk Score — 11.5; 12.7; 9.9; 12.3 score on a scale
Phase 2 N=53 A Controlled Trial of Serotonin Reuptake Inhibitors Added to Stimulant Medication in Youth With Severe Mood Dysregulation
Mood Disorder · Mental Disorder Diagnosed in Childhood · Attention Deficit and Disruptive Behavior Disorder
Primary: Percentage of Participants That "Much Improved" (Score of 2) in, or "Completely Recovered" (Score of 1) From Their Irritability Severity, as Measured With the Clinical…
N/A N=9,374 Best Practices to Prevent COVID-19 Illness in Staff and People With Serious Mental Illness and Developmental Disabilities in Congregate Living Settings
Intellectual Disability · Developmental Disability · Axis I Diagnosis
Primary: New COVID-19 Group Home Incidence — 1.61; 1.40; 0.16; 0.09 New COVID-19 cases per 100 person-months — p=0.89
N/A N=22 Restoration of Cognitive Function With TDCS and Training in Serious Mental Illness
Schizophrenia · Bipolar Disorder · Schizo Affective Disorder
Primary: Working Memory Capacity Composite Score — .64; .70; .64; .72 Proportion of correct responses — p== .69
N/A N=14 Acceptance and Commitment Therapy for Tobacco Cessation Among Psychiatric Partial Hospital Patients
Tobacco Smoking · Psychiatric Disorder · Psychiatric Hospitalization
Primary: Feasibility of Recruitment: Proportion of Smokers Seen During the Partial Hospital Visit Who Enroll in the Study — 17 Participants
N/A N=240 A Trial of "Opening Doors to Recovery" for Persons With Serious Mental Illnesses
Mental Disorders, Severe · Schizophrenia and Related Disorders · Bipolar Disorder
Primary: Number of Inpatient Psychiatric Stays for Intervention and Control Participants — 1.9; 2.3 Hospitalizations