Phase 3 N=120 Pediatric Tonsillectomy Pain Reduction Study
Postoperative Pain
Primary: Total Number of Post-operative Doses of Analgesics. — 12; 12; 14 number of doses
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Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=50 Management of Post-Tonsillectomy Pain in Pediatric Patients
Pain, Postoperative · Tonsillar Hypertrophy · Tonsillitis
Primary: Number of Participants With FLACC Pain Scores ≥7 From POD 1 Through POD 3 — 1; 1 participants
Phase 2 N=172 Celecoxib After Tonsillectomy
Tonsillectomy
Primary: Difference in Number of Days Requiring Rescue Pain Medication — 5.00; 5.75 Days
N/A N=40 Lactobacillus Rhamnosus GG in the Middle Ear and Adenoid Tonsil
Upper Respiratory Infection · Acute Otitis Media
Primary: Lactobacillus Rhamnosus GG in Middle Ear Effusion and Adenoid Tonsil — 4; 1 Samples — p=0.05
Phase 2 N=116 Effect of Steroids on Post-tonsillectomy Morbidities
Postoperative Pain · Postoperative Nausea and Vomiting
Primary: Maximum Severity of Post-operative Pain — 37; 26; 13; 21 participants — p=0.033
N/A N=30 Comparison of Sleep Study Results After Partial Intracapsular Tonsillectomy Versus Total Tonsillectomy
Sleep-disordered Breathing · Obstructive Sleep Apnea
Primary: Median Change in Apnea-hypopnea Index (AHI) — 3.8; 8.0 events per hour of sleep — p=.590
N/A N=200 Penicillin and Metronidazole in Treatment of Peritonsillar Abscess
Peritonsillar Abscess
Primary: Number of Participants With Recurrence of Peritonsillar Abscess — 10; 10 Participants — p=0.05
N/A N=24 Efficacy and Safety of Irreversible Electroporation for Chronic Symptomatic Tonsillar Hypertrophy Treatment
Tonsillar Hypertrophy
Primary: Change of Tonsil(s) Size at 3 Months Compared to the Baseline. — -1.13; -1.26 Scores on a scale
Phase 2 N=688 Postoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy
Tonsillectomy · Adenoidectomy
Primary: Number of Participants With Level 3 Postoperative Hemorrhage — 10; 4 Participants
N/A N=58 Comparing Healthcare Utilization Between Adenotonsillectomy Patients With and Without Postoperative Antibiotic Use
Snoring · Strep Throat
Primary: Healthcare Utilization — 5; 16; 5; 8 participants
N/A N=60 A Study of BiZact™ on Children and Adolescents Undergoing Tonsillectomy
Tonsillectomy
Primary: Intra-operative Blood Loss — 1.7 mL
Phase 2 N=66 Pediatric Pain Optimization After Tonsillectomy
Obstructive Sleep Apnea · Tonsillitis · Pain, Procedural
Primary: Total Amount of Opioid Medications Administered — 1.5; 0.9; 0.5 morphine mg equivalents/kg — p=0.045
N/A N=36 Preoperative Gabapentin for Post-tonsillectomy Pain in Children
Post Operative Pain Management in Children With Tonsillectomy/Adenoidectomy
Primary: Total Oral Analgesia Consumption — 0.228; 0.224; 0.200; 0.193 cumulative hydrocodone (mg/kg)
N/A N=186 Adenotonsillectomy for Obstructive Sleep-Disordered Breathing in Childhood:The Chania Community Oximetry-Based Study
Sleep Disordered Breathing · Obstructive Sleep Apnea · Snoring
Primary: Change in Number of Subjects Without Oxygenation Abnormalities — 12; 10 Participants — p=0.54
N/A N=48 A Study of BiZact™ on Adults Undergoing Tonsillectomy
Tonsillectomy
Primary: Pain Assessment Using a Visual Analog Scale (VAS) — 5.4 units on a scale
Phase 3 N=229 Clinical Study for Comparative Assessment of Efficacy and Safety of Angal S, Topical Spray and ANTI-ANGIN® FORMULA, Topical Metered Spray in Treatment of Patients With Uncomplicated Acute Infectious and Inflammatory Diseases of the Pharynx, Accompanied by a Sore Throat
Sore Throat
Primary: Percentage of Patients Without Sore Throat According to the Tonsillopharyngitis Severity Score (TSS) — 89.47; 75.65; 7.02; 19.13 Percentage of Participants — p=0.00001
N/A N=453 Childhood Adenotonsillectomy Study for Children With OSAS
Obstructive Sleep Apnea · Snoring
Primary: Improvements in Attention/Executive Domain Index of the Developmental Neuropsychological Assessment (NEPSY) From Baseline to 7 Months. — 7.1; 5.1 units on a scale — p=0.16
Phase 3 N=60 Magnesium vs Placebo for Tonsillectomy
Pain
Primary: Postoperative Pain — 30; 45 scores on a scale*minutes