N/A N=26 Evaluation of Contact Lenses and Conjunctival Staining in Normal Patients
Conjunctival Staining
Primary: Mean Circumlimbal Conjunctival Staining Score — 6.39; 5.55; 5.68 Units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=15 Non-invasive Tear Film Dynamic Measurements in Normal, MGD and ADDE Subjects After Saline Instillation
Aqueous Deficient Dry Eye · Meibomium Gland Dysfunction
Primary: Visual Quality — 0.3; 0.32; 0.19; 0.3 microns
Phase 4 N=43 Evaluation of Electronic LogMar Visual Acuity and Contrast Sensitivity in a Population of Contact Lens Wearers
Visual Acuity
Primary: Visual Acuity (logMAR) — 0.15; 0.21; 0.02; 0.05 logMAR
N/A N=30 Spectacles for Patients With Down Syndrome
Vision, Low
Primary: Adapted Visual Acuity — 0.256; 0.440; 0.356; 0.284 logMAR — p=0.341
Phase 3 N=861 Safety Study for Bepotastine Besilate Ophthalmic Solution in Normal Volunteers
Allergic Conjunctivitis
Primary: Ocular Comfort — 0.13; 0.07; 0.06; 0.02 Scores on a scale
N/A N=14 Contact Lens Insertion and Removal in a Senior Subject Demographic
Visual Acuity
Primary: Overall Success Rate of Insertion and Removal of a Contact Lens — 85.7 Percentage of eyes
N/A N=24 Open Eye Corneal Swelling With Daily Disposable Contact Lenses and no Lens Wear
Corneal Swelling
Primary: Percentage Change From Baseline of Corneal Swelling 8 Hours Post Fit — 0.07; -0.02; 0.14; -0.06 percentage of change from baseline
N/A N=161 Clinical Evaluation of Spherical Soft Contact Lenses, Toric Soft Contact Lenses and Spectacles in Low Astigmats
Visual Acuity
Primary: High Luminance High Contrast Monocular Visual Acuity (LogMAR) — -0.126; -0.028 logMAR
Phase 2 N=42 Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome
Down Syndrome · Refractive Errors
Primary: Distance Visual Acuity — 0.41; 0.41; 0.40; 0.43 logMAR — p=0.92
N/A N=65 Ocular Characteristics in Contact Lens and Spectacle Wear
Visual Acuity
Primary: Non-Invasive Break Up Time (NIBUT) or Non-Invasive Keratograph Break Up Time (NIKBUT) — 8.28; 11.10 Seconds
N/A N=62 Clinical Evaluation of a Reusable Multifocal Optical Design in a Presbyopic Population
Visual Acuity
Primary: CLUE Vision — 57.1 units on a scale
N/A N=20 Wearable Dark-adaptometer in Normal Adult Healthy Volunteers
Photoreceptor Sensitivity Thresholds
Primary: Time to Rod-cone Break (RCB) — 11.34; 9.98 Minutes
N/A N=25 Objective Vision Evaluation of Two Cosmetic Contact Lenses
Visual Acuity
Primary: Distance Binocular Visual Acuity (logMAR) — -0.15; -0.18; 0.00; -0.04 logMAR
Phase 3 N=310 Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers
Allergic Conjunctivitis
Primary: Lid and Lid Margin Erythema, Change From Baseline — 0; 0 Units on a scale
Phase 4 N=11 Wearing-Off Period of Pharmacological Dilation and Anisocoria
Anisocoria
Primary: Number of Participants With Constricting Response to Pilocarpine 1% in the Pharmacologically Dilated Eye — 3 Participants
N/A N=81 Clinical Characterization of Symptomatic Populations
Ametropia
Primary: Meibomian Gland Imaging — 10; 4; 23; 66 eyes
N/A N=23 Evaluation of Vision Effects of a Cosmetic Tinted Hydrogel Contact Lens
Refractive Error
Primary: The Binocular Functional Visual Performance Under Distance Day Time Conditions (250 cd/m2) for Centrally Presented High Contrasts (HC) Time Controlled Visual Acuity…
N/A N=448 Safety and Suitability of ICL for Correction of Refractive Errors Without the Use of Dispersive OVDs
Refractive Errors · Myopia · Myopic Astigmatism
Primary: Unaided Visual Acuity After the Procedure — 0.264; 0.227 LogMar vision
Phase 1 N=34 Clinical Trial to Evaluate the Safety and Tolerability of Lagricel® Ofteno Multi-dose Ophthalmic Solution
Dry Eye
Primary: Presence of Adverse Events (AEs) — 7; 8 Participants — p=0.409
N/A N=230 Study of a Hand-held Device Plus Mobile App Versus Standard Eye Care Devices in Measuring Refractive Error of the Eye
Refractive Errors · Astigmatism
Primary: BVCA Utilizing Refraction Results From Handheld Device Compared to Manual Refraction Methods for the Age Stratum 45 Through 65 Years — 0.06; 0.02; 0.03 logMAR
Phase 4 N=119 Clinical Investigation of the Vision-R800 Device.
Myopia · Hyperopia · Astigmatism
Primary: Subjective Questionnaire Response — 22; 32; 5; 3 Participants
N/A N=35 Toric Contact Lens Performance Study
Astigmatism
Primary: Near Visual LogMAR Acuity — -0.09; -0.02 LogMAR
Phase 3 N=120 A Study to Evaluate the Efficacy of Investigational OTC Eye Drops
Ophthalmic Solutions
Primary: Clinician Assessment of Change From Baseline in Redness at 60 Seconds After First Product Application — 0.31; 0.27; 0.32 units on a scale — p=0.392
Phase 3 N=250 Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers
Allergic Conjunctivitis
Primary: Lid and Lid Margin Erythema, Change From Baseline — 0; 0 Units on a scale
N/A N=30 Marketed Contact Lens Real World Through Focus Curve
Visual Acuity
Primary: Distance Binocular LogMAR Visual Acuity — -1.072; -0.904; 0.9017; 0.557 -10*LogMAR
N/A N=28 Evaluation of On-eye Optical Performances of the RMY-100 Lens
Visual Acuity
Primary: Distance Spherical Aberration (Z4, 0) — 0.350; 0.364 micron
N/A N=10 Evaluation of Surface Refractive Index Shift of Kalifilcon A Lenses Compared to Dailies Total 1, Precision 1 and Biotrue ONEday Lenses
Habitual Soft Contact Lens Use
Primary: Surface Refractive Index Shifts at 5 Minutes — 1.4102; 1.4251; 1.4188; 1.3788 No units
N/A N=127 Evaluation of Senofilcon A With New UV-blocker on a Neophyte Population
Visual Acuity
Primary: Acceptable Lens Fitting — 0.974 Proportion of subjects
Phase 2 N=31 Side Effects of Atropine (SEA) Study
Myopia
Primary: Diameter of the Pupil Measured With a Neuroptix Pupillometer — 4.9; 5.1; 5.9; 5.9 millimeters — p=0.002
Phase 1 N=29 Phase I Clinical Trial to Evaluate the Safety and Tolerability of Ophtalmic Solution PRO-201
Myopia
Primary: Number of Unexpected Adverse Events — 41 adverse events