Phase 2 N=176 Video-assisted Thoracoscopic Surgery - Exparel Study
Pain, Postoperative
Primary: Number of Subjects With Post-operative Opioid Usage — 42; 58 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=216 Comparison of LigaSure to Conventional Electrocoagulation in Video-assisted Thoracoscopic Surgery Lobectomy
Lung Cancer · Complication of Surgical Procedure
Primary: Postoperative Chest Drainage Volume up to Chest Drain Removal, Average 3 Days. — 550; 580 ml
N/A N=36 The Impacts of Pulmonary Rehabilitation Therapy on Patients After Thoracic Surgery
Lung Neoplasms
Primary: Discharge 2weeks Exercise Capacity — 408.61; 311.94 meter(M) — p=<0.05
N/A N=9 Lung Volume Reduction for Severe Emphysema by Stereotactic Ablative Radiation Therapy
Emphysema
Primary: Count of Patients With Grade 3 or Higher Adverse Events. — 3 Participants
N/A N=251 Efficacy of Post-operative Antibiotic Prophylaxis for Thoracic Surgery Requiring Tube Thoracostomy
Antibiotic Prophylaxis
Primary: Number of Participants Who Experienced At Least One Postoperative Infectious Complication — 13; 8 Participants — p=.26
N/A N=201 Powered Vascular Stapler in Video-Assisted Thoracoscopic (VAT) Lobectomies
Non Small Cell Lung Cancer
Primary: Incidence of Intra-Operative Hemostatic Intervention — 0.0533; 0.0833 Proportion transections w/ intervention
Phase 2 N=25 Percutaneous Image Guided Video-Assisted Thoracic Surgery (VATS) Resection of Lung Lesions
Lung Cancer
Primary: Number of Participants With Treatment-related Adverse Events as Assessed by CTCAE v4.0 — 1 Participants
N/A N=71 Powered Echelon Device in VATS Surgery
Non-small Cell Lung Cancer (NSCLC)
Primary: Occurrence of Postoperative Air Leaks — 45.8; 67.9; 88.9 percentage of participants
Phase 4 N=121 PleuraSeal Post Market Study (Europe)
Lung Disease · Pulmonary Lobectomy
Primary: Percentage of Subjects Remaining Air Leak Free From Time of Skin Closure to Hospital Discharge. — 41.9; 30.5 Percentage of participants — p=0.257
N/A N=10 Feasibility Study for Intrathoracic Nerve Stimulation
Postoperative Pain
Primary: Pain as Measured by the Visual-analog Scale — 1 units on a scale
N/A N=50 A Prospective, Multi-Center Evaluation of a Powered Vascular Stapler in Video-Assisted Thoracoscopic Lobectomies
Non-Small Cell Lung Cancer
Primary: Incidence of Intra-Operative Hemostatic Interventions — 1.8 Percentage of vessel transections
N/A N=105 Evaluation of a Powered Surgical Stapler in Video-Assisted Thoracoscopic Lung Resection Procedures in Korea
Non-small Cell Lung Cancer (NSCLC)
Primary: Occurrence of Prolonged Air Leaks — 0.0; 5.8; 37.5 percentage of participants
N/A N=48 Comparative Study of Nonintubated Uniport Thoracoscopic Surgery Using Thoracic Paravertebral Nerve Block Versus Intercostal Nerve Block for Peripheral Solitary Pulmonary Nodule Patients
Peripheral Solitary Pulmonary Nodule or Tuberculoma
Primary: Comparing the Inflammatory Markers During the Operation After the Intervention of the Each Group — 33; 35; 39; 42 pg/L — p=0.025
Phase 4 N=65 Assessment of Intercostal Block Scheduling in Preventing Acute Surgical and Post-surgical Pain in Thoracoscopic Surgery
Chest Pain · Surgery
Primary: Analgesic Use — 33.35; 35.32 MG
N/A N=164 Disposable Powered Articulating Linear Cutter Stapler in Total-Thoracoscopic Anatomic Lobectomy (Segmentectomy)
Lung Cancer
Primary: Number of Participants With Anastomosis Success — 79; 83 Participants — p=0.9727
N/A N=144 HW006 LATERAL Thoracotomy
Left Sided Heart Failure
Primary: Subject is Alive on Original Device, Transplanted, or Explanted for Recovery at 6 Months — 128 Participants — p=0.0003
N/A N=80 Use of a New Stapling Device in General Thoracic Surgery
Thoracic Cancer
Primary: Number of Participants With Product Malfunction — 0 Participants
N/A N=52 Application of Carbon Dioxide for Identifying the Intersegmental Plane in Thoracoscopic Segmentectomy
Lung Cancer · Pulmonary Nodule, Solitary · Segmentectomy
Primary: The Intersegmental Border Appearance Time During the Surgery. — 748.74; 157.11 seconds
Phase 4 N=60 The Use of Paravertebral Block for Cardiac Surgery
Mitral Valve Insufficiency
Primary: Postoperative Fentanyl — 4.51; 6.14 microgram/kilogram
Phase 3 N=147 Comparison of Three Different Pain Blocks for Subjects Undergoing VATS (Video Assisted Thoracoscopic Surgery) Procedure.
