Phase 2 N=24 Oxidative Stress and Surgical Recovery
Surgical Recovery · Pain, Postoperative
Primary: Phosphorylation of STAT-3 in MDSC (Myeloid-derived Suppressor Cells) — 2.162; 2.025 STAT3 archsinh ratio — p=0.5490
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Early Phase 1 N=103 Implementation of a Rapid Recovery Program in Gynecologic Oncology Surgery: A Pilot Study
Cervical Cancer · Uterine Endometrial Cancer · Ovarian Cancer
Primary: Hospital Stay — 3.0; 3.0 Days — p=0.36
N/A N=246 Functional Recovery and Caregiver Burden Following Surgery in the Elderly
Activities of Daily Living · Caregivers · Ambulatory Surgical Procedures
Primary: Functional Autonomy Measurement System (SMAF) — 4.0; 2.0; 10.9; NA units on a scale
N/A N=56 Enhanced Recovery After Spine Surgery
Enhanced Recovery After Surgery · Spine Surgery
Primary: Patient Score on QoR40 Inventory. — 179.4; 170.3 scores on a scale
Phase 3 N=3,395 Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data
Perioperative Optimization
Primary: 30 Day Hospital Free Days — 27; 27; 26; 27 Number of hospital free days
N/A N=31 Supportive Programs for Supporting Optimal Recovery in Participants Undergoing Gynecological Surgery
Ovarian Neoplasm · Uterine Neoplasm
Primary: Percentage of Participants Retained in the Study — 78.6; 82.4 percentage of participants retained
N/A N=541 Cesarean Section Via Enhanced Recovery
Cesarean Section
Primary: Opioid Consumption — 60.34; 104.33 oral morphine equivalents (mg) — p=< 0.001
N/A N=2,793 Ambulatory Cancer Care Electronic Symptom Self-Reporting for Surgical Patients
Patient Reported Outcomes
Primary: Rates of UCC Visits and Readmissions Between the Team Monitoring and Enhanced Feedback Cohorts up to 30 Days Post-operatively — 31; 38; 44; 60 Participants
N/A N=299 Evaluation of Spine Surgery Analgesic Pathway
Posterior Spine Surgery
Primary: Quality of Recovery — 109; 109 units on a scale — p=0.92
Phase 3 N=72 Postoperative Consequences of Intraoperative NOL Titration
Anesthesia; Adverse Effect
Primary: Pain Scores at 10-minute Intervals for the Initial Hour of Recovery — 0; 0; 1.0; 5.0 score on a scale — p=0.895
Phase 2 N=241 Psychological Influences on Postoperative Recovery
Care, Postoperative · Pain, Postoperative · Surgical Procedures, Operative
Primary: Modified Yale Preoperative Anxiety Scale — 41.59; 37.44; 46.17; 33.65 Score on mYPAS scale — p=.02
N/A N=77 Accelerated Recovery Pathway for Discharge After Surgery in Patients With Pancreatic Cancer
Pancreatic Carcinoma
Primary: Percentage of Patients Discharged by Post-operative Day 5 — 5; 28 Participants
Phase 4 N=44 Pudendal Enhancement of Enhanced Recovery After Surgery (ERAS) for Reconstructive Surgery (PEERS)
Pain Management
Primary: Narcotic Use — 8; 6.75 MME
Early Phase 1 N=70 Continuous Interscalene Block Results in Superior Recovery Throughout the First Postoperative Week
Postoperative Pain · Adverse Effects
Primary: Patients With Pain: Numerical Rating Scale (NRS-11(0-10): 0:no Pain and 10:Severe/Worst Pain) ≥ 4 — 19; 5; 11 participants
N/A N=55 Post- Surgery Recovery: Nerve Blocks w/ Sedation vs. Nerve Block w/ Either Sedation/Gen. Anesthesia
Nausea · Emesis
Primary: Number of Participants With Nausea 1 Hour After Post-anesthesia Care Unit (PACU) Admission — 1; 0; 1; 14 Participants
N/A N=455 Safety of Total Knee Replacement Surgery Before and After the Implementation of Enhanced Recovery Program
Arthroplasty Complications
Primary: Number of Patients With Early Complication — 9; 16; 4 Participants
Phase 4 N=80 Recovery and Analgesia After Surgery for Gynecological Cancer
Gynecological Cancer
Primary: Length of Stay — 4.3; 3.3 days
Phase 4 N=1,570 The Impact of Perioperative Ketamine Infusion on Surgical Recovery
Opioid Use · Enhanced Recovery After Surgery · Anesthesia
Primary: Length of Stay — 5.0; 5.0 days
N/A N=54 Postoperative Virtual Clinical Encounters
Pelvic Organ Prolapse
Primary: Patient Satisfaction Via the Patient Satisfaction Questionnaire -18 — 80.7; 81.2 score on a scale
N/A N=3,000 REstrictive Versus LIbEral Fluid Therapy in Major Abdominal Surgery
Major Abdominal Surgery
Primary: Number of Participants With Disability-free Survival — 1232; 1223 Participants
N/A N=36 Emergence From Anesthesia in Anterior Temporal Lobectomy and Amygdalohippocampectomy Patients
Emergence From Anesthesia
Primary: Volumes of the Hippocampus, Thalamus and Amygdala — 3578; 3903; 3479; 3525 mm3
N/A N=150 Intraoperative Pathway in DIEP Flap Breast Reconstruction
Breast Cancer
Primary: Operative Time — 8.2; 6.9 hours
N/A N=198 Fast-track Rehabilitation After Elective Colorectal and Small Bowel Resection
Colorectal Tumor
Primary: the Length of Hospital Stay — 8; 7 day
N/A N=107 Fast-track Surgery After Gynecological Oncology Surgery
Length of Stay · Postoperative Complications · CRP
Primary: Length of Hospitalization Post-operation — 8.92; 9.67 days — p=0.141
N/A N=30 Tele-Health Electronic Monitoring to Reduce Post Discharge Complications and Surgical Site Infections
Peripheral Vascular Disease
Primary: 30-Day Readmission (Any) — 4; 2 Participants
N/A N=298 Prevena™ Incisional Negative Pressure Wound Therapy in Re-operative Colorectal Surgery
Surgical Site Infection
Primary: Occurrence of Superficial Surgical Site Infection — 11; 21; 107; 128 Participants
N/A N=127 My Surgical Success: A Randomized Controlled Pilot Study of a Pre-surgical Psychological Intervention
Breast Cancer
Primary: Participant Ratings (0-6) for Satisfaction, Usefulness of the Information Presented, Relevance, Ease of Understanding, and Likelihood to Use Skills Learning — 5.9; 5.9…
N/A N=174 Evaluation of the Predictive Nature of the Postoperative CRP on Postoperative Recovery in Patients Undergoing Colorectal Resection (CRP-Track)
Colorectal Postoperative Complication
Primary: C-reactive Protein Rate — 47.9; 81.0; 50.0; 79.5 percentage
Phase 3 N=146 Accelerating Gastrointestinal Recovery
Ovarian Cancer · Fallopian Tube Cancer · Peritoneal Cancer
Primary: Postoperative Length of Hospital Stay — 4.4; 4.3 days — p=0.34
Phase 2 N=118 Enhanced Recovery at Cesarean Birth to Improve Postoperative Outcomes and Reduce Postoperative Length of Stay
Cesarean Section
Primary: Discharge on Postoperative Day #2 — 5; 2 Participants