Video Assisted Thoracoscopic Surgery · Pain, Postoperative · Pain, Acute
Primary: The Primary Endpoint of This Study Will be VAS Pain Score at 24 Hours — 4.0; 4.5; 3.0 units on a scale
N/A N=40 Lung Collapse With Bronchial Blocker
Video-assisted Thoracoscopic Surgery · Lung Isolation Device · One-lung Ventilation
Primary: Time to Obtain Complete Lung Collapse — 47.8; 32.5 minutes
Phase 2 N=110 Esophagectomy in Treating Patients With High-Grade Dysplasia of the Esophagus or Stage I, Stage II, or Stage III Esophageal Cancer
Esophageal Cancer
Primary: Peri-operative Mortality at 30 Days — 0.029 proportion of participants
N/A N=100 LSA Reconstruction With Laser Fenestration During the TEVAR
Type B Aortic Dissection
Primary: Freedom From All-cause Reintervention, All-cause Mortality and Major Adverse Events Within 30 Days After Procedure — 84 Participants
N/A N=304 Physician-Sponsored IDE for the Talent Endoluminal Stent Graft System for the Treatment of Thoracic Lesions
Thoracic Aortic Aneurysms · Thoracic Transections · Intramural Hematoma
Primary: Number of Participants With Successful Endoluminal Treatment of Thoracic Lesion — 294 Participants
Phase 4 N=33 Efficacy of Intercostal CryoAnalgesia in Robotic Lung Resection
Pain, Postoperative · Lung Diseases
Primary: Change in Visual Analogue Scale (VAS) Pain Score — 4.94; 7.50; 4.57; 6.25 scores on a scale
Phase 3 N=91 Minimally Invasive Thoracic Surgery Intercostal Nerve Block Trial
Thoracic Diseases · Postoperative Pain · Opioid Use
Primary: Average Daily In-Hospital Use of Opioids — 40; 45 Oral Morphine Equivalent per Day
Phase 3 N=100 To Evaluate the Safety and Efficacy for GORE TAG Thoracic Endoprosthesis in the Treatment of Thoracic Aortic Disease
Aneurysm, Dissecting · Aortic Aneurysm, Thoracic
Primary: Percentage of Participants With Technically Successful Implant — 99.0 percentage of participants
N/A N=10 Treatment of Complicated Parapneumonic Effusion With Fibrinolytic Therapy Versus VATs Decortication
Parapneumonic Effusion · Empyema, Pleural · Coagulopathy
Primary: Hospital Length of Stay — 12.4; 8.4 days
N/A N=258 Navigation Endoscopy to Reach Indeterminate Lung Nodules Versus Trans-Thoracic Needle Aspiration
Lung Nodule
Primary: Diagnostic Accuracy — 94; 81 Participants — p=0.003
N/A N=39 Thoracoscopic Sentinel Lymph Node Biopsy in Patients With Stage I or Stage II Breast Cancer
Breast Cancer
Primary: Success Rate in Removing Sentinel Lymph Nodes by Thoracoscopy — 31 participants